Results 71 to 80 of about 2,380,685 (149)
ABSTRACT We report a case of a kidney transplant recipient who presented with generalised muscle pain, weakness and brown urine discoloration in the setting of acute severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection. Investigations demonstrated rhabdomyolysis with elevated creatine kinase levels and severe acute kidney injury (AKI).
Navya Kataria +8 more
wiley +1 more source
ABSTRACT We present the case of a 78‐year‐old woman with metabolic syndrome and a history of multiple ischemic strokes who developed progressive symmetrical proximal muscle weakness, predominantly affecting the lower extremities, while on atorvastatin.
Nischal Shrestha +2 more
wiley +1 more source
Immune-mediated necrotizing myopathy (IMNM), one of the major subtypes of idiopathic inflammatory myopathy, exhibits considerable clinical heterogeneity. The condition’s etiology is autoimmune, yet myopathology reveals prominent muscle fiber necrosis and
De Bleecker, Jan, De Paepe, Boel
core
ABSTRACT SAPHO syndrome is a rare autoinflammatory disorder characterized by synovitis, acne, pustulosis, hyperostosis, and osteitis. Although musculoskeletal and dermatologic manifestations are well recognized, extra‐articular involvement remains uncommon, particularly muscular inflammation.
Farah Jaafar Mahdi +7 more
wiley +1 more source
Immune-mediated necrotizing myopathy in a multi-ethnic Malaysian cohort
Objective: To describe the clinical features and treatment outcomes of immune-mediated necrotizing myopathy (IMNM) in Malaysian patients. Methods: We describe a cohort of IMNM patients from a tertiary medical centre in Kuala Lumpur, Malaysia, in terms of
Tan, Cheng Yin +8 more
core
ABSTRACT Background Pembrolizumab, an anti‐PD‐1 immune checkpoint inhibitor, has transformed the treatment of multiple solid tumors. However, it can rarely cause immune‐related myositis, which may involve limb, bulbar, and respiratory muscles, posing a risk of severe morbidity and mortality. Early recognition and management are essential. We report two
Francesca Rifaldi +5 more
wiley +1 more source
Challenges in Treating Statin-Associated Necrotizing Myopathy
Myalgia and mild elevation in muscle enzymes are common side effects of statin therapy. While these symptoms are generally self-limited, in rare cases, statin use is associated with an immune-mediated necrotizing myopathy caused by development of ...
Michael Lucke +5 more
core +1 more source
Statin-induced necrotizing myositis is increasingly being recognised as part of the "statin-induced myopathy spectrum". As in other immune-mediated necrotizing myopathies, statin-induced myositis is characterised by proximal muscle weakness with marked ...
Hamann, Philip D H +3 more
core +1 more source
Necrotizing autoimmune myopathy
PURPOSE OF REVIEW: Necrotizing autoimmune myopathy (NAM) is a relatively newly recognized subgroup of idiopathic inflammatory myopathies, which despite diverse causes, have the common histopathological features of myocyte necrosis without significant ...
Liang, C. +3 more
core +1 more source
Are autoantibodies pathogenic in necrotizing myopathy?
What causes muscle fibre necrosis in necrotizing myopathy? The authors of a new study propose that specific autoantibodies contribute to disease via immune-mediated processes; but given that these processes also occur in muscular dystrophies, how likely ...
Dalakas, Marinos C.
core +1 more source

