Results 161 to 170 of about 32,263 (310)

The relationship between the cannabinoids and cardiac remodelling: A comprehensive review of pivotal mechanisms and emerging evidence

British Journal of Pharmacology, EarlyView.
Cardiac remodelling and fibrosis after myocardial infarction or during chronic diseases, such as arterial and pulmonary hypertension or diabetes mellitus, continue to be the more important prognostic factors in determining survival, and so the search for effective anti‐fibrotic interventions is an important target for research and therapy in cardiology.
Anna Krzyżewska, Marta Baranowska‐Kuczko, Hanna Kozłowska   +2 more
wiley   +1 more source

Biallelic MYH3 Variants Cause Distal Arthrogryposis in Compound Heterozygosity and a Subclinical Phenotype in Simple Heterozygosity. Codominance or Recessive Inheritance?

Clinical Genetics, EarlyView.
A nuclear family affected by distal arthrogryposis with novel biallelic MYH3 variants, which at the heterozygous state yield a subclinical phenotype, highlighting the complexity of MYH3‐related disorders and their inheritance modes. ABSTRACT Distal arthrogryposis constitutes a highly heterogeneous group of disorders with a critical need for clear ...
Omar Zgheib, Thomas Rio‐Frio, Michel Guipponi, Thierry Nouspikel, Siv Fokstuen, Marc Abramowicz, Philippe Khau Van Kien   +6 more
wiley   +1 more source

LCN2‐ACOD1 Signalling Affects the Post‐Injury Regeneration of Skeletal Muscle Through Mediating Ferroptosis

Cell Proliferation, EarlyView.
LCN2 mediates the suppression of C2C12 myoblast proliferation and myotube formation via erastin‐induced ferroptosis. Mechanistically, the LCN2‐ACOD1 axis regulates skeletal muscle growth via mitochondria‐associated ferroptosis, providing a theoretical basis for the prevention and therapy of muscle‐related diseases.
Xiaojing Hao, Hongwei Shi, Di Wu, Rui Liang, Tong Zhao, Wen Sun, Yue Wang, Xiuju Yu, Xiaomao Luo, Yi Yan, Jiayin Lu, Haidong Wang, Juan Wang   +12 more
wiley   +1 more source

Differential regulation of myosin heavy chains defines new muscle domains in zebrafish. [PDF]

Mol Biol Cell, 2014
Nord H, Burguiere AC, Muck J, Nord C, Ahlgren U, von Hofsten J.   +5 more
europepmc   +1 more source

Resilient Biophysical Phenotype of Memory CD4+ T Cells in Long‐Lived Mice

Immunology, EarlyView.
Aging is associated with increased stiffness and reduced migratory capacity of memory CD4+ T cells; however, these biophysical declines do not persist in exceptionally long‐lived mice. Instead, long‐lived individuals preserve T cell mechanics, migration and intracellular architecture, supporting mechanical resilience as a hallmark of successful immune ...
Aldo Abarca‐Ortega, Blanca González‐Bermúdez, Judith Félix‐Escalera, Mónica González‐Sánchez, Enzo Brito, Mónica De la Fuente, Gustavo R. Plaza   +6 more
wiley   +1 more source

Multi‐Omic Analysis of Scylla serrata Reveals the Allergen Landscape of Mud Crabs and Decapoda Species

Allergy, EarlyView.
Kelvin Fu‐Kiu Ao, Judy Kin Wing Ng, Cherie Tsz‐Yiu Law, Weixue Mu, Shanshan Li, Christine Yee Yan Wai, Man Fung Tang, Shannon Wing Ngor Au, Xiaoyu Liu, Ting Fan Leung, Qing Xiong, Stephen Kwok‐Wing Tsui   +11 more
wiley   +1 more source

Review of expansion microscopy combined with advanced imaging modalities

Journal of Microscopy, EarlyView.
Abstract Expansion microscopy (ExM) is a powerful high‐resolution imaging technique that enhances the spatial resolution of conventional light microscopy by physically enlarging biological specimens by embedding and cross‐linking them in a swellable polymer network.
Natalie Woo, Claire M. Brown
wiley   +1 more source

Transcriptomic Remodeling of Pulmonary Vein Sleeves Suggests a Role in Atrial Arrhythmogenesis in Thoroughbred Horses

Annals of the New York Academy of Sciences, EarlyView.
Myocardial sleeves of the pulmonary veins in racehorses with paroxysmal atrial fibrillation exhibit upregulated pathways associated with tissue structure remodeling. Pathways related to the extracellular matrix and cellular components differ significantly from those in healthy horses.
Magdalena Arevalo‐Turrubiarte, Charlotte E. Edling, Carla Moller‐Levet, Bronte Forbes, Victoria Kemp, Joe Weir, Celia Marr, Rebecca Lewis, Kamalan Jeevaratnam   +8 more
wiley   +1 more source

Myosin heavy chain 9 (MYH9); myosin light chain kinase (MYLK; MLCK) [PDF]

Science-Business eXchange, 2010
openaire   +1 more source

Isometric training at longer muscle–tendon complex lengths: A potential countermeasure to impaired neuro‐muscle–tendon function during space travel

Experimental Physiology, EarlyView.
Abstract Manned space exploration to distant destinations, including Mars, continues to be an aspiration of humankind. Space travel does, however, present many challenges to the body, amongst which adaptation to microgravity is perhaps the largest. For instance, both short and long manned spaceflight missions have shown substantial deleterious effects ...
Gerard McMahon, Andy Sanderson, Hans Degens   +2 more
wiley   +1 more source