1P139 Structural basis of myosin phosphatase inhibitor, CPI-17
S. Ohki, M. Eto, K. Yokota, F. Matsuzawa
openaire +2 more sources
This study comprehended the allergen profiles of six edible crab species using proteomic and transcriptomic analyses and identified 11 putative allergens. King crab has a distinct protein and allergen profile, with the discovery of malate dehydrogenase as a novel king crab‐specific allergen registered as Para c 11.
Shanshan Li +11 more
wiley +1 more source
Non-muscle myosin II is a promising therapeutic target. [PDF]
Miller CA +2 more
europepmc +1 more source
Cellular Stress, Inflammation and Barrier Damage in Gut Epithelial Cells Caused by Aspartame
This study shows that aspartame, at dietary‐relevant doses, induces cytotoxicity, cellular distress associated with endoplasmic reticulum stress, oxidative stress, DNA replication and repair mechanism disturbance culminating in epithelial barrier damage.
Yagiz Pat +16 more
wiley +1 more source
Emerging Pharmacological and Invasive Therapies for Hypertrophic Cardiomyopathy with Obstructive Physiology. [PDF]
Li-Wen Chu E, Seung Kim D, Masri A.
europepmc +1 more source
Vasoreactivity as a Measure of Kidney Viability During Ex Vivo Normothermic Machine Perfusion
This study aimed to investigate the influence of warm ischemic injury on renal vascular responsiveness to vasoactive drugs during normothermic machine perfusion (NMP). We found that the vascular responses to dopamine and norepinephrine could be used as objective indicators to assess kidney viability during NMP.
Isa M. van Tricht +4 more
wiley +1 more source
How Actin Polymerization and Myosin II Activity Regulate Focal Adhesion Dynamics in Motile Cells. [PDF]
Kovaleva A +4 more
europepmc +1 more source
Non‐canonical PKG1 regulation in cardiovascular health and disease
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley +1 more source
Current and emerging medical and surgical therapy in hypertrophic cardiomyopathy. [PDF]
Kim KA, Jung MH.
europepmc +1 more source
Ether-a-go-go related gene-1a potassium channel abundance varies within specific skeletal muscle fiber type [PDF]
Anderson, Luke B. +5 more
core +1 more source

