Results 141 to 150 of about 54,674 (269)

Protein engineering studies of myoglobin

open access: yes, 1998
The goals of the work described in this thesis were to gain further insight into structure-function relationships in the oxygen binding protein myoglobin, alter the structure of this protein to enhance a low level latent peroxidase function, and to add
Maurus, Robert
core   +1 more source

Survival of Listeria monocytogenes and Salmonella Typhimurium in Pepperoni With Reduced Salt and Sodium Nitrite Levels, and Sublethal Thermal Treatments

open access: yesJournal of Food Safety, Volume 46, Issue 5, October 2026.
Reduced salt and sodium nitrite pepperoni formulations were challenged with Listeria monocytogenes and Salmonella Typhimurium and subjected to fermentation followed by a postfermentation thermal treatment and drying. Enhanced thermal treatments improved pathogen reductions across formulations, supporting the importance of validated multihurdle ...
Shannon Heapes   +6 more
wiley   +1 more source

Optimized Stacking Ensemble Machine Learning for Nondestructive Toxicological Risk Assessment of Fish Meat Using Hyperspectral Imaging

open access: yesJournal of Food Safety, Volume 46, Issue 5, October 2026.
Hyperspectral imaging and an optimized stacking ensemble learning model are developed for rapid, nondestructive toxicological assessment of fish meat. This framework integrated multiple machine learning classifiers to accurately distinguish toxicologically contaminated fish from fresh samples using both reduced (25‐band) and full (224‐band) spectral ...
Muhammad Aqeel   +5 more
wiley   +1 more source

Leonurine Ameliorates Doxorubicin‐Induced Cardiotoxicity via STING/NF‐κB/NLRP3 Inflammasome Signaling Pathway

open access: yesAdvanced Science, Volume 13, Issue 49, 3 September 2026.
ABSTRACT Doxorubicin‐induced cardiomyopathy (DIC) remains a dose‐limiting clinical challenge. This study reveals that cardiac vascular endothelial cells (CVECs) act as initial sensors of doxorubicin cardiotoxicity: circulating doxorubicin activates the cGAS‑STING pathway in CVECs, triggering NLRP3 inflammasome‑mediated pyroptosis and release of ...
Wang Jun   +10 more
wiley   +1 more source

Adipocyte Myoglobin Is a Determinant of Energy Expenditure and a Potential Target to Limit Obesity

open access: yesAdvanced Science, Volume 13, Issue 51, 14 September 2026.
Myoglobin, known as a muscle oxygen‐carrying protein, is shown to play a key role in fat cells that burn energy. Loss of myoglobin reduces the body's ability to generate heat and increases obesity risk, while restoring it improves metabolism. The study identifies myoglobin as a regulator of fat burning and a potential target to enhance energy ...
Christian Strehlau   +22 more
wiley   +1 more source

Continuous Purification of mRNA Produced by In Vitro Transcription Using High Performance Countercurrent Membrane Purification

open access: yesBiotechnology and Bioengineering, Volume 123, Issue 9, Page 2303-2311, September 2026.
ABSTRACT Messenger ribonucleic acid (mRNA) therapeutics produced by in vitro transcription must be purified to remove residual enzymes and free nucleotides. This study examines the use of high‐performance countercurrent membrane purification (HPCMP) for the purification of mRNA therapeutics based on differences in the rate of diffusion across ...
Ziqiao Wang   +3 more
wiley   +1 more source

The High‐Sensitivity C‐Reactive Protein−Albumin−Lymphocyte Index Is a Prognostic Marker for All‐Cause and Cardiovascular Mortality in Patients With ST‐Elevation Myocardial Infarction

open access: yesCatheterization and Cardiovascular Interventions, Volume 108, Issue 3, Page 1034-1046, September 1, 2026.
ABSTRACT Background Inflammation and immune dysfunction may worsen the prognosis of patients with ST‐segment elevation myocardial infarction (STEMI). Aims This study aimed to assess whether the high‐sensitivity C‐reactive protein–albumin–lymphocyte index (hsCALLYI) could be used to predict the prognosis of STEMI patients who received emergency ...
Xinuo Ma   +8 more
wiley   +1 more source

Rhabdomyolysis Associated With Heated Massage Therapy in a Patient Without Major Trauma: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT A 29‐year‐old professional dancer developed rhabdomyolysis after distal radial fracture fixation complicated by laryngospasm, negative pressure pulmonary oedema, suxamethonium use, and ICU admission. Creatine phosphokinase (CPK) peaked at 36,429 U/L with dark urine and hyperkalaemia.
Ashani Ratnayake   +5 more
wiley   +1 more source

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