Results 71 to 80 of about 49,142 (262)

Calcitriol inhibits ROS-NLRP3-IL-1β signaling axis via activation of Nrf2-antioxidant signaling in hyperosmotic stress stimulated human corneal epithelial cells

Redox Biology, 2019
Purpose: The activation of ROS-NLRP3-IL-1β signaling axis induced by hyperosmotic stress (HS) has been recognized as a key priming stage of epithelial inflammation in dry eye pathogenesis.
Yiqin Dai, Jing Zhang, Jun Xiang, Yue Li, Dan Wu, Jianjiang Xu   +5 more
doaj   +1 more source

Autonomous Leadership: How Board Independence Shapes Machine Learning Based Corporate Culture in Thailand

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Corporate culture is a critical driver of corporate social responsibility, shaping how firms internalize sustainability, social and environmental concerns, yet its governance antecedents are less understood. Motivated by the need to understand how governance structures affect organizational values and behavior, we explore the relationship ...
Sirimon Treepongkaruna, Stefano Starita
wiley   +1 more source

Policymakers' Perceptions of the Use of Deliberative Mini‐Publics to Support Sustainability Policies

Environmental Policy and Governance, EarlyView.
ABSTRACT Deliberative mini‐publics (DMPs) have emerged as a novel method to deepen public participation in complex and contentious policy decisions, such as those related to sustainability transformations. Despite an increasing interest in applying DMPs in environmental governance, little is known about policymakers' expectations regarding their ...
Heli Saarikoski, Maria Ojanen, Mikael Hildén, Hanna Mela, Suvi Huttunen, Katariina Kulha, Katriina Soini, Jaana Sorvali   +7 more
wiley   +1 more source

Corneal epithelial aberrations: a novel diagnostic tool for keratoconus and forme fruste keratoconus

Eye and Vision
Purpose To assess the ability of corneal epithelial aberrations to discriminate forme fruste keratoconus (FFKC) and keratoconus (KC) from normal eyes.
Rui Ning, Chak Seng Lei, Xinning Yang, Yue Li, Yizhou Yang, Ingemar Gustafsson, Giacomo Savini, Domenico Schiano-Lomoriello, Xingtao Zhou, Xiaoying Wang, Jinhai Huang   +10 more
doaj   +1 more source

Nature‐Based Solutions for Climate Adaptation: Review of Barriers to Adoption and Guidelines for Policymakers

Environmental Policy and Governance, EarlyView.
ABSTRACT Nature‐based solutions (NBS) for climate adaptation encompass a range of approaches that work with nature to increase resilience to climate change while providing ecological, economic and social co‐benefits. These solutions have frequently been put forward for application in urban contexts, such as the creation of urban forests, but can ...
Anita Vollmer, Stefano Ceolotto, Niall Farrell   +2 more
wiley   +1 more source

Data on corneal proteome and differentially expressed corneal proteins in highly myopic chicks using a data independent quantification approach

Data in Brief, 2019
Myopia is an abnormal refractive status, explained by an excessive ocular lengthening mostly in posterior segments. Although growing evidence of anterior segments, specifically altered corneal geometries with biomechanical properties in myopes have been ...
Byung Soo Kang, Thomas Chuen Lam, Jimmy Ka-Wai Cheung, King Kit Li, Chea-Su Kee   +4 more
doaj   +1 more source

How Changing Narratives About the Future Shape Policymaking for the Long Term

European Policy Analysis, EarlyView.
ABSTRACT How can we explain decisions by governments to engage in policy investments—accepting short‐term costs in return for anticipated gains in the longer term—after previously sustaining the status quo? Our article examines the role of narratives in changing expectations about the future as a key driver of intertemporal policymaking. In light of an
Pieter Tuytens, Charlotte Haberstroh
wiley   +1 more source

Epilepsy characteristics in patients with muscle‐eye‐brain disease: A systematic review of electroclinical features

Epileptic Disorders, EarlyView.
Abstract Background and Objectives Muscle‐Eye‐Brain disease (MEB) is a dystroglycanopathy that belongs to the congenital muscular dystrophies. Central nervous system manifestations include congenital brain abnormalities, neurodevelopmental delay, and epilepsy, making it a rare but important cause of developmental and epileptic encephalopathy.
Stefania Kalampokini, Evripidis Pityrigkas, Eleni Liouta, Georgia Pepe, Vasiliki Poulidou, Martha Spilioti, Vasilios K. Kimiskidis   +6 more
wiley   +1 more source

Sex‐specific elevated incidence of glaucoma associated with topiramate versus valproate or lamotrigine in epilepsy, not migraine: A population‐based cohort study

Epilepsia, EarlyView.
Abstract Objective Topiramate has been linked to increased glaucoma risk, potentially through mechanisms involving ocular fluid shifts. However, comparative risks vs other antiseizure medications (ASMs) and variation by sex or indication remain uncertain.
Cuiling Wei, Rachel Yui Ki Chu, Rachel Lancey Lai, Florinda Hui‐Ning Chu, Ian Yu Hin Leung, William Chun Yin Leung, Franco Wing Tak Cheng, Thomas Chi Ho Lam, Ian Chi Kei Wong, Esther Wai Yin Chan, Francisco Tsz Tsun Lai   +10 more
wiley   +1 more source

The effects of fixation stability, corneal density, and epithelial hyperplasia on the efficacy of astigmatism correction by transepithelial photorefractive keratectomy

Eye and Vision
Background Transepithelial photorefractive keratectomy (transPRK) can be safely and predictably performed to correct low-to-high astigmatism. This study explored the effects of fixation stability, corneal density (CD), ocular residual astigmatism (ORA ...
Junjie Yu, Hao Zhou, Minjie Chen, Zhiqiang Yu, Xingtao Zhou, Yishan Qian   +5 more
doaj   +1 more source