Results 91 to 100 of about 32,263 (310)

The effect of Endurance Exercise on myh6 Gene Expression and Structural and Functional Changes of Left Ventricular

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2016
Background and Objectives: Endurance exercise induces cardiac remodeling. Also, myh6 gene is affected by cardiac remodeling. This study was performed with the objective of determining the effect of endurance activity on cardiac myh6 gene expression ...
Mohammad Fathi
doaj  

Role of myosin heavy chains in adaptive and pathological processes – a systematic review

Quality in Sport
Introduction: Myosin heavy chains (MHCs) are the core group of proteins that builds skeletal and cardiac muscle. Their characteristic is determined depending on MHC isoform, its percentage distribution and cross-sectional area of fibers it builds. These
Tomasz Busłowicz, Anna Kler, Aleksandra Grzesica, Martyna Malerczyk, Dagmara Gaweł-Dąbrowska   +4 more
doaj   +1 more source

Voluntary exercise and testosterone therapy caused increase in percentage of Myh6 and expression of oxidative stress marker Cybb in left ventricles of rats

European Pharmaceutical Journal, 2016
Aim: The aim of this study is to identify a possible damage to heart ventricles caused by supraphysiological doses of testosterone, voluntary physical activity or their combination.
Radik M., Doka G., Malikova E., Krenek P., Klimas J.   +4 more
doaj   +1 more source

Heavy and light roles: myosin in the morphogenesis of the heart [PDF]

, 2012
Myosin is an essential component of cardiac muscle, from the onset of cardiogenesis through to the adult heart. Although traditionally known for its role in energy transduction and force development, recent studies suggest that both myosin heavy-chain ...
A Abu-Daya, A Du, A Horowitz, A Houmeida, A Wessels, AA Lagrutta, AE Chambers, AN Tullio, AS Warkman, AV Postma, B Brenner, BA Danowski, BG Bruneau, BN Davis, BR Cullen, BS Budde, BS Pan, BV Latinkic, C Gove, C Huang, C Rutland, C Wang, CR Bagshaw, CS Rutland, CT Basson, D Franco, D Franco, D Hailstones, D Jin, D Linde van der, D Maughan, D Mornet, D Rhee, D Yelon, DJ Timson, DM Alvarado, DO Fürst, E Berdougo, E Carniel, E Eisenberg, E Flashman, E Rooij van, E Rooij van, EM Small, EP Kirk, F Charron, G Bonne, GE Lyons, H Huxley, H Niimura, H Pannu, H Suzuki, H Wada, HJ Auman, HJ Li, HL Sweeney, HM Warrick, I Morano, I Morano, I Rayment, J Chen, J Fewell, J Flavigny, J Gulick, J Stull, JD Molkentin, Jennifer England, JGF Cleland, JJ Schott, JM Miano, JP Sluijter, JS Davis, JS Park, JT Granados-Riveron, JY Chan, K Imanaka-Yoshida, K Poetter, K Takeda, K Trybus, KD Wilson, KK Turnacioglu, KM Price, KN Ivey, KT Tokuyasu, L Khait, L Zhu, L Zhu, LD Sacks, LM Auckland, M Arad, M Chandra, M Goujon, M Maitra, M Morano, M Xin, MA Geeves, MA Larkin, MC Schaub, MG Posch, MJ Macera, ML Bell, MS Parmacek, N Liu, ND Epstein, ND Moncrief, O Ogut, O Ritter, P Andersen, P Richard, P VanBuren, P Vibert, PFM Ven Van Der, PJ Barton, PJ Barton, PJ Reiser, PS Andersen, Q Shi, QY Li, R Nishigaki, R Walsh, RE Cheney, RE Hershberger, RJ Garriock, RL Moss, RM Toydemir, S Ghatpande, S Goswami, S Lu, S Machida, S Somi, Siobhan Loughna, SJ Smith, SS Lehrer, SW Kubalak, T Boettger, T Takaya, TE Callis, TM Olson, TQP Uyeda, TX O’Brien, V Garg, VJ Ferrans, W Barillot, W Dillmann, W Lehman, W Lu, W Rottbauer, W-H Lee, WF Harrington, WF Harrington, WK Jones, WL Fodor, X Ma, X Ma, Y Hiroi, Y Ishikawa, Y Nakajima, Y Taneda, Y Yang, YH Ching, Z Chen, Z Wang, ZT Kabaeva, ZZ Bao   +163 more
core   +3 more sources

Creating Cell‐Based Hybrid Noodles for Sustainable and Nutrient‐Balanced Diets via a Serum‐Free and Animal‐Free 3D Co‐Differentiation System

Advanced Science, EarlyView.
This study develops a 3D co‐culture and co‐differentiation system for porcine muscle stem cells (pMuSCs) and mesenchymal stem cells (pMSCs) on edible starch‐based scaffolds. The system simultaneously generates myotubes and adipocytes without using serum or chemical inducers.
Xin Guan, Luyi Wang, Wanqiang Sun, Yiwei Feng, Dandan Wang, Haohao Tang, Zhenwu Ma, Guocheng Du, Jian Chen, Jingwen Zhou   +9 more
wiley   +1 more source

TRIM40 Drives Pathological Cardiac Hypertrophy and Heart Failure via Ubiquitination of PKN2

Advanced Science, EarlyView.
This study identifies the E3 ligase TRIM40 as a key driver of pathological cardiac hypertrophy. TRIM40 binds PKN2 via its B‐box domain and, through its C29‐dependent catalytic activity, mediates K63‐linked ubiquitination of PKN2. This modification enhances PKN2 phosphorylation at Ser815, thereby driving hypertrophy.
Risheng Zhao, Xiaoli Cui, Huizhu Du, Zhuoqun Wang, Chang Liu, Linxin Zhang, Jianing Qi, Di Yang, Hui Yu, Shuang Yan, Wei Liu, Haiming Sun, Mengyang Wang   +12 more
wiley   +1 more source

Co‐Opting MBNL‐Dependent Alternative Splicing Cassette Exons to Control Gene Therapy in Myotonic Dystrophy

Annals of Neurology, EarlyView.
Objective Myotonic dystrophy type 1 (DM1) is a highly variable, multisystemic genetic disorder caused by a CTG repeat expansion in the 3′ untranslated region of DMPK. Toxicity is exerted by repeat‐containing DMPK transcripts that sequester muscleblind‐like (MBNL) proteins and lead to deleterious yet predictable changes in alternative splicing.
Samuel T. Carrell, Ellie M. Carrell, Ryan Giovenco, Beverly L. Davidson   +3 more
wiley   +1 more source

Analysis of tarantula skeletal muscle protein sequences and identification of transcriptional isoforms

BMC Genomics, 2009
Background Tarantula has been used as a model system for studying skeletal muscle structure and function, yet data on the genes expressed in tarantula muscle are lacking. Results We constructed a cDNA library from Aphonopelma sp.
Yu Jun, Zhao Fa-Qing, Sun Yongqiao, Zhu Jingui, Craig Roger, Hu Songnian   +5 more
doaj   +1 more source

MyHCs developmental expression patterns and its effect on muscle fibre characteristics in pig

Journal of Applied Animal Research, 2020
This study comprehensively explored muscle fibre characteristics and expression patterns of myosin heavy chain (MyHC) family in skeletal muscles of Large White and Mashen pigs exhibiting differences in muscle fibre development in postnatal muscle growth.
Xiaohong Guo, Yiqi Wu, Yuanyuan Wang, Jingmin Jia, Meng Li, Wei Hei, Zhiqiang He, Yan Zhao, Chunbo Cai, Pengfei Gao, Bugao Li, Guoqing Cao   +11 more
doaj   +1 more source

Changes in rat myocardium contractility under subchronic intoxication with lead and cadmium salts administered alone or in combination

Toxicology Reports, 2020
Subchronic intoxications induced in male rats by repeated intraperitoneal injections of lead acetate and cadmium chloride, administered either alone or in combination, are shown to affect the biochemical, cytological and morphometric parameters of blood,
Yuri L. Protsenko, Svetlana V. Klinova, Oksana P. Gerzen, Larisa I. Privalova, Ilzira A. Minigalieva, Alexander A. Balakin, Oleg N. Lookin, Ruslan V. Lisin, Ksenya A. Butova, Salavat R. Nabiev, Leonid B. Katsnelson, Larisa V. Nikitina, Boris A. Katsnelson   +12 more
doaj   +1 more source