Results 171 to 180 of about 54,674 (269)

Oxygenaging: A Physiological Framework for Geroscience

Aging Cell, Volume 25, Issue 9, September 2026.
Mechanisms of aging disrupt oxygen homeostasis through three converging processes: oxygen‐cascade impairment, microvascular dysfunction, and molecular maladaptation. “Oxygenaging” integrates these domains to explain how declining oxygen delivery and utilization drive mitochondrial instability and amplify the effect of the hallmarks of aging.
Stefano Donega, Kenneth W. Fishbein, Paolo Dominelli, Allison B. Herman, Rafael de Cabo, Myriam Gorospe, Luigi Ferrucci   +6 more
wiley   +1 more source

New Water Oxidation Mechanism in Photosystem II Resolves Major Experimental Controversies

Angewandte Chemie, Volume 138, Issue 35, 24 August 2026.
In Photosystem II Oxygen Evolving Complex, we discovered the O3‐O6 peroxide at lower energy. Assignment of the O3 ligated by histidine (His337) as a slow exchanging substrate and its coupling with O6 give the O─O bond formation mechanism most consistent with all currently available experimental data. Proposal shows how protein environment can steer the
Yulia Pushkar
wiley   +2 more sources

Non‐Invasive Assessment of Endothelial Dysfunction and Arterial Stiffness in Fontan Circulation

European Journal of Clinical Investigation, Volume 56, Issue 9, September 2026.
The Fontan procedure is the definitive treatment for complex congenital heart disease, creating a circulation without a subpulmonary ventricle. This altered hemodynamic state negatively affects endothelial function, contributing to progressive organ dysfunction and long‐term morbidity.
Amalia Baroutidou, Eleni Pagkopoulou, Vasileios Kamperidis, Antonios Ziakas, Theodoros Dimitroulas, George Giannakoulas   +5 more
wiley   +1 more source

MYOGLOBIN CONCENTRATION IN FLORIDA MANATEE MUSCLE TISSUE**

For many marine mammals, they must dive to varying depths to obtain the food they need for survival. For these mammals to dive, typically higher levels of myoglobin within skeletal muscle provide needed stored oxygen for ATP production to fuel swim ...
Mitchell, Kiara, Newton, Cori N., Scray, Andru, Hendrix*, Kara   +3 more
core  

Physicochemical Quality and Chemical Safety of Commercial Wet Cat Food: Composition, Oxidation, Biogenic Amines, and Trace Elements

Journal of Animal Physiology and Animal Nutrition, Volume 110, Issue 5, Page 663-673, September 2026.
ABSTRACT This study investigated the physicochemical characteristics and chemical safety of commercial wet cat foods marketed in Brazil. Twenty products labeled as beef, chicken and fish flavors were analyzed for proximate composition, pH, lipid and protein oxidation, biogenic amines, and essential and potentially toxic trace elements.
Marina Teixeira de Vries Mársico, Eliane Teixeira Mársico, Celso Fasura Balthazar, João Paulo de Sá Felizardo, Roberto Meigikos dos Anjos, Erick Almeida Esmerino, Sérgio Borges Mano   +6 more
wiley   +1 more source

Exertional heat stroke-related acute kidney injury: novel animal and cellular models. [PDF]

Ren Fail
Liu J, Hao J, Kang P, Zhang Y, Shen W, Chen P, Chen J, Sun X, Chen X.   +8 more
europepmc   +1 more source

Hypoxia‐inducible factor‐1a (HIF1a) as a context‐dependent integrator of metabolic stress in skeletal muscle

The Journal of Physiology, Volume 604, Issue 18, Page 7539-7558, 15 September 2026.
Abstract figure legend Hypoxia‐inducible factor‐1a (HIF1a) integrates physiological and pathological inputs in skeletal muscle, including exercise, circadian timing, cytotoxins and disease. These inputs alter mitochondrial oxidative function, redox state, reactive oxygen species, and local oxygen availability, leading to intermittent or sustained HIF1a
Nicole Welch, Pugazhendhi Kannan, Seshu Vardhan Pothabathula, Annette Bellar, Abhishek A. Chakraborty, Saurabh Mishra, Srinivasan Dasarathy   +6 more
wiley   +1 more source

Native-Like Protein Structures in Vacuo: Steric Cooperativity as a Kinetic Barrier to Denaturation. [PDF]

JACS Au
Bleiholder C, Pedrete T, Lee J, Liu FC.
europepmc   +1 more source

Interindividual differences in dyspnea during acute hypoxic exercise in healthy adults: A single exposure to simulated altitude at ~9000 ft

Physiological Reports, Volume 14, Issue 17, September 2026.
Abstract The growing accessibility of simulated altitude facilities (~13%–16% fraction of inspired oxygen [FIO2]) has expanded their use to broader recreational populations. Although acute normobaric hypoxia reduces arterial oxygen saturation and increases ventilatory and sympathetic responses, interindividual variability in dyspnea during hypoxic ...
Jacob L. Schwartz, Aisha Khan, Robert F. Bentley   +2 more
wiley   +1 more source

Prostaglandin E-major urinary metabolite as a potential biomarker of muscle inflammation following physical exercise, considering gender differences. [PDF]

Sci Rep
Okayasu I, Huang J, Fujita Z, Cox AJ, Suzuki K.   +4 more
europepmc   +1 more source