Results 51 to 60 of about 29,563 (153)

CRB1‐Associated Inherited Retinal Dystrophies: Prospective Natural History Study With 4 Years of Follow‐Up

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background The lack of validated and sensitive clinical endpoints remains a major challenge in the design of gene therapy trials for inherited retinal dystrophies (IRDs). This prospective longitudinal cohort study describes the natural disease progression of IRDs caused by pathogenic mutations in the Crumbs homologue 1 (CRB1) gene, and ...
Jessica S. Karuntu, Xuan‐Thanh‐An Nguyen, Mays Talib, Mary J. van Schooneveld, Jan Wijnholds, Maria M. van Genderen, Jos Twisk, Nicoline E. Schalij‐Delfos, Caroline C. W. Klaver, Ralph J. Florijn, Jacoline B. ten Brink, Magda A. Smoor, L. Ingeborgh van den Born, Carel B. Hoyng, Alberta A. H. J. Thiadens, Camiel J. F. Boon   +15 more
wiley   +1 more source

Macular choroidal volume variations in highly myopic eyes with myopic traction maculopathy and choroidal neovascularization

, 2014
PURPOSE:: To compare the choroidal volume (CV) between emmetropic and highly myopic eyes, and to assess if the presence of myopic fundus abnormalities, myopic traction maculopathy, or choroidal neovascularization affects the CV.
G. Barteselli, H. Hou, J. Chhablani, F. Ma, D. U. Bartsch, L. Conner, S. El Emam, S. N. Lee, L. Cheng, W. R. Freeman   +9 more
core   +1 more source

Low‐Dose Atropine for Myopia Control in Children: A Comprehensive Review With Indian Evidence

Eye &ENT Research, Volume 3, Issue 3, Page 118-124, September 2026.
ABSTRACT Myopia is an increasingly prevalent public health concern in India, particularly among school‐aged children in urban and academically demanding environments. Early‐onset myopia is associated with rapid progression and an increased lifetime risk of vision‐threatening complications such as retinal detachment, myopic maculopathy, glaucoma, and ...
Ragni Kumari
wiley   +1 more source

Whole‐Exome Sequencing Identifies Novel CPAMD8 Variants in Congenital Cataract and Candidate Variants in Pathologic Myopia

Molecular Genetics &Genomic Medicine, Volume 14, Issue 9, September 2026.
Whole‐exome sequencing identified compound heterozygous CPAMD8 variants supporting a congenital cataract phenotype in one family and candidate CPAMD8 variants in a second family with pathologic myopia, highlighting the need for segregation and functional validation.
Qiu‐ling Xie, Qiao Wang, Yanan Liu, Teng Huang, Jin Li   +4 more
wiley   +1 more source

High Myopia: A Hospital-Based Study of The Clinical Profile and Visual Impairment

Delhi Journal of Ophthalmology, 2020
Introduction: High axial myopia is an increasingly common refractive error leading to retinal degeneration and visual impairment. Objective: To study the clinical profile and visual impairment in high myopia presenting to a teaching hospital.
Rejitha Chinnu Varghese, Uma Kulkarni
doaj   +1 more source

Emerging Technologies for the Management and Mitigation of Myopia Progression: A Scoping Review

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Currently, myopia affects approximately 1,406 million individuals, representing 22.9% of the global population. Emerging technologies are transforming eye care by providing innovative approaches to address the global challenge of myopia progression.
Kingsley Ekemiri, Khathutshelo Percy Mashige, Diane B. van Staden, Katie Connolly, Okechi Ulumma Amaechi, Esther Daniel, Tiwabwork Tekalign   +6 more
wiley   +1 more source

Correlation of morphological characteristics of staphyloma with the structural and functional outcomes of myopic traction maculopathy after macular buckle surgery

Indian Journal of Ophthalmology, 2021
Purpose: To compare morphological features of staphyloma (type and grade) with structural and functional outcomes in 11 patients with symptomatic myopic tractional maculopathy (MTM) who underwent macular buckle surgery.
Gitanjli Sood, Pradeep Susvar
doaj   +1 more source

Three-Dimensional Eye Shape, Myopic Maculopathy, and Visual Acuity: The Zhongshan Ophthalmic Center-Brien Holden Vision Institute High Myopia Cohort Study [PDF]

, 2017
PURPOSE To investigate the relationship among eye shape, myopic maculopathy, and visual acuity in highly myopic eyes using 3-dimensional (3D) magnetic resonance imaging (MRI). DESIGN Observational case series.
Ou Xiao, Morgan, Ian G, Wu, Huawang, Chen, Linxing, Huawang Wu, Mingguang He, Linxing Chen, Guo, Xinxing, Xiao, Ou, He, Mingguang, Yanxian Chen, Xinxing Guo, Chen, Yanxian, Ian G. Morgan   +13 more
core   +1 more source

Neovascular age‐related macular degeneration without drusen

Acta Ophthalmologica, Volume 104, Issue 3, Page e300-e311, May 2026.
Abstract Purpose To describe the clinical characteristics and 1‐year follow‐up of patients with neovascular AMD (nAMD) without drusen in either eye. Methods This is a multicentre retrospective cohort study in three tertiary referral centres in The Netherlands. We included patients of 55 years or older with nAMD in one or both eyes, without the presence
Marc J. Sirks, Elon H. C. van Dijk, Husein Ghalayini, Somayeh Bazdar, WeiFeng Yu, Suzanne Yzer, José P. Martinez Ciriano, Reinier O. Schlingemann, Roselie M. H. Diederen, Camiel J. F. Boon   +9 more
wiley   +1 more source

Incidence, risk factors, and outcomes of numerical hypotony and choroidal effusion following PRESERFLO MicroShunt implantation

Acta Ophthalmologica, Volume 104, Issue 3, Page e239-e250, May 2026.
Abstract Purpose To evaluate the incidence, outcomes, and risk factors of numerical hypotony (NH) and choroidal effusion (CE) following standalone PRESERFLO MicroShunt (PMS) implantation. Methods Primary open‐angle glaucoma (POAG) and pseudoexfoliative glaucoma (PXG) patients with uni‐ or bilateral surgery at a tertiary university hospital were ...
Emil Nasyrov, Isabel Kommerell, Isabell Schleicher, David A. Merle, Caroline J. Wenzel, Bogomil Voykov   +5 more
wiley   +1 more source