Results 51 to 60 of about 2,380,685 (149)

Cutaneous involvement in anti-HMGCR positive necrotizing myopathy. [PDF]

, 2021
OBJECTIVE Anti-3-Hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) positive immune-mediated necrotizing myopathy (IMNM) is a rare disease. It is induced by exogenous substances, most often by statins. Little is known about cutaneous manifestations
Peter M. Villiger, Laurence Feldmeyer, Michael P. Horn, Williams, Barbara, Barbara Williams, Horn, Michael P., Feldmeyer, Laurence, Villiger, Peter M., Banz, Yara, Yara Banz   +9 more
core   +1 more source

Treatment of Refractory Immune-Mediated Necrotizing Myopathy with Abatacept and Tacrolimus: A Case-Based Review

, 2021
Idiopathic inflammatory myopathies are characterized by muscle weakness, elevation in serum muscle enzyme levels, electromyography abnormalities, presence of Myositis Specific Autoantibodies (MSAs) and findings of inflammation on muscle biopsy.
Bhanusali, Neha, Bhanushali, Karan, Camargo Macias, Kathlyn, Ambreesh, Chawla   +3 more
core  

Seronegative Granulomatous Myositis With Bulbar Weakness and Reversible Cardiomyopathy: A Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT A 64‐year‐old woman presented with seronegative idiopathic granulomatous myositis, featuring severe bulbar weakness, reversible cardiomyopathy (ejection fraction 20%–25%), hepatic injury, and acute kidney injury. Muscle biopsy confirmed granulomatous inflammation.
Balachandran R. Vaidyanathan, Muhamed Abubacker, John Ponugupati   +2 more
wiley   +1 more source

Anti-SRP immune-mediated necrotizing myopathy: A critical review of current concepts

Frontiers in Immunology, 2022
Purpose of reviewThis review aims to describe clinical and histological features, treatment, and prognosis in patients with anti-signal recognition particle (SRP) autoantibodies positive immune-mediated necrotizing myopathy (SRP-IMNM) based on previous ...
Xue Ma, Bi-Tao Bu
doaj   +1 more source

Paraneoplastic Myopathy as a Possible Initial Presentation of Sporadic Burkitt Lymphoma in an Immunocompetent Adult: A Case Report

Cancer Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background Burkitt's lymphoma (BL) is a highly aggressive B‐cell non‐Hodgkin lymphoma with rapid proliferation and early systemic dissemination. Neuromuscular manifestations are rare and are typically secondary to direct infiltration or metabolic complications.
Abolfazl Khalafi‐Nezhad, Dena Firouzabadi, Vahid mohammadkarimi, Amirreza Dehghanian   +3 more
wiley   +1 more source

Muscle MRI in immune-mediated necrotizing myopathy (IMNM). implications for clinical management and treatment strategies [PDF]

, 2022
Objectives Immune-mediated necrotizing myopathy (IMNM) is the most severe idiopathic inflammatory myopathy (IIM) and early aggressive poly-immunotherapy is often required to reduce long-term disability.
Diaz-Manera, Jordi, Vigo, Eduard Gallardo, Garibaldi, Matteo, Costanzo, Rocco, Rossini, Elena, Tufano, Laura, Lauletta, Antonio, Leonardi, Luca, Tartaglione, Tommaso, Antonini, Giovanni, Alfieri, Girolamo, Salvetti, Marco, Merlonghi, Gioia, Universitat Autònoma de Barcelona, Vanoli, Fiammetta, Fionda, Laura, Perez, Jorge Alonso, Morino, Stefania   +17 more
core   +1 more source

Diabetic myonecrosis complicated by emphysematous pyomyositis and abscess caused by Escherichia coli: a case report

Journal of Medical Case Reports
Background Necrotizing myopathies and muscle necrosis can be caused by immune-mediated mechanisms, drugs, ischemia, and infections, and differential diagnosis may be challenging. Case presentation We describe a case of diabetic myonecrosis complicated by
Anne M. Kerola, Kari K. Eklund, Heikki Valleala, Olli Tynninen, Jaakko Helve, Ville Haapamäki, Mari Eriksson   +6 more
doaj   +1 more source

A case of seronegative immune-mediated necrotizing myopathy

Pifu-xingbing zhenliaoxue zazhi
A case of statin-induced immune necrotizing myopathy with negative autoantibodies is reported. A 67-year-old female presented with generalized weakness and limb muscle soreness for 3 months, with worsening symptoms over the past month.
CUI Lin, XIE Bingxin, ZHANG Shifa
doaj   +1 more source

Deep venous thrombosis in an individual with statin-exposed anti-SRP myopathy: case report and review of literature

Thrombosis Journal, 2021
Background Immune-mediated necrotizing myopathy (IMNM) is characterized by proximal muscle weakness, elvated serum muscle enzyme levels, myopathic electromyography findings, and necrotic muscle fiber with few inflammatory cell infiltration in muscle ...
Jiali Li, Mingming Yan, Jiao Qin, Lingyan He, Cao Dai, Rui Wen   +5 more
doaj   +1 more source

Quantitative Guanidinium CEST‐Based pH Mapping at 3 T in Healthy and Pathological Muscle

NMR in Biomedicine, Volume 39, Issue 8, August 2026.
Chemical exchange saturation transfer (CEST) enables high‐resolution pH mapping by measuring the exchange rate between guanidinium and water protons. The current method is based on the Z‐spectra fitting with Bloch–McConnell (BM) equations and allows us to detect pH variations on the order of 0.02 pH units in the very restrained pathophysiological pH ...
Valentin Henriet, Pierre‐Yves Baudin, Benjamin Marty, Marc Lapert, Harmen Reyngoudt   +4 more
wiley   +1 more source