Results 41 to 50 of about 3,889 (160)

Immune-mediated necrotizing myopathy following vaccination with the AstraZeneca (AZD1222) COVID-19 vaccine: A case report and brief review

, 2023
Immune-Mediated Necrotizing Myopathy (IMNM) after vaccination has been reported previously, however it is rare after COVID-19 vaccination. We report the first case of IMNM two weeks after vaccination with the AstraZeneca (AZD1222) COVID-19 vaccine. There
M.A. Najafi, F. Najafi, M. Kheradmand, Kheradmand, M., B. Ansari, M.R. Najafi, Ansari, B., Najafi, M. R., Najafi, M. A., Najafi, F.   +9 more
core   +1 more source

Diagnostic utility of inflammatory markers in formalin‐fixed and paraffin‐embedded muscle biopsies for idiopathic inflammatory myopathies

Histopathology, EarlyView.
Formalin‐fixed, paraffin‐embedded (FFPE) muscle tissue supports robust immunohistochemical detection of MHC II, MxA, and p62 with performance comparable to frozen sections. This approach reliably identifies the pathological signatures of inclusion body myositis, dermatomyositis, immune‐mediated necrotizing myopathy, and overlap myositis, enhancing the ...
Chinnawut Suriyonplengsaeng, Jariya Waisayarat   +1 more
wiley   +1 more source

Calcinosis Cutis and Delayed‐Onset Myositis in a Case of Suspected Localized Scleroderma: A Diagnostic and Therapeutic Challenge

Pediatric Dermatology, EarlyView.
ABSTRACT A 16‐year‐old girl presenting with calcinosis cutis and localized scleroderma subsequently developed delayed‐onset idiopathic inflammatory myopathy five years after initial skin involvement. Despite the absence of typical dermatomyositis features and negative myositis‐specific antibodies, whole‐body MRI revealed extensive subclinical muscle ...
Edoardo Marrani, Laura Gatti, Ilaria Pagnini, Teresa Oranges, Cesare Filippeschi, Gabriele Simonini   +5 more
wiley   +1 more source

Statin-Induced Immune-Mediated Necrotizing Myopathy: An Increasingly Recognized Inflammatory Myopathy [PDF]

Cureus, 2020
Statin-induced immune-mediated necrotizing myopathy, also known as anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase (anti-HMGCR) myopathy, is an inflammatory myopathy that is triggered by statin exposure and persists after statin discontinuation. It is a rare side effect of statins, distinct from the more commonly recognized statin-induced myalgia,
Stroie, Oana P, Boster, Joshua, Surry, Luke   +2 more
openaire   +2 more sources

Diagnostic and Therapeutic Challenges in Statin‐Induced Necrotizing Autoimmune Myopathy in an Elderly Patient: A Rare Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT We present the case of a 78‐year‐old woman with metabolic syndrome and a history of multiple ischemic strokes who developed progressive symmetrical proximal muscle weakness, predominantly affecting the lower extremities, while on atorvastatin.
Nischal Shrestha, Abdirahman Hassan, Jennifer Ann Evans   +2 more
wiley   +1 more source

Ageing‐Associated Dysregulation of Myogenic Differentiation in Inclusion Body Myositis

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Skeletal muscle is a postmitotic tissue dependent on a complex and tightly regulated regeneration process involving numerous intracellular and extracellular factors, including myogenic regulatory factors (MRFs), cytokines and myokines. Quiescent satellite cells are activated by physiological stimuli, injury or other traumatic insults for the ...
Geert M. de Vries, Willem De Ridder, Jonathan Baets   +2 more
wiley   +1 more source

Isolated Oropharyngeal Dysphagia as the Initial Presentation of Anti-SRP Immune-Mediated Necrotizing Myopathy

, 2021
A 51-year-old male initially presented with a progressive course of isolated oropharyngeal dysphagia prior to the clinical course of painful symmetrical proximal muscle weakness without sensory deficit which rendered him to wheelchairbound status within ...
Thanyalak Amornpojnimman, Pat Korathanakhun   +1 more
core   +1 more source

Chronic Inflammatory Demyelinating Polyneuropathy (CIDP): A Comprehensive Review of Types, Pathophysiology, and Treatment Approaches

Brain and Behavior, Volume 16, Issue 5, May 2026.
Chronic inflammatory demyelinating polyneuropathy is an autoimmune disorder causing demyelination, leading to distal weakness, sensory loss, and autonomic dysfunction. Immune activation triggers macrophage‐mediated myelin damage and conduction failure.
Ayesha Khan, Arsal Khan, Kuldeep Dalpat Rai, Anzel Saeed, Harsh Kumar, Aneesh Kumar Sangtiani, Tehreem Fatima, Muhammad Tanveer Alam, Faiza Rajput, Sakshi Chawla, Hussain Haider Shah, Humaira Kalam   +11 more
wiley   +1 more source

Anti-3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Immune-Mediated Necrotizing Myopathy following mRNA SARS-CoV-2 Vaccination

, 2023
The new coronavirus (COVID-19) pandemic has resulted in the unprecedented production of vaccines. In this context, the possible adverse effects remain to be identified and reported.
Myrian Mathildes Sá de Deus Rocha, Maria Cristina del Negro, Maciel Eduardo de Pontes, Vinícius Viana Abreu Montanaro, Vinícius Alves Bezerra, Julio Salgado Antunes, Marta Rodrigues de Carvalho, Rubens Nelson Morato Fernandez   +7 more
core   +1 more source

Sarcoid Nodular Myopathy Presenting With Hypercalcemia: A Rare Presentation—Case Report

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT An 18‐year‐old female patient with no past medical history presented with nonanginal chest pain 2 months after her delivery. She did not report any other symptoms such as cough, dyspnea, nausea, or vomiting. Her vital signs were stable. The only positive finding on physical examination was tenderness and edema, with a palpable lump on her ...
Vahideh Sadra, Amir Bahrami, Bahareh Mehramuz, Sina Hamzehzadeh, Mahsa Malekian   +4 more
wiley   +1 more source