Results 101 to 110 of about 194,647 (228)

Detecting Glaucoma in Highly Myopic Eyes From Fundus Photographs Using Deep Convolutional Neural Networks

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background High myopia (HM) is a major risk factor for glaucoma. However, glaucomatous optic neuropathy is often undiagnosed owing to atypical structural alterations with axial elongation. Moreover, an algorithm to detect glaucoma in highly myopic eyes has not yet been reported.
Xiaohong Chen, Chen Zhou, Yingting Zhu, Man Luo, Lingjing Hu, Wenjing Han, Chengguo Zuo, Zhidong Li, Hui Xiao, Shaofen Huang, Xuhao Chen, Xiujuan Zhao, Lin Lu, Yizhou Wang, Yehong Zhuo   +14 more
wiley   +1 more source

Current Definition and Classification of Pathologic Myopia

Güncel Retina Dergisi (Current Retina Journal)
Pathologic myopia is one of the leading causes of vision loss. Although there is comprehensive literature on pathologic myopia, there is confusion regarding its definition and classification. In this paper, the difference in definition between pathologic
Esat Yetkin
semanticscholar   +1 more source

The role of the Wnt/β-catenin signaling pathway in the development of myopia [PDF]

, 2015
近视是一种常见的屈光不正。高度近视则可能伴随各种严重的并发症，甚至致盲。近视发生发展的机制迄今不清，目前也无法有效的防治。因此，近视发生发展的机制一直是眼科学研究的重要课题之一。本论文通过对近视发生过程中的基础研究，探讨近视发生的机制，以发现新的药物靶点及寻求治疗近视的新途径。 多巴胺D2受体（DopamineD2receptors,D2R）在调控眼球的屈光发育中发挥重要作用，但其具体的作用机制尚不清楚。我们考虑DA/D2R可能是通过调控下游的信号通路来发挥作用。在本论文中，我们用小鼠形觉剥夺近视 ...
刘真
core  

Conjunctival ultraviolet autofluorescence as a biomarker of outdoor exposure in myopia: a systematic review and meta-analysis

Scientific Reports
Outdoor exposure is considered the primary modifiable risk factor in preventing the development of myopia. This effect is thought to be attributed to the light-induced synthesis and release of dopamine in the retina.
Natali Gutierrez Rodriguez, Aura Ortega Claici, Jorge A. Ramos-Castaneda, Jorge González-Zamora, Valentina Bilbao-Malavé, Miriam de la Puente, Patricia Fernandez-Robredo, Sandra Johanna Garzón-Parra, Manuel Garza-Leon, Sergio Recalde   +9 more
doaj   +1 more source

Antioxidative status as assessed by enzymatic activity in the tear fluid and by the levels of sulfur-containing protein groups in the blood and tear fluid of myopes before and after treatment with a thiol agent

Journal of Ophthalmology, 2017
Background: Myopia remains a leading cause of vision loss and visual disability in Ukraine (75%) and one of the most common ocular disorders worldwide. Most of available biological materials like blood and tear fluid can be used to measure the levels of ...
E.I. Surova, I.M. Boichuk, S.G. Kolomiichuk   +2 more
doaj   +1 more source

Monogenic Retinal Diseases Associated With Genes Encoding Phototransduction Proteins: A Review

Clinical &Experimental Ophthalmology, Volume 53, Issue 3, Page 260-280, April 2025.
ABSTRACT Phototransduction, the process by which captured photons elicit electrical changes in retinal rod and cone cells, represents the first neuronal step in vision and involves interactions between several highly specialised proteins. Pathogenic variants in genes encoding many of these proteins can give rise to significant vision impairment ...
Wendy M. Wong, Omar A. Mahroo
wiley   +1 more source

Efektivitas Penyuluhan Rabun Jauh (Miopia) Terhadap Tingkat Pengetahuan Siswa Kelas VI SD Islam Al-azhar 21 Kecamatan Pontianak Tenggara Tahun 2014 [PDF]

, 2014
Background: Visual acuity is the primary indicator for healthy eye. Visual acuity will decrease if there is a process that impaires reflective media in the eye. Myopia is a type of refractive disorders that is common in school-age population.
Putri, D. E. (Dwi)
core  

Association of High Myopia with Crystallin Beta A4 (CRYBA4) Gene Polymorphisms in the Linkage-Identified MYP6 Locus [PDF]

, 2012
Background: Myopia is the most common ocular disorder worldwide and imposes tremendous burden on the society. It is a complex disease. The MYP6 locus at 22 q12 is of particular interest because many studies have detected linkage signals at this interval.
Fung, WY, Ho, DWH, Ng, PW, Yap, MKH, Yip, SP   +4 more
core   +1 more source

Safety of an Intravitreal Bevacizumab Biosimilar (MVASI)

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background Intravitreal bevacizumab has been used off‐label to treat multiple ocular conditions for almost two decades. Reference bevacizumab, Avastin, was discontinued in Australia in 2021. A bevacizumab biosimilar, MVASI, was approved by the Therapeutic Goods Administration for the treatment of metastatic cancer in 2020.
Hanru Wang, Bobak Bahrami, Sonia Huang, Marzieh Tahmasebi Sarvestani, Sudha Cugati, Stewart Lake, Weng Onn Chan, Devaraj Supramaniam, Matthew Little   +8 more
wiley   +1 more source

Changes in Vitreous and Retina in Pathological Myopia

Güncel Retina Dergisi (Current Retina Journal)
Myopia is the leading cause of visual impairment and its prevalence continues to increase significantly. Pathological myopia affects 1-3% of the general population and is one of the main causes of low vision and blindness worldwide.
M. Çıtırık
semanticscholar   +1 more source