Results 71 to 80 of about 32,263 (310)

PLASTICITY OF SKELETAL MUSCLE STUDIED BY STEREOLOGY

Image Analysis and Stereology, 2011
The present contribution provides an overview of stereological methods applied in the skeletal muscle research at the Institute of Anatomy of the Medical Faculty in Ljubljana. Interested in skeletal muscle plasticity we studied three different topics: (i)
Ida Eržen
doaj   +1 more source

MYH2 myopathy, a new case expands the clinical and pathological spectrum of the recessive form

Molecular Genetics & Genomic Medicine, 2020
Background Hereditary myosin myopathies are a group of rare muscle disorders, caused by mutations in genes encoding for skeletal myosin heavy chains (MyHCs). MyHCIIa is encoded by MYH2 and is expressed in fast type 2A and 2B muscle fibers. MYH2 mutations
Roberta Telese, Serena Pagliarani, Alberto Lerario, Patrizia Ciscato, Gigliola Fagiolari, Denise Cassandrini, Nadia Grimoldi, Giorgio Conte, Claudia Cinnante, Filippo M. Santorelli, Giacomo P. Comi, Monica Sciacco, Lorenzo Peverelli   +12 more
doaj   +1 more source

Increased Blood Flow and Tendon Swelling Precedes Vascular Expansion and Tissue Matrix Changes In Early Human Tendinopathy: A Potential Window for Superior Treatment Response

Advanced Science, EarlyView.
Human participants with early‐ or chronic‐stage tendinopathy and healthy controls are investigated using ultrasound Doppler, 3T and 7T MRI, and tendon biopsies. Tendon swelling and hyperperfusion are evident early, while vascular growth and extracellular matrix changes are most pronounced in chronic tendinopathy. Early intervention may provide superior
Max F. R. Merkel, Nikolaj M. Malmgaard‐Clausen, Marius Lendal, Hartwig R. Siebner, René B. Svensson, Stephanie G. Dakin, Marcus Krüger, Luisa Schmidt, Jakob Agergaard, Ching‐Yan Chloé Yeung, S. Peter Magnusson, Michael Kjaer   +11 more
wiley   +1 more source

Myosin Heavy Chain Isoforms in Human Extraocular Muscles

Investigative Opthalmology & Visual Science, 2003
To investigate the myosin heavy chain (MyHC) composition of human extraocular (EOM) and levator palpebrae (LP) muscle fibers.Adult human EOMs and LP were studied with SDS-PAGE, immunoblots, and immunocytochemistry, with antibodies against six MyHC isoforms.
Daniel, Kjellgren, Lars-Eric, Thornell, Jesper, Andersen, Fatima, Pedrosa-Domellöf   +3 more
openaire   +2 more sources

Myosin isoenzymes in human hypertrophic hearts. Shift in atrial myosin heavy chains and in ventricular myosin light chains [PDF]

European Heart Journal, 1984
The myosin light chain complement and proteolytic peptide patterns of myosin heavy chains were studied by two-dimensional and one-dimensional electrophoretic techniques respectively, in a total of 57 samples from ventricular and atrial tissues of normal and hypertrophied human hearts.
Schaub, M C, Tuchschmid, C R, Srihari, T, Hirzel, H O   +3 more
openaire   +2 more sources

Catalyst‐Free Collagen Filament Crosslinking for Engineering Anisotropic and Mechanically Robust Tissue Scaffolds

Advanced Science, EarlyView.
A bioorthogonal rhodamine/PEG crosslinking strategy is introduced to engineer dense collagen hydrogels with high mechanical resilience and cytocompatibility. Integration with wet‐spinning enables the fabrication of uniaxially aligned, cell‐laden collagen filaments that activate mechanotransductive signaling and support functional muscle regeneration in
JuYeon Kim, Hanjun Hwangbo, ByungJoon Choi, Dogeon Yoon, GeunHyung Kim   +4 more
wiley   +1 more source

Functional defects in hiPSCs-derived cardiomyocytes from patients with a PLEKHM2-mutation associated with dilated cardiomyopathy and left ventricular non-compaction

Biological Research, 2023
Dilated cardiomyopathy (DCM) is a primary myocardial disease, leading to heart failure and excessive risk of sudden cardiac death with rather poorly understood pathophysiology.
Nataly Korover, Sharon Etzion, Alexander Cherniak, Tatiana Rabinski, Aviva Levitas, Yoram Etzion, Rivka Ofir, Ruti Parvari, Smadar Cohen   +8 more
doaj   +1 more source

Preferential Myosin Heavy Chain Isoform B Expression May Contribute to the Faster Velocity of Contraction in Veins versus Arteries [PDF]

, 2007
Smooth muscle myosin heavy chains occur in 2 isoforms, SMA (slow) and SMB (fast). We hypothesized that the SMB isoform is predominant in the faster-contracting rat vena cava compared to thoracic aorta.
Eddinger, Thomas, Fink, Gregory D, Kayal, Anas, Rondelli, Catherine M, Rovner, Arthur S, Szasz, Irina T, Thakali, Keshari, Watson, Ralph E, Watts, Stephanie W   +8 more
core   +1 more source

Chloroplast Stress Signals Orchestrate Epidermis‐Specific Remodeling of Mitochondria and ER Under High Light

Advanced Science, EarlyView.
High light exposure triggers an epidermis‐specific remodeling of mitochondria and ER in Arabidopsis, driven by chloroplast‐derived signals. Live‐cell imaging shows that HL rapidly suppresses mitochondrial motility, followed by fusion‐driven elongation and ER cisternal expansion.
Evan R. Angelos, Hee‐Seung Choi, Jingzhe Guo, Andrea A. Zanini, Tessa M. Burch‐Smith, Emily Snyder, Matthew Part, Wilhelmina van de Ven, Manhoi Hur, Gerd Ulrich Balcke, Alain Tissier, Quanqing Zhang, Katayoon Dehesh   +12 more
wiley   +1 more source

Regulatory mechanisms of muscle fiber types and their possible interactions with external nutritional stimuli

Journal of Physical Fitness and Sports Medicine, 2012
In this review, we briefly summarize muscle fiber types and mechanisms that regulate their expression from nutritional stimulus. To begin with, we introduce genes and their location on myosin heavy chains (MyHC). Next, we show three major transcriptional
Koichi Nakazato, Arata Tsutaki
doaj   +1 more source