Results 91 to 100 of about 3,889 (160)

632: Statins may initiate a persisting immune-mediated myopathy and myositis: A study of 10 cases

, 2007
Background: Statins may cause a necrotising myopathy and hyperCKaemia which are usually reversible once the drug is discontinued. Aim: To investigate the muscle pathology in a group of 10 patients who developed myopathic symptoms during statin therapy
Zilko, P., Needham, M., Lamont, P., Fabian, V., Panegyres, P., Mastaglia, F., Knezevic, W.   +6 more
core  

"STATINS KALEIDOSCOPE". MYOPATHY FROM STATINS

, 2019
Statins are medications that inhibit the 3-hydroxy-3-methylglutaryl-CoA reductase enzyme, thus inhibiting cholesterol biosynthesis. Statins reduce cardiovascular risk and morbidity in patients with coronaropathia, however, without forgetting their side ...
NUHAJ, LEDIANA, ZOTO, ARTUR, RAPUSHI, ERVIN, BACKA, TEUTA, XHEMALI, INDIN   +4 more
core  

Fatal Cardiomyopathy Secondary to Seronegative Immune-Mediated Necrotizing Myopathy: A Case Report. [PDF]

Am J Case Rep
Lueck BD, Maclean AKW, El Hasbani G, Layman AJ, Ernste FC, Arment CA.   +5 more
europepmc   +1 more source

Statin-Associated Immune-Mediated Necrotizing Myopathy Presenting as Persistent Hypertransaminasemia. [PDF]

Cureus
Bragança R, Ferreira da Silva N, Macedo Brás E.   +2 more
europepmc   +1 more source

Statin-Associated Immune-Mediated Necrotizing Myopathy: An Underrecognised Cause of Progressive Muscle Weakness in Primary Care. [PDF]

Cureus
Ong JT, Jamil TR, Loo SY.
europepmc   +1 more source

Anti-3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase (HMGCR) Immune-Mediated Necrotizing Myopathy With Subsequent Diagnosis of Mantle Cell Lymphoma. [PDF]

Cureus
Zhao C, Duffield A, Toz B.
europepmc   +1 more source

Novel phenotypes of immune-mediated necrotizing myopathy identified independent of myositis-specific antibody specificity that improve prognostic stratification. [PDF]

Front Immunol
Wei X, Sun H, Pang Z, Bai N, Guo T, Nie C, Yang X, Lu Z, Bao L, Miao J, Yu X.   +10 more
europepmc   +1 more source

A Rare Case of Anti-HMGCR-Positive Immune-Mediated Necrotizing Myopathy Associated With Statin Use. [PDF]

Cureus
Okoli ML, Okoli IC, Anasobi RT, Okoli AC, Madueke AF, Okoli IC.   +5 more
europepmc   +1 more source

Complement-mediated muscle cell lysis: A possible mechanism of myonecrosis in anti-SRP associated necrotizing myopathy (ASANM)

, 2013
The mechanism of necrotizing myopathy associated with antibodies to signal recognition particle (SRP) remains unclear. We investigated the effect of anti-SRP + serum and complement on cell viability in myoblast cultures.
Bundell, C., Mastaglia, F.L., Price, L., Fabian, V., Rojana-udomsart, A., Mitrpant, C., Wilton, S.D., Luo, Y-B, Hollingsworth, P.   +8 more
core  

Immune-Mediated Necrotizing Myopathy Diagnosis and Flare in an Adolescent After COVID-19 Vaccine. [PDF]

Clin Case Rep
Hoffman P, Chefitz E, Salvant C, Horton DB.   +3 more
europepmc   +1 more source