Results 21 to 30 of about 182,656 (351)
Current Opinion in Neurology, 2014 Purpose of reviewOur aim is to highlight major advances reported in the last few years in drug-induced muscle toxicity.Recent findingsOur focus is on myopathies induced by statins and immune checkpoint inhibitors with a brief overview of rare steroid myopathies.
Mamatha, Pasnoor +2 more
openaire +3 more sources
Thrombosis Journal, 2021 Background Immune-mediated necrotizing myopathy (IMNM) is characterized by proximal muscle weakness, elvated serum muscle enzyme levels, myopathic electromyography findings, and necrotic muscle fiber with few inflammatory cell infiltration in muscle ...
Jiali Li +5 more
doaj +1 more source
Altered splicing of the BIN1 muscle-specific exon in humans and dogs with highly progressive centronuclear myopathy [PDF]
, 2013 Amphiphysin 2, encoded by BIN1, is a key factor for membrane sensing and remodelling in different cell types. Homozygous BIN1 mutations in ubiquitously expressed exons are associated with autosomal recessive centronuclear myopathy (CNM), a mildly ...
A Buj-Bello +58 more
core +7 more sources
Aquaporin-4 expression in distal myopathy with rimmed vacuoles
BMC Neurology, 2012 Background Distal myopathy with rimmed vacuoles/hereditary inclusion body myopathy is clinically characterized by the early involvement of distal leg muscles. The striking pathological features of the myopathy are muscle fibers with rimmed vacuoles.
Hoshi Akihiko +5 more
doaj +1 more source
A Systematic Review and Meta-Analysis of the Prevalence of Congenital Myopathy
Frontiers in Neurology, 2021 Background: Congenital myopathy constitutes a heterogeneous group of orphan diseases that are mainly classified on the basis of muscle biopsy findings. This study aims to estimate the prevalence of congenital myopathy through a systematic review and meta-
Kun Huang +3 more
doaj +1 more source
A Case of Statin-Associated Autoimmune Myopathy. [PDF]
, 2017 A 70-year-old previously independent man developed progressive proximal leg weakness resulting in a fall at home suffering traumatic brain injury. He was prescribed a statin medication two years prior, but this was discontinued on admission to the ...
Dokukin, Andrei N +6 more
core +3 more sources
A rare structural myopathy: nemaline myopathy [PDF]
Türk Pediatri Arşivi, 2018 Nemaline myopathy, which is characterized by the accumulation of ''rod'' bodies in muscle fibers is a very rare inherited muscle disease. According to the underlying mutation, the disease has varying severity of clinical outcomes. Patients with severe forms of the disease die because of hypotonia, feeding difficulties, aspiration pneumonia, and ...
Yeşilbaş, Osman +7 more
openaire +2 more sources
Chloroquine and Hydroxychloroquine Myopathy: Clinical Spectrum and Treatment Outcomes
Frontiers in Neurology, 2021 Chloroquine (CQ) and hydroxychloroquine (HCQ) have been associated with muscle toxicity, mostly described as a proximal myopathy with evidence of lysosomal dysfunction on muscle biopsy.
Elie Naddaf +2 more
doaj +1 more source
Journal of the Saudi Heart Association, 2019 A well-known side effect of statin therapy is myopathy. We report a case of statin induced necrotizing autoimmune myopathy, a rare variant of statin-induced myopathy. A 64-year-old gentleman on atorvastatin presented with muscle weakness.
Yehia Saleh +3 more
doaj +1 more source
The prediction of the development of diabetic myopathy in children with type 1 diabetes mellitus
Zdorovʹe Rebenka, 2021 Background. The purpose was to determine the frequency, risk factors of the development of diabetic myopathy in children with type 1 diabetes mellitus (DM1), and to create a mathematical model for predicting the formation of pathology.
O.Ye. Pashkova, N.I. Chudova
doaj +1 more source