Results 41 to 50 of about 4,398 (180)
Clinical Case Reports, Volume 14, Issue 6, June 2026.ABSTRACT We present the case of a 78‐year‐old woman with metabolic syndrome and a history of multiple ischemic strokes who developed progressive symmetrical proximal muscle weakness, predominantly affecting the lower extremities, while on atorvastatin.
Nischal Shrestha +2 more
wiley +1 more source
Journal of Public Health and Primary CareRhabdomyolysis can lead to variable clinical presentation and complications putting life at risk. Patients with preexisting low serum 25(OH) Vitamin D are at high risk of exertional rhabdomyolysis during strenuous activities.
Kanwarpreet Singh Sandhu +1 more
doaj +1 more source
Think muscle; Think rhabdomyolysis
Journal of Acute Disease, 2018 Rhabdomyolysis is the breakdown of striated muscle cells resulting in leakage of cell matter into the extra-cellular space. It can present with myalgia, muscle weakness and swelling. Episodes of passing of dark tea-coloured urine have also been reported.
Fatimah Lateef, Arunima Gupta
doaj +1 more source
The return of metabolism: biochemistry and physiology of glycolysis
Biological Reviews, Volume 101, Issue 2, Page 751-803, April 2026.ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning +19 more
wiley +1 more source
Implementation of Drug‐Induced Rhabdomyolysis and Acute Kidney Injury in Microphysiological System
Advanced Functional Materials, Volume 36, Issue 25, 26 March 2026.A modular Muscle–Kidney proximal tubule‐on‐a‐chip integrates 3D skeletal muscle and renal proximal tubule tissues to model drug‐induced rhabdomyolysis and acute kidney injury. The coculture system enables dynamic tissue interaction, functional contraction monitoring, and quantification of nephrotoxicity, revealing drug side effect‐induced metabolic ...
Jaesang Kim +4 more
wiley +1 more source
Rhabdomyolysis and Cardiomyopathy in a 20-Year-Old Patient with CPT II Deficiency
Case Reports in Genetics, 2014 Aim. To raise the awareness of adult-onset carnitite palmitoyltransferase II deficiency (CPT II) by describing clinical, biochemical, and genetic features of the disease occurring in early adulthood. Method.
M. Vavlukis +6 more
doaj +1 more source
The Journal of Physiology, Volume 604, Issue 5, Page 1840-1871, 1 March 2026.Abstract figure legend We have developed a computational model of energy metabolism in fast‐twitch oxidative glycolytic muscle fibres. The model considers thermodynamically constrained enzyme kinetics derived from in vitro data and was validated against in vivo data from phosphorus magnetic resonance spectroscopy.
Jana Disch +4 more
wiley +1 more source
Pulse Steroid Therapy in a Patient With Refractory Rhabdomyolysis of Unknown Etiology: A Case Report
Clinical Case Reports, Volume 14, Issue 2, February 2026.ABSTRACT Rhabdomyolysis is conventionally treated with aggressive fluid resuscitation and elimination of the inciting factor, whereas corticosteroids are typically limited to cases of immune‐mediated myopathy. We describe an 18‐year‐old female who developed profound bilateral lower‐limb swelling, bullae formation, and motor weakness following a viral ...
Mustafa Majid +10 more
wiley +1 more source
Novel heterozygous mutations in the PGAM2 gene with negative exercise testing
Molecular Genetics and Metabolism Reports, 2018 Pathogenic variants in the PGAM2 gene are associated with glycogen storage disease type X (GSDX) and is characterized by exercise induced muscle cramping, weakness, myoglobinuria, and often tubular aggregates in skeletal muscle.
M. Sidhu +3 more
doaj +1 more source