Results 201 to 210 of about 26,633 (217)
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Human Physiology, 2018
In recent years, there has been an increasing interest in myostatin, a hormone that inhibits the growth and differentiation of muscle tissue. This interest is associated with an increase in the amount of data on the spectrum of the myostatin functioning.
D. S. Kostyunina +2 more
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In recent years, there has been an increasing interest in myostatin, a hormone that inhibits the growth and differentiation of muscle tissue. This interest is associated with an increase in the amount of data on the spectrum of the myostatin functioning.
D. S. Kostyunina +2 more
openaire +1 more source
Myostatin inhibits differentiation of bovine preadipocyte
Domestic Animal Endocrinology, 2007We investigated the effect of myostatin on the differentiation of bovine preadipocyte. Stromal-vascular cells containing preadipocytes were prepared from perirenal adipose tissue of approximately 30-month-old Japanese Black steers. After confluence, the differentiation was induced by 1-methyl-3-isobutyl-xanthine, dexamethasone, insulin, and ...
Shizuka, Hirai +5 more
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Myostatin in Muscle Growth and Repair
Exercise and Sport Sciences Reviews, 2001Myostatin, a member of the TGF beta superfamily, regulates skeletal muscle size by controlling embryonic myoblast proliferation. Recent results show that myostatin may also have a role in muscle regeneration and muscle wasting of adult animals. This review summarizes the recent developments in the regulation of myostatin gene expression and mechanism ...
M, Sharma +3 more
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Prolonged absence of myostatin reduces sarcopenia
Journal of Cellular Physiology, 2006AbstractSarcopenia is a progressive age‐related loss of skeletal muscle mass and strength. Parabiotic experiments show that circulating factors positively influence the proliferation and regenerative capacity of satellite cells in aged mice. In addition, we believe that negative regulators of muscle mass also serve to balance the signals that influence
Victoria, Siriett +5 more
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Myostatin regulation during skeletal muscle regeneration
Journal of Cellular Physiology, 2000Myostatin, a member of the TGF-beta superfamily, is a key negative regulator of skeletal muscle growth. The role of myostatin during skeletal muscle regeneration has not previously been reported. In the present studies, normal Sprague-Dawley and growth hormone (GH)-deficient (dw/dw) rats were administered the myotoxin, notexin, in the right M.
S, Kirk +5 more
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Muscle regeneration through myostatin inhibition
Current Opinion in Rheumatology, 2005Myostatin is an endogenous, negative regulator of muscle growth. Selective inhibition of myostatin may have broad clinical utility by improving regeneration in diverse and burdensome muscle disorders. An understanding of this potential is relevant because inhibitors of myostatin have recently entered clinical trials.This article reviews the structure ...
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Craniofacial Morphology in Myostatin-deficient Mice
Journal of Dental Research, 2007GDF-8 (myostatin) is a negative growth regulator of skeletal muscle, and myostatin-deficient mice are hypermuscular. Muscle size and force production are thought to influence growth of the craniofacial skeleton. To test this relationship, we compared masticatory muscle size and craniofacial dimensions in myostatin-deficient and wild-type CD-1 control ...
L, Vecchione +6 more
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Myostatin: an overlooked player in heart failure?
European Journal of Heart Failure, 2010Sillje, Herman H. W., de Boer, Rudolf A.
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