Results 91 to 100 of about 5,602 (207)
ABSTRACT Background Monoclonal gammopathy‐associated myopathies (MGAMs) include light chain (AL) amyloid myopathy, sporadic late‐onset nemaline myopathy (SLONM), and vacuolar myopathy with monoclonal gammopathy and stiffness (VAMMGAS). These subtypes usually occur separately, although rare overlap has been described. We report a patient with monoclonal
Felipe J. S. Jones +4 more
wiley +1 more source
Rheumatic conditions in human immunodeficiency virus infection [PDF]
Many rheumatic diseases have been observed in HIV-infected persons. We, therefore, conducted a comprehensive literature search in order to review the prevalence, presentation and pathogenesis of rheumatic manifestations in HIV-infected subjects ...
Daikeler, T., Tyndall, A., Walker, U. A.
core
Objective Interstitial lung disease (ILD) is common in idiopathic inflammatory myositis (IIM), particularly in antisynthetase syndrome (ASyS), antimelanoma differentiation‐associated protein 5 (anti‐MDA5) syndrome, and scleromyositis. ILD can progress despite resolution of extrapulmonary symptoms, termed postmyopathic progressive pulmonary fibrosis ...
Julia Clark +5 more
wiley +1 more source
Pulse Steroid Therapy in a Patient With Refractory Rhabdomyolysis of Unknown Etiology: A Case Report
ABSTRACT Rhabdomyolysis is conventionally treated with aggressive fluid resuscitation and elimination of the inciting factor, whereas corticosteroids are typically limited to cases of immune‐mediated myopathy. We describe an 18‐year‐old female who developed profound bilateral lower‐limb swelling, bullae formation, and motor weakness following a viral ...
Mustafa Majid +10 more
wiley +1 more source
A novel therapeutic strategy for pancreatic neoplasia using a novel RNAi platform targeting PDX-1 [PDF]
Bi-functional shRNA (bi-shRNA), a novel RNA interference (RNAi) effector platform targeting PDX-1 utilizing a systemic DOTAP-Cholesterol delivery vehicle, was studied in three mouse models of progressive pancreatic neoplasia.
Charles Brunicardi +13 more
core +1 more source
Selenium deficiency impairs host innate immune response and induces susceptibility to infection [PDF]
Background Susceptibility or resistance to infection with Listeria monocytogenes correlates with Selenium (Se) deficiency in response to infection. Results Se-deficient mouse models of listeriosis were used to study the innate immune response during the ...
Wei Lei +6 more
core +1 more source
A 67‐year‐old man with cryptogenic organising pneumonia developed recurrent relapses despite corticosteroid and mycophenolate therapy. A complete absence of mannose‐binding lectin was identified, suggesting impaired apoptotic cell clearance as a contributor to persistent inflammation.
Ilias E. Dimeas +4 more
wiley +1 more source
An atomic view of the NFIX–DNA complex reveals recognition of the TGGCA motif and links sequence‐specific binding to the transcriptional programs governing skeletal muscle development and disease. ABSTRACT Skeletal muscle is essential for voluntary movement and exhibits a remarkable capacity for regeneration following injury.
Ci Zhu +11 more
wiley +1 more source
Autoimmune diseases and pregnancy: analysis of a series of cases [PDF]
BACKGROUND: An autoimmune disease is characterized by tissue damage, caused by self-reactivity of different effector mechanisms of the immune system, namely antibodies and T cells.
Alexandra Mesquita +31 more
core +2 more sources
Immune-mediated necrotizing myopathy [PDF]
Tomáš Kalous, Josef Zámečník
openaire +1 more source

