Results 101 to 110 of about 41,730 (240)

Functional insights into modulation of BKCa channel activity to alter myometrial contractility [PDF]

, 2014
The large-conductance voltage- and Ca2+-activated K+ channel (BKCa) is an important regulator of membrane excitability in a wide variety of cells and tissues.
England, Sarah K, Lorca, Ramón A, Prabagaran, Monali   +2 more
core   +3 more sources

In the gravid human uterus, oxytocin induces smooth muscle cell contraction via transient receptor potential vanilloid 4 channel activation

The Journal of Physiology, EarlyView.
Abstract figure legend In gravid human uterus smooth muscle, the oxytocin receptor (OXTR) and transient receptor potential vanilloid 4 (TRPV4) calcium channel colocalize at <40 nm by proximity ligation. TRPV4 is necessary for oxytocin‐induced calcium influx and contractility in uterine smooth muscle cells.
Daiana Fornes, Jessica R. Ansari, Guillermina Michel, Cristina M. Alvira, David N. Cornfield   +4 more
wiley   +1 more source

Association between Myometrial Thickness and Assisted Reproductive Technologies Outcomes: A Prospective Cohort Study [PDF]

International Journal of Fertility and Sterility
Background: Myometrial thickness has been expected to be a prognosticator for lower uterine segment function. Anabnormal function of the uterine muscle layer can cause common and important reproductive problems.
Tahereh Madani, Nadia Jahangiri, Seyedeh Masoumeh Moosavisadat, Elaheh Mirzaagha, Saman Maroufizadeh, Shohreh Irani, Firoozeh Ahmadi   +6 more
doaj   +1 more source

Diagnosis and Management of Two Rare Cases of Non‐Puerperal Complete Uterine Inversion

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Non‐puerperal uterine inversion is exceptionally rare and often associated with submucosal or fundal leiomyomas. Its variable presentation frequently delays diagnosis, and distorted pelvic anatomy poses significant surgical challenges. We report two cases of complete non‐puerperal uterine inversion in 44‐year‐old multiparous women presenting ...
Sara Perelmuter, Jeff Feng‐Hsu Lin, Anna Najor, Marc Schiffman, Armen Avetisyan, Ja Hyun Shin   +5 more
wiley   +1 more source

Prostaglandin pathways in equine myometrium regulations: endometrosis progression

Frontiers in Veterinary Science
IntroductionProstaglandins (PG) are important regulators of the myometrial contractility in mammals. Endometrosis, a condition characterized by morphological changes in the equine endometrium, also affects endometrial secretory function.
Katarzyna K. Piotrowska-Tomala, Anna Z. Szóstek-Mioduchowska, Ewa M. Drzewiecka, Ewa M. Drzewiecka, Agnieszka W. Jonczyk, Anna Wójtowicz, Michał H. Wrobel, Graca Ferreira-Dias, Graca Ferreira-Dias, Dariusz J. Skarzynski   +9 more
doaj   +1 more source

Sonographic Reporting Completeness and Sonographic Features of Xanthogranulomatous endometritis: A Systematic Review and Quality Scoring Analysis of Case Reports

Health Science Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background and Aims Xanthogranulomatous endometritis (XGE) is a rare, chronic inflammatory disease that could mimic endometrial malignancy. While ultrasound is a primary imaging tool in gynecology, a comprehensive synthesis of its features in XGE is lacking.
Xiang Ji
wiley   +1 more source

Multifactorial Regulation of Myometrial Contractility During Pregnancy and Parturition

Frontiers in Endocrinology, 2019
The steroid hormones progesterone (P4) and estradiol-17β (E2), produced by the placenta in humans and the ovaries in rodents, serve crucial roles in the maintenance of pregnancy, and the initiation of parturition. Because of their critical importance for
Carole R. Mendelson, Lu Gao, Alina P. Montalbano   +2 more
doaj   +1 more source

Caesarean Scar Ectopic Pregnancy in Early Gestation: A Scoping Review of Definitions and Diagnostic Approach

BJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 5, Page 888-899, April 2026.
ABSTRACT Background Caesarean scar ectopic pregnancy (CSEP) is defined by the implantation and development of a gestational sac inside a caesarean scar defect, but variations in classification systems and diagnostic criteria exist. Objectives This study aimed to systematically review the different criteria used in the medical literature to diagnose ...
Simrit Nijjar, Lucrezia V. De Braud, Ewelina Rogozińska, Cecilia Bottomley, Davor Jurkovic, Eric Jauniaux   +5 more
wiley   +1 more source

Calix[4]arene С-956 selectively inhibits plasma membrane Са(2+),Mg(2+)-АТРase in myometrial cells

The Ukrainian Biochemical Journal, 2018
Using enzymatic assays and kinetic analysis, we demonstrated that 100 µM calix[4]arene C-956 (5,11,17,23-tetra(trifluoro)methyl-(phenylsulfonylimino) methylamino-25,27-dioctyloxy-26,28-dipropoxycalix[4]arene) had the most significant inhibitory effect on
Т. O. Veklich, O. A. Skrabak, Yu. V. Nikonishyna, R. V. Rodik, V. I. Kalchenko, S. O. Kosterin   +5 more
doaj   +1 more source

Senescence‐Driven Remodeling Defines an Aggressive and Immunomodulatory Subtype of Endometriosis

Aging Cell, Volume 25, Issue 4, April 2026.
Senescence in ectopic endometrial cells promotes SASP‐mediated M2 macrophage polarization and enhanced invasiveness of endometriotic lesions. PAK4 drives this process via PI3K/AKT signaling, while stigmasterol suppresses PAK4 and alleviates senescence‐associated immune remodeling. ABSTRACT Endometriosis is a benign yet invasive disease characterized by
Jingchun Liu, Wuyue Han, Jianming Tang, Huanzhi Wan, Haoyu Wang, Jiaxin Peng, Wenjing Ma, Min Hu, Li Hong   +8 more
wiley   +1 more source