Results 261 to 270 of about 61,568 (292)
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Nature Reviews Rheumatology, 2018
The idiopathic inflammatory myopathies (IIMs; also known as myositis) are a heterogeneous group of disorders in which a common feature is chronic inflammation of skeletal muscle, leading to muscle weakness. Other organs are frequently affected in IIMs, such as the skin, joints, lungs, gastrointestinal tract and heart, contributing to morbidity and ...
I. Lundberg, M. Visser, V. Werth
semanticscholar +4 more sources
The idiopathic inflammatory myopathies (IIMs; also known as myositis) are a heterogeneous group of disorders in which a common feature is chronic inflammation of skeletal muscle, leading to muscle weakness. Other organs are frequently affected in IIMs, such as the skin, joints, lungs, gastrointestinal tract and heart, contributing to morbidity and ...
I. Lundberg, M. Visser, V. Werth
semanticscholar +4 more sources
Annals of the Rheumatic Diseases, 2021
Objectives To investigate whether autoimmunity to transcriptional intermediary factor 1 (TIF1)γ, a ubiquitous nuclear autoantigen for myositis-specific autoantibodies detected in patients with dermatomyositis (DM) is pathogenetic for inflammatory ...
N. Okiyama +13 more
semanticscholar +1 more source
Objectives To investigate whether autoimmunity to transcriptional intermediary factor 1 (TIF1)γ, a ubiquitous nuclear autoantigen for myositis-specific autoantibodies detected in patients with dermatomyositis (DM) is pathogenetic for inflammatory ...
N. Okiyama +13 more
semanticscholar +1 more source
Immune checkpoint inhibitor-related myositis and myocarditis in patients with cancer
Neurology, 2018Objective To report the clinicopathologic features and outcome of myositis in patients treated with immune checkpoint inhibitors (ICIs) (irMyositis).
Mehdi Touat +19 more
semanticscholar +1 more source
Nature Reviews Rheumatology, 2018
As with the treatment of many immune-mediated diseases, managing myositis encompasses diverse factors, which present a challenge to the physician caring for these patients. The idiopathic inflammatory myopathies (IIMs, also known as myositis), are fundamentally heterogeneous; many contributory immunological perturbations are involved in the ...
C. Oddis, R. Aggarwal
semanticscholar +4 more sources
As with the treatment of many immune-mediated diseases, managing myositis encompasses diverse factors, which present a challenge to the physician caring for these patients. The idiopathic inflammatory myopathies (IIMs, also known as myositis), are fundamentally heterogeneous; many contributory immunological perturbations are involved in the ...
C. Oddis, R. Aggarwal
semanticscholar +4 more sources
Inflammatory Myositis in Cancer Patients Receiving Immune Checkpoint Inhibitors
Arthritis & Rheumatology, 2020To estimate the incidence of immune checkpoint inhibitor–related myositis (ICI‐myositis) in cancer patients receiving ICIs, and to report associated clinical manifestations, patterns of care, and outcomes.
J. Aldrich +8 more
semanticscholar +1 more source
Pathological autoantibody internalisation in myositis
Annals of the Rheumatic DiseasesObjectives Autoantibodies targeting intracellular proteins are common in various autoimmune diseases. In the context of myositis, the pathologic significance of these autoantibodies has been questioned due to the assumption that autoantibodies cannot ...
Iago Pinal-Fernández +30 more
semanticscholar +1 more source
Current Opinion in Rheumatology, 1984
Dermatomyositis appears to be associated with a greater frequency of malignancy than expected in the general population. For polymyositis, there does not appear to be a greatly increased risk of malignancy. Ovarian cancer may be overrepresented in women with dermatomyositis and difficult to detect.
openaire +5 more sources
Dermatomyositis appears to be associated with a greater frequency of malignancy than expected in the general population. For polymyositis, there does not appear to be a greatly increased risk of malignancy. Ovarian cancer may be overrepresented in women with dermatomyositis and difficult to detect.
openaire +5 more sources
Current Allergy and Asthma Reports, 2012
Ocular myositis frequently manifests with orbital pain and diplopia. The diagnosis of ocular myositis falls within the overall classification of idiopathic orbital inflammatory diseases, defined as non-infective non-specific orbital inflammation without identifiable local or systemic causes.
Avinash Gurbaxani +3 more
openaire +3 more sources
Ocular myositis frequently manifests with orbital pain and diplopia. The diagnosis of ocular myositis falls within the overall classification of idiopathic orbital inflammatory diseases, defined as non-infective non-specific orbital inflammation without identifiable local or systemic causes.
Avinash Gurbaxani +3 more
openaire +3 more sources
Current Opinion in Rheumatology, 1991
The mainstay of therapy for polymyositis-dermatomyositis continues to be corticosteroids either alone or in combination with other immunosuppressive agents. Intravenous cyclophosphamide may be beneficial in some patients, and success with cyclosporine has been reported in children with dermatomyositis.
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The mainstay of therapy for polymyositis-dermatomyositis continues to be corticosteroids either alone or in combination with other immunosuppressive agents. Intravenous cyclophosphamide may be beneficial in some patients, and success with cyclosporine has been reported in children with dermatomyositis.
openaire +3 more sources
Rheumatology International, 2016
We aimed to study the prevalence and clinical associations of myositis-specific autoantibodies (MSAs) and myositis-associated autoantibodies (MAAs) in a large cohort of Indian patients with idiopathic inflammatory myositis (IIM). Clinical details and serum samples were collected from patients with IIM (satisfying Bohan and Peter Criteria, 1975) and CTD-
Sanjay Dwivedi +2 more
openaire +3 more sources
We aimed to study the prevalence and clinical associations of myositis-specific autoantibodies (MSAs) and myositis-associated autoantibodies (MAAs) in a large cohort of Indian patients with idiopathic inflammatory myositis (IIM). Clinical details and serum samples were collected from patients with IIM (satisfying Bohan and Peter Criteria, 1975) and CTD-
Sanjay Dwivedi +2 more
openaire +3 more sources