Results 201 to 210 of about 94,421 (295)

1P139 Structural basis of myosin phosphatase inhibitor, CPI-17

open access: yesSeibutsu Butsuri, 2004
S. Ohki, M. Eto, K. Yokota, F. Matsuzawa
openaire   +2 more sources

Revealing the Diverse Allergenic Protein Repertoire of Six Widely Consumed Crab Species: A Species‐Specific Allergen in King Crab

open access: yesAllergy, EarlyView.
This study comprehended the allergen profiles of six edible crab species using proteomic and transcriptomic analyses and identified 11 putative allergens. King crab has a distinct protein and allergen profile, with the discovery of malate dehydrogenase as a novel king crab‐specific allergen registered as Para c 11.
Shanshan Li   +11 more
wiley   +1 more source

Non-muscle myosin II is a promising therapeutic target. [PDF]

open access: yesTrends Pharmacol Sci
Miller CA   +2 more
europepmc   +1 more source

Cellular Stress, Inflammation and Barrier Damage in Gut Epithelial Cells Caused by Aspartame

open access: yesAllergy, EarlyView.
This study shows that aspartame, at dietary‐relevant doses, induces cytotoxicity, cellular distress associated with endoplasmic reticulum stress, oxidative stress, DNA replication and repair mechanism disturbance culminating in epithelial barrier damage.
Yagiz Pat   +16 more
wiley   +1 more source

Vasoreactivity as a Measure of Kidney Viability During Ex Vivo Normothermic Machine Perfusion

open access: yesArtificial Organs, EarlyView.
This study aimed to investigate the influence of warm ischemic injury on renal vascular responsiveness to vasoactive drugs during normothermic machine perfusion (NMP). We found that the vascular responses to dopamine and norepinephrine could be used as objective indicators to assess kidney viability during NMP.
Isa M. van Tricht   +4 more
wiley   +1 more source

Non‐canonical PKG1 regulation in cardiovascular health and disease

open access: yesBritish Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

Ether-a-go-go related gene-1a potassium channel abundance varies within specific skeletal muscle fiber type [PDF]

open access: yes, 2019
Anderson, Luke B.   +5 more
core   +1 more source

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