Results 11 to 20 of about 22,402 (256)

Baseline characteristics and disease burden in patients in the International Paroxysmal Nocturnal Hemoglobinuria Registry [PDF]

Haematologica, 2014
Paroxysmal nocturnal hemoglobinuria is a rare, acquired disease associated with hemolytic anemia, bone marrow failure, thrombosis, and, frequently, poor quality of life.
Hubert Schrezenmeier, Petra Muus, Gérard Socié, Jeffrey Szer, Alvaro Urbano-Ispizua, Jaroslaw P. Maciejewski, Robert A. Brodsky, Monica Bessler, Yuzuru Kanakura, Wendell Rosse, Gus Khursigara, Camille Bedrosian, Peter Hillmen   +12 more
doaj   +4 more sources

The prothrombotic state in paroxysmal nocturnal hemoglobinuria: a multifaceted source [PDF]

Haematologica, 2018
Paroxysmal nocturnal hemoglobinuria is a rare acquired hematologic disorder, the most serious complication of which is thrombosis. The increased incidence of thrombosis in paroxysmal nocturnal hemoglobinuria is still poorly understood, but unlike many ...
Barnaby Peacock-Young, Fraser L. Macrae, Darren J. Newton, Anita Hill, Robert A S Ariëns   +4 more
doaj   +2 more sources

Paroxysmal nocturnal hemoglobinuria in systemic lupus erythematosus: a case report [PDF]

Journal of Medical Case Reports, 2011
Introduction Paroxysmal nocturnal hemoglobinuria is an acquired disorder of hemopoiesis and is characterized by recurrent episodes of intravascular hemolysis due to an increased sensitivity to complement-mediated hemolysis.
Nakamura Norio, Sugawara Toshiyuki, Shirato Ken-ichi, Kumasaka Ryuichiro, Nakamura Masayuki, Shimada Michiko, Fujita Takeshi, Murakami Reiichi, Shimaya Yuko, Osawa Hiroshi, Yamabe Hideaki, Okumura Ken   +11 more
doaj   +3 more sources

Percussion hemoglobinuria - a novel term for hand trauma-induced mechanical hemolysis: a case report [PDF]

Journal of Medical Case Reports, 2011
Introduction Extracorpuscular hemolysis caused by mechanical trauma has been well described in relation to lower extremity use, such as in soldiers and runners.
Hariharan Sundaram, Hari Parameswaran N, Cohen Eric P, Bresnahan Barbara A, Vasudev Monica, Vasudev Brahm S   +5 more
doaj   +3 more sources

Case-Control Study of Parturient Hemoglobinuria in Buffaloes [PDF]

Pakistan Veterinary Journal, 2012
Population based case control study of parturient hemoglobinuria was conducted in District Chakwal during April 2009 to January 2011 for quantification of epidemiological risk factors associated with condition.
Altaf Mahmood*, Muhammad Athar Khan, Muhammad Younus1, Muhammad Arif Khan2, Hafiz Javed Iqbal3 and Abdul Ahad4
doaj   +2 more sources

Paroxysmal nocturnal hemoglobinuria clone in 103 Brazilian patients: diagnosis and classification [PDF]

Revista Brasileira de Hematologia e Hemoterapia, 2015
Background: Paroxysmal nocturnal hemoglobinuria is an acquired chronic hemolytic ane- mia, which often manifests as peripheral blood cytopenias and thrombosis. Objective: The aim of this study is to describe a Brazilian population of paroxysmal nocturnal
Ana Paula de Azambuja, Mariester Malvezzi, Marco Antonio Bitencourt, Michel Michels Oliveira, Larissa Alessandra Medeiros, Ricardo Pasquini   +5 more
doaj   +2 more sources

Paroxysmal nocturnal hemoglobinuria and telomere length predicts response to immunosuppressive therapy in pediatric aplastic anemia [PDF]

Haematologica, 2015
Acquired aplastic anemia is an immune-mediated disease characterized by severe defects in stem cell number resulting in hypocellular marrow and peripheral blood cytopenias. Minor paroxysmal nocturnal hemoglobinuria populations and a short telomere length
Atsushi Narita, Hideki Muramatsu, Yuko Sekiya, Yusuke Okuno, Hirotoshi Sakaguchi, Nobuhiro Nishio, Nao Yoshida, Xinan Wang, Yinyan Xu, Nozomu Kawashima, Sayoko Doisaki, Asahito Hama, Yoshiyuki Takahashi, Kazuko Kudo, Hiroshi Moritake, Masao Kobayashi, Ryoji Kobayashi, Etsuro Ito, Hiromasa Yabe, Shouichi Ohga, Akira Ohara, Seiji Kojima   +21 more
doaj   +2 more sources

Evaluating the treatment of patients with paroxysmal nocturnal hemoglobinuria in Brazil: disparities in access and treatment persistence [PDF]

Hematology, Transfusion and Cell Therapy
Background: Paroxysmal nocturnal hemoglobinuria is a rare, life-threatening disease that significantly affects quality of life. Despite therapeutic advances, challenges like treatment burden and limited care access persist.
Rodolfo Delfini Cançado, Paula de Melo Campos, Diego Kashiura, Felipe Thies, Erica Ferreira, Ana Beatriz Machado de Almeida, Lays Paulino Leonel, Lucas Vieira Cortez, Nina Melo, Fabio Fedozzi, Alessandro Bigoni   +10 more
doaj   +2 more sources

Paroxysmal Nocturnal Hemoglobinuria: Diagnostic Challenges in Pediatric Patient

Case Reports in Pediatrics, 2019
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, life-threatening hematologic stem cell disorder characterized by hemoglobinuria, thrombosis, and tendency for bone marrow failure.
Dharshana Krishnaprasadh, Inna Kaminecki, Anna Sechser Perl, Jonathan Teitelbaum   +3 more
doaj   +2 more sources

Paroxysmal Nocturnal Hemoglobinuria: Current Management, Unmet Needs, and Recommendations

Journal of Blood Medicine, 2023
Paroxysmal nocturnal hemoglobinuria (PNH) is an ultra-rare, acquired clonal abnormality, which renders hematopoietic cells exquisitely sensitive to complement-mediated destruction.
Monika Oliver, Christopher J. Patriquin
semanticscholar   +1 more source