Results 21 to 30 of about 2,380,685 (149)

Immune-Mediated Necrotizing Myopathy Manifesting after Five Years of Statin Therapy

Case Reports in Rheumatology, 2023
Immune-mediated necrotizing myopathy (IMNM) is an increasingly common and serious condition in which autoantibodies attack muscle fibers causing clinically significant muscle weakness, fatigue, and myalgias.
Nathan G. DeRon, Francis Fischer, Dylan Lopez, Elizabeth C. Brewer   +3 more
doaj   +2 more sources

Anti-3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Immune-Mediated Necrotizing Myopathy following mRNA SARS-CoV-2 Vaccination

Case Reports in Neurological Medicine, 2023
The new coronavirus (COVID-19) pandemic has resulted in the unprecedented production of vaccines. In this context, the possible adverse effects remain to be identified and reported.
Marta Rodrigues de Carvalho, Myrian Mathildes Sá de Deus Rocha, Vinícius Alves Bezerra, Maciel Eduardo de Pontes, Maria Cristina del Negro, Julio Salgado Antunes, Vinícius Viana Abreu Montanaro, Rubens Nelson Morato Fernandez   +7 more
doaj   +2 more sources

Rheumatoid Arthritis Associated With Anti-Signal Recognition Particle Immune-Mediated Necrotizing Myopathy: A Case Report

Journal of Investigative Medicine High Impact Case Reports
Immune-mediated necrotizing myopathy (IMNM) is a rare subtype of idiopathic inflammatory myopathy that is characterized by severe subacute proximal weakness, myofiber necrosis, and significantly elevated serum creatine kinase.
Mohamed Reda Belkhribchia MD, Johannes Alexander Lobrinus MD, Lamyaa Semlil MD, Nicolas Chauveau MD, Abdelaziz Ajrinija MD, Kristof Egervari MD, Zine Elabidine Ennhaili MD   +6 more
doaj   +2 more sources

An atorvastatin‐induced positive anti‐HMGCR immune‐mediated necrotizing myopathy case [PDF]

Clinical Case Reports
Key Clinical Message Statins can commonly cause myopathy. Most of the time, stopping the culprit drug should solve the problem. However, if the drug has been discontinued but muscle weakness continues to worsen, immune‐mediated myopathy should be taken ...
Nattanicha Chaisrimaneepan, Jerapas Thongpiya, Pitchaporn Yingchoncharoen, Sakditad Saowapa   +3 more
doaj   +2 more sources

Statins and muscle – friends or foes? Discussions based on a case report [PDF]

Romanian Journal of Rheumatology, 2022
Immune-mediated necrotizing myopathy (IMNM) is a type of autoimmune myopathy characterized by relatively severe proximal weakness, myofiber necrosis with minimal inflammatory cell infiltrate on muscle biopsy, and infrequent extra-muscular involvement ...
Andra Patricia Stanciu, Cristina Nita, Laura Groseanu   +2 more
doaj   +1 more source

Anti-SRP Antibodies and Myocarditis in Systemic Sclerosis Overlap Syndrome with Immune-Mediated Necrotizing Myositis (IMNM)

Medicina
Overlap syndrome of systemic sclerosis and idiopathic inflammatory myopathies is an increasingly frequent entity, but the association with immune-mediated necrotizing myositis has rarely been described.
Cristina Alexandru, Anca Donisa, Florin Bobirca, Ana Maria Dascalu, Dan Dumitrescu, Ioan Ancuta, Mihai Bojinca, Ana Maria Balahura, Carmen Manea, Ionela Belaconi, Daniela Anghel, Catalin Dumitrașcu, Catalin Alius, Andreea Cristina Costea, Andrei Marin, Dragos Serban, Anca Bobircă   +16 more
doaj   +2 more sources

Statin-Induced Immune-Mediated Necrotizing Myopathy: A Case Report of a Rare and Underrecognized Cause of Progressive Weakness. [PDF]

Cureus
Statin-induced necrotizing autoimmune myopathy is a rare immune-mediated process that leads to muscle necrosis and occurs following exposure to statin therapy. The diagnostic clue for this disorder stems from the development of a proximal muscle weakness
Tangutoori S, Kommineni SS, Gullapalli D, Gudipati MK, Ganti SS.   +4 more
europepmc   +2 more sources

Emerging atypical clinicopathological manifestations of immune-mediated necrotizing myopathy (IMNM). [PDF]

Neuromuscul Disord
Skolka MP, Pinal-Fernandez I, Mammen AL, Liewluck T.   +3 more
europepmc   +2 more sources

Immune-Mediated Necrotizing Myopathy Associated With Myelodysplastic Syndrome

Annals of Internal Medicine: Clinical Cases, 2023
Autoimmune diseases can often be diagnosed in patients with myelodysplastic syndrome (MDS). Here, we review the emerging literature linking MDS and rare presentations of autoimmunity, including myositis.
Katherine M. Sheu, Benedict K. Tiong, Meika A. Fang, Ari Weinreb   +3 more
doaj   +1 more source

A Case of Anti-SRP Immune-mediated Necrotizing Myopathy Following Suspected Coxsackie B4 Infection: Exploring a Viral Trigger Hypothesis. [PDF]

J Community Hosp Intern Med Perspect
Immune-mediated necrotizing myopathy (IMNM) is a rare subtype of idiopathic inflammatory myopathies that can present with rhabdomyolysis. We report a 43-year-old woman with rapidly progressive proximal muscle weakness following a flu-like illness ...
Ahmed M, Salameh R, Salia S, Harris BT, Haas CJ, Siddiqi A.   +5 more
europepmc   +2 more sources