Results 51 to 60 of about 77,565 (310)

Impact of Parental History of Myopia on the Development of Myopia in Mainland China School-Aged Children

open access: yes, 2014
Background Myopia is a very common condition and a significant public health problem in China. The objective of the study was to explore the genetic influence on myopia in Mainland China school-aged children in Beijing.
Elliott Y. Ah-kee   +5 more
core   +1 more source

Deconstruction of Human Age‐Related Cataract Capsules Defines Aging

open access: yesAdvanced Science, EarlyView.
We generate a comprehensive atlas of age‐related cataracts (ARC) at a single‐cell resolution, encompassing three disease states—mild cataract group (Mild), severe cortical cataract group (Severe_C), and severe nuclear cataract group (Severe_N). We find that ARC involves seven distinct lens capsule cell types, with notable differences in cellular ...
Qiaomei Tang   +9 more
wiley   +1 more source

CLRe: A Synergistic Dual‐Engine Framework for One‐Step Retrosynthesis Prediction

open access: yesAdvanced Science, EarlyView.
CLRe uses a contrastive difficulty score to order pretrained seq2seq fine‐tuning for retrosynthesis. Reaction embeddings define the ranking score, and a cumulative easy‐to‐hard schedule expands from the easiest subset to the full training set while earlier examples remain active.
Tianhao Su   +5 more
wiley   +1 more source

Towards a Compositional Framework for Describing Human Phenotypes

open access: yesAdvanced Science, EarlyView.
The Phenotype Assembly Method (PhenoAM) decomposes phenotype variables into measurable Features and typed Qualifiers, enabling standardized, machine‐readable Phenome Data Elements (PhenoDEs) that preserve measurement context. Applied in the International Human Phenome Project (IHPP), the framework yields 58 371 PhenoDEs and supports component‐level ...
Wanting Hu   +11 more
wiley   +1 more source

Risk factors for myopia: Putting causal pathways into a social context

open access: yes, 2020
© The Editor(s) (if applicable) and The Author(s) 2020. Myopia is often described as resulting from a complex set of interactions between genetic and environmental risk factors.
Morgan, IG, French, AN, Rose, KA
core   +1 more source

Exploiting Edge Semantics in Job Shop Scheduling Problem With Heterogeneous Graph Transformers

open access: yesAdvanced Intelligent Systems, EarlyView.
A heterogeneous graph transformer (HGT) is introduced for reinforcement learning‐based job shop scheduling by explicitly distinguishing precedence and machine‐contention relations through edge‐type‐specific attention. The proposed framework learns richer scheduling representations, improves decision quality over homogeneous graph models, and highlights
Bulent Soykan, Fatih Kasimoglu
wiley   +1 more source

TGFBI Gene Mutation Analysis of Clinically Diagnosed Granular Corneal Dystrophy Patients Prior to PTK: A Pilot Study from Eastern China

open access: yesScientific Reports, 2017
This study investigated the TGFBI gene mutation types in outpatients clinically diagnosed with granular corneal dystrophy (GCD) prior to phototherapeutic keratectomy (PTK), also calculated the mutation rate of subjects with normal corneas, but positive ...
Li Zeng   +8 more
doaj   +1 more source

Refractive outcomes and optical quality after implantation of posterior chamber phakic implantable collamer lens with a central hole (ICL V4c)

open access: yesBMC Ophthalmology, 2018
Background To investigate refractive outcomes and optical quality after implantation of posterior chamber phakic implantable collamer lens with a central hole (ICL V4c) to correct high myopia. Methods Sixty seven eyes of 38 patients who underwent ICL V4c
Huamao Miao   +5 more
doaj   +1 more source

Pathologic Myopia

open access: yesAsia-Pacific Journal of Ophthalmology, 2016
Pathologic myopia (PM) is the only myopia that causes the loss of best-corrected visual acuity. The main reason for best-corrected visual acuity loss is complications specific to PM, such as myopic maculopathy, myopic traction maculopathy, and myopic optic neuropathy (or glaucoma).
openaire   +4 more sources

The Herfindahl neutral point: A firm‐level threshold for managing market concentration with evidence from US hog packing

open access: yesAmerican Journal of Agricultural Economics, EarlyView.
Abstract This paper derives a firm‐level threshold, the Herfindahl Neutral Point, from the standard concentration index used in merger review. At this threshold, a marginal expansion leaves the index unchanged. Firms below the threshold reduce concentration when they expand; firms above it increase concentration.
Andrew J. Keller, Krishna P. Paudel
wiley   +1 more source

Home - About - Disclaimer - Privacy