Pediatric immune-mediated necrotizing myopathy [PDF]
Frontiers in Neurology, 2023 Immune-mediated necrotizing myopathy (IMNM) is a type of inflammatory myopathy. Most patients with IMNM produce anti-3-hydroxy-3-methylglutaryl coenzyme A reductase or anti-signal-recognition particle autoantibodies.
Chen-Hua Wang +4 more
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Characteristics of cardiac involvement in immune-mediated necrotizing myopathy [PDF]
Frontiers in Immunology, 2023 ObjectiveTo investigate the characteristics of cardiac involvement due to Immune-mediated Necrotizing Myopathy (IMNM).MethodsPatients diagnosed with Immune-mediated Necrotizing Myopathy (IMNM) who attended the Department of Neurology and the Department ...
Mengyang Liu +5 more
doaj +4 more sources
Immune-Mediated Necrotizing Myopathy (IMNM): A Story of Antibodies [PDF]
AntibodiesImmune-mediated necrotizing myopathy (IMNM) is a rare and severe disease that corresponds to a specific entity of idiopathic inflammatory myopathy. Patients with IMNM suffer from proximal muscle weakness, and present high levels of creatine kinase and ...
Sarah Julien +5 more
doaj +3 more sources
Clinical-pathologic classification of anti-HMGCR-positive immune-mediated necrotizing myopathy [PDF]
Scientific ReportsAnti-HMGCR-positive immune-mediated necrotizing myopathy (IMNM), also anti-HMGCR myopathy, was initially considered as an exclusively skeletal muscular disease, observed in elderly patients with an acute onset.
Yuyan Cao +14 more
doaj +3 more sources
MRI patterns of thigh muscle involvement in immune-mediated necrotizing myopathy and dermatomyositis [PDF]
BMC RheumatologyBackground Immune-mediated necrotizing myopathy (IMNM) and dermatomyositis (DM) are characterized by weakness, hyperCKemia, associated autoantibodies, and varying extramuscular manifestations.
Anson W. Wilks +5 more
doaj +3 more sources
Beyond the Generalized Weakness: A Rare Case of Statin-Induced Immune-Mediated Necrotizing Myopathy [PDF]
Journal of Investigative Medicine High Impact Case ReportsStatin-induced immune-mediated necrotizing myopathy (IMNM) is a rare subtype of idiopathic inflammatory myopathy associated with statin exposure and characterized by positive anti-hydroxymethylglutaryl coenzyme A reductase antibodies. Here, we describe a
Leo Sakai DO +2 more
doaj +3 more sources
SAGE Open Medical Case Reports, 2020 Anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) immune-mediated necrotizing myopathy is a subtype of idiopathic inflammatory myopathy which may be associated with statin exposure.
Darosa Lim +6 more
doaj +2 more sources
Therapeutic Effect Comparisons of Cyclophosphamide and Methotrexate in Immune-Mediated Necrotizing Myopathy [PDF]
International Journal of General MedicineQiang Li,1,* Jun Zhou,2,* Wenhan Huang,2 Lin Tang2 1Department of Rheumatology and Immunology, The First People’s Hospital of Yibin, Yibin, Sichuan, People’s Republic of China; 2Department of Rheumatology and Immunology, The Second ...
Li Q, Zhou J, Huang W, Tang L
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Treatment of refractory immune-mediated necrotizing myopathy with efgartigimod [PDF]
Frontiers in ImmunologyObjectiveWe aimed to explore the efficacy and safety of efgartigimod in patients with refractory immune-mediated necrotizing myopathy (IMNM).MethodsThis open-label pilot observational study included seven patients with refractory IMNM, all of whom ...
MengTing Yang +11 more
doaj +2 more sources
Tuberculosis-Induced Immune-Mediated Necrotizing Myopathy: A Challenging Case Scenario in a Non-Endemic Country [PDF]
ReportsBackground and Clinical Significance: Tuberculosis (TB) poses a significant global health challenge; although low–middle income countries carry the heaviest burden, its diagnosis and treatment can be challenging in any country.
Agnese Colpani +5 more
doaj +2 more sources