Results 131 to 140 of about 933,148 (275)

Artificial Intelligence for Identifying Tumor‐Reactive CD8+ T Cells: Biological Principles, Computational Advances, and Future Directions

Med Research, EarlyView.
This review details a three‐stage paradigm shift for tumor‐reactive CD8+ T‐cell identification: decoding transcriptomic states, deciphering clonal functional efficacy, and molecular‐level therapeutic TCR design. Addressing translational hurdles and generative AI “scientific blind spots”—such as missing catch bonds—we present a visionary roadmap.
Chao Yang, Yingying Sun, Yan Zhang, Yifen Shi, Zhiwen Shi   +4 more
wiley   +1 more source

Advancing Artificial Intelligence in Myopia Management: From Predicting Progression to Supporting Clinical Decisions

Med Research, EarlyView.
The AI‐enabled multimodal framework for whole‐life myopia management. Graphical abstract illustrates the transition of myopia care from premyopia to myopia, high myopia, and pathologic myopia. Multimodal data, including demographic and refractive information, genetic, behavioral and environmental factors, ophthalmic imaging, and omics profiles, can be ...
Zewei Zhang, Yun Wang, Lifei Zhang, Dongmei Chen, Weijie Zhang, Fang Li, Jibo Zhou   +6 more
wiley   +1 more source

School-level prediction and management of myopia in children and adolescents

Journal of Translational Medicine
Background Previous Artificial Intelligence (AI) models are mainly based on hospital data to predict myopia progression in myopic children. However, school-level AI models for predicting myopia onset in non-myopic children are lacking.
Shengsong Xu, Linling Li, Yingting Zhu, Zhenbang Ruan, Yiwen Qu, Zhuandi Zhou, Yin Hu, Zhidong Li, Fei Hou, Xiaohua Zhuo, Yunxia Leng, Xuelin Huang, Yamei Lu, Zhirong Wang, Shuifeng Deng, Yehong Zhuo, Guoming Zhang, Min Fu, Xiao Yang   +18 more
doaj   +1 more source

Sustainable Healthy Diet Transitions: An Examination of Media Discourse Concerning Beef in the United Kingdom From 2018 to 2022

Sustainable Development, EarlyView.
ABSTRACT The role of diet in individual and planetary health is increasingly scrutinised as consumers are encouraged to make food choices that balance health and sustainability, particularly with beef. While prior research has considered reduction from the perspective of alternate product acceptance, the social context of beef is less understood. Media
Sean Tanner, Mary McCarthy, David Giles
wiley   +1 more source

From Waste to Value: A Data‐Driven Framework for Sustainable Raw Materials Substitution in the Ceramic Industry

Sustainable Development, EarlyView.
ABSTRACT With increasing geopolitical risks, environmental pressures, and regulatory demands, the sustainable sourcing of raw materials has become a global priority for achieving the United Nations Sustainable Development Goals (SDGs), particularly SDG 9 (Industry, Innovation and Infrastructure), SDG 12 (Responsible Consumption and Production), and SDG
Francesco Parisi, Luciana Randazzo, Davide Settembre Blundo, Isabella Ganci, Silvestro Antonio Ruffolo, Mauro Francesco La Russa   +5 more
wiley   +1 more source

Sustainable Business Models and Environmental Innovation Capacity: The Moderating Role of Board Effectiveness

Sustainable Development, EarlyView.
ABSTRACT Sustainable Business Models (SBMs) reflect the degree to which sustainability principles are embedded across firms' business model architectures. However, the mere adoption of these models does not guarantee improvements in environmental innovation capacity due to internal organizational inertia.
Emma García‐Meca, Jennifer Martínez‐Ferrero, Christian Nielsen   +2 more
wiley   +1 more source

Visionary, engineer, and experimenter: Three forms of entrepreneurship in the quest for product–market fit

Strategic Entrepreneurship Journal, EarlyView.
Abstract Research summary Entrepreneurship unfolds under uncertainty, which complicates entrepreneurs' efforts to align idea, action, and environment to reach product–market fit. To illuminate how entrepreneurs perform such alignment, we complement the theory‐based view and its focus on cognitive uncertainty with a discussion of behavioral uncertainty.
Thomas Zellweger, Djordje Djokovic
wiley   +1 more source

Are client ties pre‐entry resources? Performance implications of client tie diversification

Strategic Management Journal, EarlyView.
Abstract Research Summary This study investigates client tie diversification, where firms enter markets with existing clients. Recognizing the theoretical basis for both positive and negative performance implications, the paper adopts a question‐driven approach and discovers a strong negative correlation between client tie diversification and firm ...
Heejung Byun
wiley   +1 more source

Better on Average? Average Inflation Targeting With an Unclear Averaging Window

Southern Economic Journal, EarlyView.
ABSTRACT Average inflation targeting (AIT) aims to stabilize inflation expectations by offsetting past deviations from target. However, ambiguity about the averaging window can complicate expectations formation and reduce policy effectiveness. This paper integrates AIT into a benchmark DSGE model, incorporating adaptive learning and a signal extraction
James Dean
wiley   +1 more source

DQN‐Guided Subset‐Induced OCSVM Kernel Approximation for Imbalanced Anomaly Detection

IEEJ Transactions on Electrical and Electronic Engineering, EarlyView.
Anomaly detection under limited normal data remains a fundamental challenge due to severe class imbalance and scarcity of anomalies. We propose a novel framework that reformulates support vector selection in One‐Class SVM as a sequential decision‐making problem.
Wenqian Yu, Jiaying Wu, Jinglu Hu
wiley   +1 more source