Results 51 to 60 of about 3,889 (160)

Immune-Mediated Necrotizing Myopathy Manifesting after Five Years of Statin Therapy

, 2023
Immune-mediated necrotizing myopathy (IMNM) is an increasingly common and serious condition in which autoantibodies attack muscle fibers causing clinically significant muscle weakness, fatigue, and myalgias.
Elizabeth C. Brewer, Francis Fischer, Dylan Lopez, Nathan G. DeRon   +3 more
core   +1 more source

Increasing incidence of immune-mediated necrotizing myopathy:single-centre experience [PDF]

, 2015
OBJECTIVES: Immune-mediated necrotizing myopathy (IMNM) is characterized by the predominant presence of necrotic muscle fibres in muscle biopsy and variable response to immunosuppressive treatment.
Zámečník, Josef, Mann, Heřman, Vencovský, Jiří, Klein, Martin, Pleštilová, Lenka, Betteridge, Zoe, McHugh, Neil   +6 more
core   +1 more source

The Role of Extracorporeal Membrane Oxygenation in Cardiopulmonary Dysfunction Due to Rheumatologic Diseases: A Systematic Review

ACR Open Rheumatology, Volume 8, Issue 4, April 2026.
Objective This systematic review documents the current status of extracorporeal membrane oxygenation (ECMO) use in patients with complications of rheumatologic diseases. Methods Following Preferred Reporting Items for Systematic Reviews and Meta Analyses 2020 guidelines, we conducted a systematic review of studies published from January 2019 to ...
Kari L. Falaas, Lyubov Y. Tiegs, Nicole Theis‐Mahon, Elie Gertner   +3 more
wiley   +1 more source

Immune-mediated necrotizing myopathy: an emerging disorder

Neurología (English Edition)
To describe the main features and the clinical management of a cohort of patients with immune-mediated necrotizing myopathy (IMNM).We conducted an observational, monocentric, retrospective study of IMNM patients diagnosed in the Neuromuscular Unit of a tertiary hospital in Madrid (Spain) between 2013 and 2021.Sixteen IMNM cases were diagnosed, with a ...
S, Portela-Sánchez, I, Catalina, S, López Muñoz, A, Lozano Ros, A, Sánchez-Soblechero, E, Sola Vendrell, P, Sánchez-Mateos, J L, Muñoz-Blanco   +7 more
openaire   +2 more sources

Image_1_Characteristics of cardiac involvement in immune-mediated necrotizing myopathy.jpeg

, 2023
ObjectiveTo investigate the characteristics of cardiac involvement due to Immune-mediated Necrotizing Myopathy (IMNM).MethodsPatients diagnosed with Immune-mediated Necrotizing Myopathy (IMNM) who attended the Department of Neurology and the Department ...
Qiang Shi (191722), Mengyang Liu (3074763), Ying Lin (16144), Juan Chen (61123), Lingya Qiao (14686966)   +4 more
core   +1 more source

Clinicopathologic Characterization of Muscle Biopsy Findings in Overlap Myositis: A Single Tertiary Care Center Experience

Immunity, Inflammation and Disease, Volume 14, Issue 4, April 2026.
ABSTRACT Objective This study aims to describe the muscle biopsy features of overlap myositis (OM) and compare them with other inflammatory myopathies. We analyzed clinical, serological findings, and histopathological patterns in muscle biopsies to understand the features of OM.
Sidra Fatima, Megha Uppin, Liza Rajasekhar, Reshma Sultana Shaik, Derin Mary Thomas, Phani Kumar Devarasetti   +5 more
wiley   +1 more source

Table_1_Characteristics of cardiac involvement in immune-mediated necrotizing myopathy.docx

, 2023
ObjectiveTo investigate the characteristics of cardiac involvement due to Immune-mediated Necrotizing Myopathy (IMNM).MethodsPatients diagnosed with Immune-mediated Necrotizing Myopathy (IMNM) who attended the Department of Neurology and the Department ...
Qiang Shi (191722), Juan Chen, Mengyang Liu, Mengyang Liu (3074763), Ying Lin (16144), Qiang Shi, Juan Chen (61123), Ying Lin, Lingya Qiao, Lingya Qiao (14686966)   +9 more
core   +1 more source

Application and Challenges of Chimeric Antigen Receptor T Cell Therapy in Systemic Rheumatic Diseases and Autoimmune Disorders

MedComm, Volume 7, Issue 4, April 2026.
CAR‐T cell therapy in systemic rheumatic diseases and autoimmune disorders. (This figure was created using BioRender.com.) ABSTRACT Chimeric antigen receptor T (CAR‐T) cell therapy, originally developed for hematologic malignancies, has emerged as a transformative candidate for systemic rheumatic diseases and autoimmune disorders (AIDs).
Zhidan Fan, Li Zhang, Haiguo Yu
wiley   +1 more source

Myasthenia gravis following the initiation of statin therapy: A multinational self‐controlled case series study

Journal of Internal Medicine, Volume 299, Issue 4, Page 502-514, April 2026.
Abstract Background Evidence regarding the risk of new‐onset myasthenia gravis (MG) following statin therapy initiation is limited. Objectives To investigate this potential adverse effect using multinational real‐world population‐based data. Methods A self‐controlled case series (SCCS) study was conducted using electronic medical records and claims ...
Vincent Ka Chun Yan, Wanchun Xu, Yuta Taniguchi, Kwun Kei Fung, Koon Ho Chan, Gary Kui Kai Lau, Celine Sze Ling Chui, Francisco Tsz Tsun Lai, Xue Li, Masao Iwagami, Rie Masuda, Nanako Tamiya, Sreemanee Raaj Dorajoo, Jing Wei Neo, Esther Wai Yin Chan, Ian Chi Kei Wong, Eric Yuk Fai Wan   +16 more
wiley   +1 more source

Immune Mediated Necrotizing Myopathy: a Cause of Isolated Myopathy of Neck Extensor Muscle [PDF]

Clinical Medicine & Research, 2016
Immune mediated necrotizing myopathy (IMNM) is a unique form of myositis that is characterized by distinct muscle biopsy features including abundant myofiber necrosis, degeneration, and regeneration with only minimal, if any, inflammation on muscle biopsy.
Rahul, Sehgal, Rafael, Medina-Flores, Ralph, Yachoui, Charles V, Kenney   +3 more
openaire   +2 more sources