Reproducible Molecular Subtypes in Systemic Lupus Erythematosus Are Associated With Disease Activity, Serology, and Distinct Trajectories Over Time. [PDF]
Objective Systemic lupus erythematosus (SLE) is biologically heterogeneous, motivating development of reproducible molecular subtypes that can track change over time. The aim of this study was to establish a reproducible molecular stratification of SLE across cohorts and platforms and connect the resulting subtypes to clinical activity, serology, and ...
Seridi L +7 more
europepmc +2 more sources
Interaction of Functional Brain Networks Is Associated With k-Clique Percolation in the Human Structural Connectome. [PDF]
Clique percolation of an anomalously high order in the structural connectome reflects the interaction of functional brain networks. The observed structural organization reveals a high local connectivity density while maintaining overall network sparsity.
Tiselko V +4 more
europepmc +2 more sources
The key task of the article is to assess the ability to convert resources into other resources and capital in accordance with the logic of Marxist methodology. Resources are any elements of reality that serve to provide social activities, so all the resources are social in the broadest sense of the word. A resource can turn into capital or cannot turn,
A A Chernega
openaire +2 more sources
Circadian Disruptions in the Myshkin Mouse Model of Mania Are Independent of Deficits in Suprachiasmatic Molecular Clock Function. [PDF]
BACKGROUND: Alterations in environmental light and intrinsic circadian function have strong associations with mood disorders. The neural origins underpinning these changes remain unclear, although genetic deficits in the molecular clock regularly render ...
HR Sanghani (21880388) +10 more
core +6 more sources
Adaptation, Activism, and the Looming Climate Disaster†
Abstract It is likely that the process of global climate change will continue to accelerate. There is a lack of political will to confront the problem and the consequences for humanity — including widespread suffering and institutional destabilization — will be disastrous. How should educators respond to a catastrophic future?
Bryan R. Warnick
wiley +1 more source
A Partial Hierarchical Model for Online Low‐Resolution Wear Particle Images Classification
Wear particle image analysis is an effective method to detect wear condition of mechanical devices. However, the recognition accuracy and recognition efficiency for online wear particle automatic recognition are always mutual restricted because the online wear particle images have almost no texture information and lack clarity. Especially for confusing
Xuxu Guo +9 more
wiley +1 more source
Prince Myshkin (The Idiot): the falling sickness, The Gambler, and 'The Grand Inquisitor'. [PDF]
Fyodor Dostoevsky (1821–1881). Dostoevsky was one of the greatest writers of the 19th century, who overcame both physical and mental problems in pursuit of his art. His writing is characterised by interwoven psychological, religious, and existential themes.
Brooks J.
europepmc +4 more sources
DOSTOEVSKY’S INSIGHTS: FROM PRINCE MYSHKIN TO VL. SOLOVYOV [PDF]
F. M. Dostoevsky foresaw many crises and shocks, development of various ideological diseases in people and the society. The writer’s providentialism also manifested itself in the fact that in Prince Myshkin he “prophesied” the personality of his younger contemporary Vl. Solovyov to Russia. The article analyzes affinity of the literary character and the
Aleksandr Petrovich Vlaskin +2 more
openaire +1 more source
ON ONE MODEL INTEGRAL-DIFFERENTIAL BERNULL EQUATION [PDF]
The model integro-differential Bernlulli equation is considered in the paper. This equation was reduced to a differential equation with derivatives of fractional orders and solved numerically with the help of Newton’s iteration method.
Myshkin S.V.
doaj +1 more source
Deficits in social behavioral tests in a mouse model of alternating hemiplegia of childhood. [PDF]
Social behavioral deficits have been observed in patients diagnosed with alternating hemiplegia of childhood (AHC), rapid-onset dystonia-parkinsonism and CAPOS syndrome, in which specific missense mutations in ATP1A3, encoding the Na+, K+-ATPase α3 ...
Kirshenbaum GS +4 more
europepmc +2 more sources

