Results 71 to 80 of about 5,602 (207)

A case of seronegative immune-mediated necrotizing myopathy

Pifu-xingbing zhenliaoxue zazhi
A case of statin-induced immune necrotizing myopathy with negative autoantibodies is reported. A 67-year-old female presented with generalized weakness and limb muscle soreness for 3 months, with worsening symptoms over the past month.
CUI Lin, XIE Bingxin, ZHANG Shifa
doaj   +1 more source

Deep venous thrombosis in an individual with statin-exposed anti-SRP myopathy: case report and review of literature

Thrombosis Journal, 2021
Background Immune-mediated necrotizing myopathy (IMNM) is characterized by proximal muscle weakness, elvated serum muscle enzyme levels, myopathic electromyography findings, and necrotic muscle fiber with few inflammatory cell infiltration in muscle ...
Jiali Li, Mingming Yan, Jiao Qin, Lingyan He, Cao Dai, Rui Wen   +5 more
doaj   +1 more source

Isolated Oropharyngeal Dysphagia as the Initial Presentation of Anti-SRP Immune-Mediated Necrotizing Myopathy

Journal of Health Science and Medical Research (JHSMR), 2021
A 51-year-old male initially presented with a progressive course of isolated oropharyngeal dysphagia prior to the clinical course of painful symmetrical proximal muscle weakness without sensory deficit which rendered him to wheelchairbound status within ...
Pat Korathanakhun, Thanyalak Amornpojnimman   +1 more
doaj   +1 more source

Ubiquitin Proteasom System und Myopathien [PDF]

, 2015
Objective: In idiopathic inflammatory myopathies (IIM) infiltration of immune cells into muscle and upregulation of MHC-I expression implies increased antigen presentation and involvement of the proteasome system.
Ghannam, Khetam
core   +1 more source

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, Volume 13, Issue 14, 9 March 2026.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source

Diabetic myonecrosis complicated by emphysematous pyomyositis and abscess caused by Escherichia coli: a case report

Journal of Medical Case Reports
Background Necrotizing myopathies and muscle necrosis can be caused by immune-mediated mechanisms, drugs, ischemia, and infections, and differential diagnosis may be challenging. Case presentation We describe a case of diabetic myonecrosis complicated by
Anne M. Kerola, Kari K. Eklund, Heikki Valleala, Olli Tynninen, Jaakko Helve, Ville Haapamäki, Mari Eriksson   +6 more
doaj   +1 more source

Statin-Associated Autoimmune Myopathy: Current Perspectives

Therapeutics and Clinical Risk Management, 2020
Eleni Tiniakou Johns Hopkins University School of Medicine, Department of Medicine, Division of Rheumatology, Baltimore, MD, USACorrespondence: Eleni TiniakouJohns Hopkins University School of Medicine, 5200 Eastern Avenue, Mason Lord, Center Tower ...
Tiniakou E
doaj  

Anti-Signal Recognition Particle Myopathy in a Geriatric Patient

European Journal of Case Reports in Internal Medicine, 2015
Anti-signal recognition particle (SRP) myopathy is a rare idiopathic inflammatory myositis that usually affects middle-age women, and is characterized by rapidly progressive proximal and symmetrical muscle weakness, elevated creatine kinase levels ...
Diana Marques Ferreira, Patrícia Afonso Mendes, António Aragão, Manuel Teixeira Veríssimo, Armando Carvalho   +4 more
doaj   +1 more source

Anti-3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Immune-Mediated Necrotizing Myopathy following mRNA SARS-CoV-2 Vaccination

Case Reports in Neurological Medicine, 2023
The new coronavirus (COVID-19) pandemic has resulted in the unprecedented production of vaccines. In this context, the possible adverse effects remain to be identified and reported.
Marta Rodrigues de Carvalho, Myrian Mathildes Sá de Deus Rocha, Vinícius Alves Bezerra, Maciel Eduardo de Pontes, Maria Cristina del Negro, Julio Salgado Antunes, Vinícius Viana Abreu Montanaro, Rubens Nelson Morato Fernandez   +7 more
doaj   +1 more source

Dermatomyositis Like Presentation of Anti‐HMGCR Immune Mediated Necrotising Myopathy

JEADV Clinical Practice, Volume 5, Issue 1, Page 237-240, March 2026.
Capsule summary Cutaneous manifestations of HMGCR‐IMNM are rare and poorly described. Dermatomyositis‐like rash manifestation can be a presentation of the HMGCR‐IMNM. We report a case with a dermatomyositis‐like presentation and provide a literature review on this topic.
Lionel Leblanc, Lyna Mtimet, Louis Wolff, Evelyne Berlingin, Bruno Couturier   +4 more
wiley   +1 more source