Results 141 to 150 of about 115,678 (349)
Aging Cell, EarlyView.Strenuous exercise affects biological aging in professional soccer players. DNA methylation markers analyzed from saliva samples showed epigenetic rejuvenation of the players after soccer games. Furthermore, analyses within the early recovery phase of athletes suggest a potential link between epigenetic markers and injury risk. Our study highlights the
Robert T. Brooke +12 more
wiley +1 more source
Kidney replacement and conservative therapies in rhabdomyolysis: a retrospective analysis
BMC NephrologyBackground Toxic renal effects of myoglobin following rhabdomyolysis can cause acute kidney injury (AKI) with the necessity of kidney replacement therapy (KRT).
Jonathan de Fallois +5 more
doaj +1 more source
The Human Cardiac “Age‐OME”: Age‐Specific Changes in Myocardial Molecular Expression
Aging Cell, EarlyView.A multi‐omics analysis was performed to uncover the molecular landscape of human cardiac ageing. We report several insights for the first time: a decrease in proteins composing the structural machinery of the heart; a likely compensatory increase in energetic flux and redox reductive capacity; and an increase in lysosomal activity.
Cassandra Malecki +20 more
wiley +1 more source
Myoglobin and cytochrome response during repair of iron deficiency in the rat. [PDF]
, 1965 P. R. Dallman, Herbert C. Schwartz
openalex +1 more source
British Journal of Pharmacology, EarlyView.Abstract DNA methylation controls DNA accessibility to transcription factors and other regulatory proteins, thereby affecting gene expression and hence cellular identity and function. As epigenetic modifications control the transcriptome, epigenetic dysfunction is strongly associated with pathological conditions and ageing.
Christopher H. Switzer
wiley +1 more source
Structural interpretation of the amino acid sequence of a second domain from the Artemia covalent polymer globin [PDF]
, 1990 Artemia has a complex extracellular hemoglobin of Mr 260,000 comprising two globin chains (Mr 130,000) each of which is a polymer of eight covalently linked domains of Mr 16,000.
Alard, Philippe +8 more
core +1 more source
The FEBS Journal, EarlyView.l‐serine levels in the human brain are maintained by the phosphorylated pathway, a three‐step process catalyzed by phosphoglycerate dehydrogenase (PHGDH), phosphoserine aminotransferase (PSAT) and phosphoserine phosphatase (PSP). These enzymes assemble in a metabolon called the serinosome. The double R27S/D32G PSP variant was identified in the brain of
Silvia Sacchi +10 more
wiley +1 more source
A note on the effect of post-mortem maturation on colour of bovine Longissimus dorsi muscle [PDF]
, 2010 peer-reviewedFinancial support to P.G. Dunne was provided under the Walsh Fellowship programme of Teagasc.Fifteen heifers were housed and fed a concentrate diet while 54 counterparts grazed at pasture for 90 days at which stage six heifers from each ...
Dunne, Peter G. +2 more
core
THE OPTICAL ROTATORY DISPERSION OF RIGHT-HANDED α-HELICES IN SPERM WHALE MYOGLOBIN [PDF]
, 1961 Peter Urnes, Kazutomo Imahori, Paul Doty
openalex +1 more source
The FEBS Journal, EarlyView.The scaffold protein GKAP and the hub protein LC8 form a well‐defined hexameric complex, with the stoichiometry of 2 GKAP : 2 LC8 dimers. NMR and molecular dynamics calculations confirm that the LC8‐binding segment of GKAP is intrinsically disordered even in the complex form.
Eszter Nagy‐Kanta +10 more
wiley +1 more source