Results 11 to 20 of about 5,602 (207)

Statin-associated anti-HMGCR immune-mediated necrotizing myopathy with dermatomyositis-like features: A case report

SAGE Open Medical Case Reports, 2020
Anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) immune-mediated necrotizing myopathy is a subtype of idiopathic inflammatory myopathy which may be associated with statin exposure.
Darosa Lim, Océane Landon-Cardinal, Benjamin Ellezam, Annie Belisle, Annie Genois, Jennifer Sirois, Josiane Bourré-Tessier   +6 more
doaj   +2 more sources

Beyond the Generalized Weakness: A Rare Case of Statin-Induced Immune-Mediated Necrotizing Myopathy [PDF]

Journal of Investigative Medicine High Impact Case Reports
Statin-induced immune-mediated necrotizing myopathy (IMNM) is a rare subtype of idiopathic inflammatory myopathy associated with statin exposure and characterized by positive anti-hydroxymethylglutaryl coenzyme A reductase antibodies. Here, we describe a
Leo Sakai DO, Hana Kazbour MD, James Huang MD   +2 more
doaj   +2 more sources

Immune-Mediated Necrotizing Myopathy Manifesting after Five Years of Statin Therapy [PDF]

Case Reports in Rheumatology, 2023
Immune-mediated necrotizing myopathy (IMNM) is an increasingly common and serious condition in which autoantibodies attack muscle fibers causing clinically significant muscle weakness, fatigue, and myalgias.
Nathan G. DeRon, Francis Fischer, Dylan Lopez, Elizabeth C. Brewer   +3 more
doaj   +2 more sources

Immune-Mediated Necrotizing Myopathy Initially Presenting as Erythema Nodosum

Journal of Inflammation Research, 2020
Shuni Ying, Sheng Li, Shunli Tang, Qingmiao Sun, Deren Fang, Yali Li, Dingxian Zhu, Hong Fang, Jianjun Qiao Department of Dermatology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, People’s Republic of ...
Ying S, Li S, Tang S, Sun Q, Fang D, Li Y, Zhu D, Fang H, Qiao J   +8 more
doaj   +3 more sources

An atorvastatin‐induced positive anti‐HMGCR immune‐mediated necrotizing myopathy case [PDF]

Clinical Case Reports
Key Clinical Message Statins can commonly cause myopathy. Most of the time, stopping the culprit drug should solve the problem. However, if the drug has been discontinued but muscle weakness continues to worsen, immune‐mediated myopathy should be taken ...
Nattanicha Chaisrimaneepan, Jerapas Thongpiya, Pitchaporn Yingchoncharoen, Sakditad Saowapa   +3 more
doaj   +2 more sources

Treatment of Immune-Mediated Necrotizing Myopathy. [PDF]

Curr Treatm Opt Rheumatol, 2023
Ogbonnaya-Whittlesey SA, Kobrin D, Casal-Dominguez M, Mammen AL, Pinal-Fernandez I.   +4 more
europepmc   +3 more sources

Rheumatoid Arthritis Associated With Anti-Signal Recognition Particle Immune-Mediated Necrotizing Myopathy: A Case Report [PDF]

Journal of Investigative Medicine High Impact Case Reports
Immune-mediated necrotizing myopathy (IMNM) is a rare subtype of idiopathic inflammatory myopathy that is characterized by severe subacute proximal weakness, myofiber necrosis, and significantly elevated serum creatine kinase.
Mohamed Reda Belkhribchia MD, Johannes Alexander Lobrinus MD, Lamyaa Semlil MD, Nicolas Chauveau MD, Abdelaziz Ajrinija MD, Kristof Egervari MD, Zine Elabidine Ennhaili MD   +6 more
doaj   +2 more sources

Corrigendum: Characteristics of cardiac involvement in immune-mediated necrotizing myopathy [PDF]

Frontiers in Immunology, 2023
Mengyang Liu, Ying Lin, Lingya Qiao, Lingya Qiao, Juan Chen, Qiang Shi   +5 more
doaj   +2 more sources

Statins and muscle – friends or foes? Discussions based on a case report [PDF]

Romanian Journal of Rheumatology, 2022
Immune-mediated necrotizing myopathy (IMNM) is a type of autoimmune myopathy characterized by relatively severe proximal weakness, myofiber necrosis with minimal inflammatory cell infiltrate on muscle biopsy, and infrequent extra-muscular involvement ...
Andra Patricia Stanciu, Cristina Nita, Laura Groseanu   +2 more
doaj   +1 more source

A tough pill to swallow: Two cases of statin-induced necrotizing autoimmune myopathy manifesting as dysphagia and transaminitis

SAGE Open Medical Case Reports, 2023
Although 3-hydroxy-3-methyl-glutaryl-coenzyme A (HMG-CoA) reductase inhibitors are well tolerated, a small subset of patients may develop autoimmune myopathy, classified as immune-mediated necrotizing myopathy.
Hunza Chaudhry, Joanne Lin, Rameen Atefi, Jeffrey Hagino, Candice Marie Yuvienco, Marina Roytman   +5 more
doaj   +1 more source