Results 31 to 40 of about 51,161 (263)

Agreement between a new optical low coherence reflectometry biometer and an anterior segment optical coherence tomographer

Eye and Vision, 2023
Background To assess agreement of measurements between a new optical low coherence reflectometry (OLCR) biometer (SW-9000, Suoer, Tianjin, China) and a spectral-domain optical coherence tomographer (SD-OCT)/Placido topographer (MS-39, CSO, Florence ...
Yiran Wang, Ting Wan, Luze Liu, Yuyuan Xue, Xinyao Chen, Giacomo Savini, Domenico Schiano-Lomoriello, Xingtao Zhou, Jinjin Yu, Jinhai Huang   +9 more
doaj   +1 more source

MAM‐Localized MANF Counteracts Microinflammatory Stress to Attenuate Mitochondrial Dysfunction and Cataractogenesis in High Myopia

Advanced Science, EarlyView.
Chronic microinflammation in high myopia suppresses MANF in lens epithelial cells. MANF normally resides within MAMs and promotes ubiquitin‐mediated degradation of the ER Ca2+ pump SERCA2. MANF loss causes pathological SERCA2 accumulation, MAM hyperassembly, and disrupted ER‐to‐mitochondria Ca2+ transfer, leading to mitochondrial failure, oxidative ...
Xin Liu, Hao Li, Ching Kang, Dongling Guo, Shuyu Liu, Jiaqi Meng, Zhiqian Huang, Yu Du, Xiangjia Zhu   +8 more
wiley   +1 more source

TGFBI Gene Mutation Analysis of Clinically Diagnosed Granular Corneal Dystrophy Patients Prior to PTK: A Pilot Study from Eastern China

Scientific Reports, 2017
This study investigated the TGFBI gene mutation types in outpatients clinically diagnosed with granular corneal dystrophy (GCD) prior to phototherapeutic keratectomy (PTK), also calculated the mutation rate of subjects with normal corneas, but positive ...
Li Zeng, Jing Zhao, Yingjun Chen, Feng Zhao, Meiyan Li, Connie Chao-Shern, Tara Moore, John Marshall, Xingtao Zhou   +8 more
doaj   +1 more source

Model‐Based Bayesian Optimization for Organic Photovoltaics: Combining Bayesian Optimization With Physical Domain Knowledge

Advanced Energy Materials, EarlyView.
Integration of a physical solar cell model into Bayesian optimization is performed using the Knowledge Gradient acquisition function to balance exploration and exploitation. Experimental validation on the PTQ10:BTP‐eC9 material system and statistical validation on an OPV benchmark function show that the model‐based approach outperforms conventional ...
Leonard Christen, Thomas Kirchartz
wiley   +1 more source

Refractive outcomes and optical quality after implantation of posterior chamber phakic implantable collamer lens with a central hole (ICL V4c)

BMC Ophthalmology, 2018
Background To investigate refractive outcomes and optical quality after implantation of posterior chamber phakic implantable collamer lens with a central hole (ICL V4c) to correct high myopia. Methods Sixty seven eyes of 38 patients who underwent ICL V4c
Huamao Miao, Xun Chen, Mi Tian, Yingjun Chen, Xiaoying Wang, Xingtao Zhou   +5 more
doaj   +1 more source

Pathologic Myopia

Asia-Pacific Journal of Ophthalmology, 2016
Pathologic myopia (PM) is the only myopia that causes the loss of best-corrected visual acuity. The main reason for best-corrected visual acuity loss is complications specific to PM, such as myopic maculopathy, myopic traction maculopathy, and myopic optic neuropathy (or glaucoma).
openaire   +4 more sources

Epidemiology of myopia [PDF]

Eye, 2014
Myopia is one of the most prevalent disorders of the eye. Higher myopia is associated with comorbidities that increase risks of severe and irreversible loss of vision, such as retinal detachment, subretinal neovascularization, dense cataract, and glaucoma.
P J, Foster, Y, Jiang
openaire   +2 more sources

Advanced Experiment Design Strategies for Drug Development

Advanced Intelligent Discovery, EarlyView.
Wang et al. analyze 592 drug development studies published between 2020 and 2024 that applied design of experiments methodologies. The review surveys both classical and emerging approaches—including Bayesian optimization and active learning—and identifies a critical gap between advanced experimental strategies and their practical adoption in ...
Fanjin Wang, Anthony Harker, Mohan Edirisinghe, Maryam Parhizkar   +3 more
wiley   +1 more source

Peripapillary Vascular Reactivity in Primary Open-Angle Glaucoma With High Myopia by Using Optical Coherence Tomography Angiography

Frontiers in Medicine, 2022
PurposeTo evaluate peripapillary vascular reactivity in primary open-angle glaucoma (POAG) with and without high myopia (HM) by using optical coherence tomography angiography (OCTA).MethodsThis prospective study enrolled 48 eyes with POAG, including 16 ...
Xintong Fan, Xintong Fan, Xintong Fan, Xintong Fan, Huan Xu, Huan Xu, Huan Xu, Huan Xu, Ruyi Zhai, Ruyi Zhai, Ruyi Zhai, Ruyi Zhai, Qilian Sheng, Qilian Sheng, Qilian Sheng, Qilian Sheng, Yanan Sun, Yanan Sun, Yanan Sun, Yanan Sun, Tingting Shao, Tingting Shao, Tingting Shao, Tingting Shao, Xiangmei Kong, Xiangmei Kong, Xiangmei Kong, Xiangmei Kong   +27 more
doaj   +1 more source

The Herfindahl neutral point: A firm‐level threshold for managing market concentration with evidence from US hog packing

American Journal of Agricultural Economics, EarlyView.
Abstract This paper derives a firm‐level threshold, the Herfindahl Neutral Point, from the standard concentration index used in merger review. At this threshold, a marginal expansion leaves the index unchanged. Firms below the threshold reduce concentration when they expand; firms above it increase concentration.
Andrew J. Keller, Krishna P. Paudel
wiley   +1 more source