Results 11 to 20 of about 3,889 (160)
Pediatric immune-mediated necrotizing myopathy [PDF]
Frontiers in Neurology, 2023 Immune-mediated necrotizing myopathy (IMNM) is a type of inflammatory myopathy. Most patients with IMNM produce anti-3-hydroxy-3-methylglutaryl coenzyme A reductase or anti-signal-recognition particle autoantibodies. IMNM is much rarer in children than in adults.
Wen-Chen Liang
exaly +7 more sources
Immune-Mediated Necrotizing Myopathy (IMNM): A Story of Antibodies [PDF]
AntibodiesImmune-mediated necrotizing myopathy (IMNM) is a rare and severe disease that corresponds to a specific entity of idiopathic inflammatory myopathy. Patients with IMNM suffer from proximal muscle weakness, and present high levels of creatine kinase and necrotic myofibers.
Fabienne Jouen +2 more
exaly +6 more sources
Characteristics of cardiac involvement in immune-mediated necrotizing myopathy [PDF]
Frontiers in Immunology, 2023 ObjectiveTo investigate the characteristics of cardiac involvement due to Immune-mediated Necrotizing Myopathy (IMNM).MethodsPatients diagnosed with Immune-mediated Necrotizing Myopathy (IMNM) who attended the Department of Neurology and the Department of Rheumatology and Immunology at the First Medical Center of the PLA General Hospital between ...
Qiang Shi
exaly +5 more sources
Immune Mediated Necrotizing Myopathy: A Rare Complication of Statin Therapy [PDF]
Clinics and Practice, 2020 Immune mediated necrotizing myopathy (IMNM) is part of the inflammatory myopathies group of diseases and presents with muscle weakness, myalgias and elevated serum creatine phosphokinase (CPK). Statin-induced IMNM is a rare complication. We present a patient with IMNM secondary to simvastatin use. The patient presented with proximal myopathy, dysphagia,
Shady Piedra Abusharar +2 more
exaly +4 more sources
Treatment of refractory immune-mediated necrotizing myopathy with efgartigimod [PDF]
Frontiers in ImmunologyObjectiveWe aimed to explore the efficacy and safety of efgartigimod in patients with refractory immune-mediated necrotizing myopathy (IMNM).MethodsThis open-label pilot observational study included seven patients with refractory IMNM, all of whom received intravenous efgartigimod treatment.
Mengting Yang +2 more
exaly +5 more sources
Treatment of Immune-Mediated Necrotizing Myopathy [PDF]
Current Treatment Options in Rheumatology, 2023 Immune-mediated necrotizing myositis (IMNM) is a rare autoimmune disorder characterized by proximal muscle weakness, elevated creatine kinase levels, and necrosis of muscle fibers. While the exact pathogenesis of IMNM remains unknown, anti-HMGCR and anti-SRP autoantibodies are associated with different predisposing factors, clinical manifestations, and
Sandra Amara Ogbonnaya-Whittlesey +4 more
openaire +4 more sources
Statins and Immune-Mediated Necrotizing Myopathy
Clinical Management Issues, 2019 Statins are a well-recognized cause of a variety of skeletal myopathic effects, which generally resolve when discontinuing the treatment. Among autoimmune manifestations associated with statins, there is immune-mediated necrotizing myopathy (IMNM).The present article summarizes the main features of statin-related IMNM, describing diagnosis ...
Turrin, Mauro, Mauro Turrin
openaire +5 more sources
Statin-Induced Immune-Mediated Necrotizing Myopathy: A Case Report of a Rare and Underrecognized Cause of Progressive Weakness. [PDF]
CureusStatin-induced necrotizing autoimmune myopathy is a rare immune-mediated process that leads to muscle necrosis and occurs following exposure to statin therapy. The diagnostic clue for this disorder stems from the development of a proximal muscle weakness
Tangutoori S +4 more
europepmc +2 more sources
Clinical-pathologic classification of anti-HMGCR-positive immune-mediated necrotizing myopathy. [PDF]
Sci RepAnti-HMGCR-positive immune-mediated necrotizing myopathy (IMNM), also anti-HMGCR myopathy, was initially considered as an exclusively skeletal muscular disease, observed in elderly patients with an acute onset.
Cao Y +14 more
europepmc +2 more sources
Immune-mediated necrotizing myopathy: Report of two cases [PDF]
World Journal of Clinical Cases, 2023 Immune-mediated necrotizing myopathy is a rare autoimmune myopathy characterized by muscle weakness and elevated serum creatine kinase, with unique skeletal muscle pathology and magnetic resonance imaging features.In this paper, two patients are reported: One was positive for anti-signal recognition particle antibody, and the other was positive for ...
Chen, Bi-Hong +3 more
openaire +3 more sources