Results 191 to 200 of about 32,263 (310)

The mitochondrial‐targeted antioxidant SkQ1 prevents skeletal muscle mitochondrial‐apoptotic but not necroptotic signalling during ovarian cancer

The Journal of Physiology, EarlyView.
Abstract figure legend An evaluation of the degree to which mitochondrial hydrogen peroxide emission (mH2O2)‐mediated apoptotic and necroptotic signalling contributes to skeletal muscle atrophy in an orthotopic epithelial ovarian cancer (EOC) model. To determine whether attenuating mH2O2 could prevent regulated cell death signalling and mitigate muscle
Shahrzad Khajehzadehshoushtar, Luca J. Delfinis, Fasih A. Rahman, Madison C. Garibotti, Shivam Gandhi, Aditya N. Brahmbhatt, Brooke A. Morris, Bianca Garlisi, Sylvia Lauks, Caroline Aitken, Leslie Ogilvie, Zhu‐Xu Zhang, Jeremy A. Simpson, Joe Quadrilatero, Jim Petrik, Christopher G. R. Perry   +15 more
wiley   +1 more source

SCarP: Proteome Heterogeneity Characterization of Primary Mouse Cardiomyocytes. [PDF]

Circ Res
Chazarin B, Binek A, Janssens JV, Becker LE, Kreimer S, Haghani A, Cantlon J, Pham J, Hutton A, Meyer JG, Krieger JR, Zirem Y, Karlstaedt A, Van Eyk JE.   +13 more
europepmc   +1 more source

The link between sarcopenic obesity and Alzheimer's disease: a brain‐derived neurotrophic factor point of view

The Journal of Physiology, EarlyView.
Abstract figure legend A, Sarcopenic obesity is defined as the age‐related loss of skeletal muscle mass and function that often leads to the progression of comorbidities, such as Alzheimer's disease (AD). Though the exact link between the two diseases is unknown, alterations in brain‐derived neurotrophic factor (BDNF) may be a contributor.
Emily N. Copeland, Paul J. LeBlanc, Paula Duarte‐Guterman, Val A. Fajardo, Rebecca E. K. MacPherson   +4 more
wiley   +1 more source

Structure of the human nonmuscle myosin 2A motor domain: Insights into isoform-specific mechanochemistry. [PDF]

J Biol Chem
Heiringhoff RS, Greve JN, Zahn M, Manstein DJ.   +3 more
europepmc   +1 more source

Carbonylation of myosin heavy chains in rat heart during diabetes. [PDF]

Biochem Pharmacol, 2010
Shao CH, Rozanski GJ, Nagai R, Stockdale FE, Patel KP, Wang M, Singh J, Mayhan WG, Bidasee KR.   +8 more
europepmc   +1 more source

Utility of local capillary supply indices: Insights from computational image‐based modelling

The Journal of Physiology, EarlyView.
Abstract figure legend Local capillary distribution and fibre geometry influence oxygen availability in skeletal muscle. Image‐based modelling of tissue PO2${{P}_{{{{\mathrm{O}}}_2}}}$ shows that area‐based measures of capillary supply – the local capillary density (LCDi) and local maximum diffusion distance (Dmax,i) – most accurately represent the ...
Abdullah A. Al‐Shammari, Roger W. P. Kissane, Ali Ashkanani, Ashraf Al Madhoun, Fahd Al‐Mulla, Eamonn A. Gaffney, Stuart Egginton   +6 more
wiley   +1 more source

Paradigm shifts: how electrical stimulation opened up new avenues in science and medicine. [PDF]

Eur J Transl Myol
Salmons S.
europepmc   +1 more source

Antioxidant supplementation blunts the proteome response to 3 weeks of sprint interval training preferentially in human type 2 muscle fibres

The Journal of Physiology, EarlyView.
Abstract figure legend Sprint interval training (SIT) is a popular time‐efficient type of endurance training. Healthy young men performed nine SIT sessions (4–6 × 30 s all‐out cycling sprints) over 3 weeks while being supplemented with antioxidants (high doses of vitamins C and E) or placebo. Muscle biopsies taken before and after the first SIT session
Victoria L. Wyckelsma, Marta Murgia, Sigitas Kamandulis, Stefano Gastaldello, Marius Brazaitis, Audrius Snieckus, Nerijus Eimantas, Mati Pääsuke, Sebastian Edman, William Apro, Daniel C. Andersson, Håkan Westerblad, Tomas Venckunas   +12 more
wiley   +1 more source

Eppur si muove: the dynamic brain pericyte. [PDF]

Fluids Barriers CNS
Wilhelm I, Győri F, Dudás T, Nagy V, Shreeya T, Krecsmarik M, Farkas AE, Fazakas C, Krizbai IA.   +8 more
europepmc   +1 more source

Differential expression of caveolins and myosin heavy chains in response to forced exercise in rats. [PDF]

Lab Anim Res, 2012
Park S, Hong Y, Lee Y, Won J, Chang KT, Hong Y.   +5 more
europepmc   +1 more source