Results 1 to 10 of about 22,402 (256)
Plasmatology, 2013 Discolored urine is a common reason for office visits to a primary care physician and urology referral. Early differentiation of the type or cause of discolored urine is necessary for accurate diagnosis and prompt management.
Prashant Veerreddy MD, MPH
exaly +3 more sources
Paroxysmal Nocturnal Hemoglobinuria
Journal of Nepal Medical Association, 2005 Paroxysmal nocturnal hemoglobinuria (PNH) is a rare hemolytic disorder of acquired origin and is clinically manifested by chronic hemolysis, thromboses in various sites, and bone marrow failure.
Buddhi P Paudyal +4 more
doaj +7 more sources
Paroxysmal Nocturnal Hemoglobinuria [PDF]
Blood, 2014 AbstractParoxysmal nocturnal hemoglobinuria (PNH) is a rare bone marrow failure disorder that manifests with hemolytic anemia, thrombosis, and peripheral blood cytopenias. The absence of two glycosylphosphatidylinositol (GPI)-anchored proteins, CD55 and CD59, leads to uncontrolled complement activation that accounts for hemolysis and other PNH ...
M. Tublin +5 more
openaire +3 more sources
Paroxysmal Nocturnal Hemoglobinuria: Biology and Treatment
Medicina (Lithuania), 2023 Paroxysmal nocturnal hemoglobinuria (PNH) is a nonmalignant clonal hematopoietic disorder characterized by the lack of glycosylphosphatidylinositol-anchored proteins (GPI-APs) as a consequence of somatic mutations in the phosphatidylinositol glycan ...
Carlos Bravo-Perez +2 more
exaly +2 more sources
Ravulizumab: a novel C5 inhibitor for the treatment of paroxysmal nocturnal hemoglobinuria
Therapeutic Advances in Hematology, 2019 Paroxysmal nocturnal hemoglobinuria (PNH) is a rare stem cell disorder characterized by hemolytic anemia, bone marrow failure, and thrombosis. Until recently, the complement inhibitor, eculizumab, was the only United States Food and Drug Administration ...
Robert Stern, Nathan Connell
exaly +2 more sources
Frontiers in Physiology, 2021 BackgroundThe coronavirus disease-2019 (COVID-19) pandemic impacted healthcare services for kidney disease patients. Lockdown and social distancing were mandated worldwide, resulting in closure of medical services.
Samy Hakroush +3 more
doaj +1 more source
Blackwater Fever Treated with Steroids in Nonimmune Patient, Italy
Emerging Infectious Diseases, 2023 Causes of blackwater fever, a complication of malaria treatment, are not completely clear, and immune mechanisms might be involved. Clinical management is not standardized.
Anna Rita Di Biase +7 more
doaj +1 more source
Porcine Babesiosis Caused by Babesia sp. Suis in a Pot-Bellied Pig in South Africa
Frontiers in Veterinary Science, 2021 Babesiosis is a worldwide, tick-borne disease of economic importance in livestock caused by Babesia spp., which are hemoparasitic piroplasms that target the host erythrocytes.
Alida Avenant +4 more
doaj +1 more source
Pegcetacoplan versus Eculizumab in Paroxysmal Nocturnal Hemoglobinuria.
New England Journal of Medicine, 2021 BACKGROUND Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, acquired disease characterized by chronic complement-mediated hemolysis. C5 inhibition controls intravascular hemolysis in untreated PNH but cannot address extravascular hemolysis ...
P. Hillmen +18 more
semanticscholar +1 more source
Silicone Oil Decreases Biofilm Formation in a Capacitance-Based Automatic Urine Measurement System
Sensors, 2021 Capacitance-based automatic urine measurement is a validated technique already implemented in clinical practice. However, albuminuria and free hemoglobinuria cause progressive biofilm buildup on the capacitance sensors of the urinometers. The aim of this
Martin Slettengren +2 more
doaj +1 more source