Results 61 to 70 of about 4,124 (180)

Causal Association Between Thyroid Function and Myeloproliferative Disease: A Two‐Sample Mendelian Randomization Study

International Journal of Endocrinology, Volume 2026, Issue 1, 2026.
Background Thyroid dysfunction has been linked to hematologic abnormalities, but whether thyroid function has a causal role in myeloproliferative diseases (MDs), including chronic myeloproliferative disease (CMD), remains unclear. We used Mendelian randomization (MR) to assess the potential causal effects of thyroid‐related traits on MD risk. Methods A
Jingjing Xiang, Jun Yan, Jianping Shen, Mengke Mao, Zhiyin Zheng, Shu Deng, Sreeja Dattachoudhury   +6 more
wiley   +1 more source

Determinants of Antimicrobial Resistance in Acinetobacter baumannii Isolates From Intensive Care Patients in Latvia

International Journal of Microbiology, Volume 2026, Issue 1, 2026.
Background Acinetobacter baumannii is a leading nosocomial pathogen in intensive care units (ICUs), often resistant to multiple antibiotics. Data from the Baltic region remain scarce, limiting infection control and stewardship strategies. Methods We conducted an integrated phenotypic–genotypic analysis of A.
Mihails Dolgusevs, Nityanand Jain, Oksana Savicka, Reinis Vangravs, Jevgenijs Bodrenko, Liene Ostele-Cešķe, Gustavs Rindžs, Dace Zemite, Aigars Reinis, Baiba Rozentale, Divakar Sharma   +10 more
wiley   +1 more source

Evolving Real‐World Data and Evidence Use for New Drugs and Regenerative Medical Products Approvals in Japan—An Analysis of the 6‐Year Trend

Clinical Pharmacology &Therapeutics, Volume 118, Issue 6, Page 1405-1421, December 2025.
Several regulatory initiatives have been made to clarify the acceptability and requirements of real‐world data and real‐world evidence (RWD/E) for the benefit/risk assessment of new medical products in Japan. The objectives of this review were to characterize the use of RWD/E in regulatory applications of new medical products and to describe the ...
Suguru Okami, Kako Shimotsumagari, Yasunari Sadatsuki   +2 more
wiley   +1 more source

Effects of Hypothyroidism on the Extracellular Matrix of the Vocal Folds of Adult Female Rats

Otolaryngology–Head and Neck Surgery, Volume 173, Issue 6, Page 1448-1454, December 2025.
Abstract Objective The aim of the present study was to investigate the changes in the extracellular matrix of the vocal folds of female rats after induction of hypothyroidism. Study Design Prospective and experimental study. Setting Single tertiary center.
Welber C. Mororó, Karine V. G. de Oliveira, Jônatas B. do Amaral, Gisele Giannocco, João R. M. Martins, Noemi G. De Biase   +5 more
wiley   +1 more source

Two Deadly Complications of Untreated Hypothyroidism: Sudden Cardiac Arrest and Acute Coronary Syndrome

Endocrinology Research and Practice, 2023
Myxedema coma is a rare but life-threatening endocrinological emergency condition that may present with serious conditions such as sudden cardiac arrest or acute coronary syndrome. In this context, 2 cases are presented in this case report as examples of
Esma Pehlivan Köroğlu, Hatice Özışık, Fatih Tamnik, Mehmet Uyar, Mehmet Erdoğan   +4 more
doaj  

Spasmodic Dysphonia

World Journal of Otorhinolaryngology - Head and Neck Surgery, Volume 11, Issue 4, Page 548-567, December 2025.
ABSTRACT Spasmodic dysphonia is a laryngeal dystonia that can present as adductor, abductor, or mixed types, with or without tremor. The etiology is not understood fully. Comprehensive evaluation is required to establish the diagnosis. Treatments include voice therapy, medications, botulinum toxin injection, laryngeal surgery, deep brain stimulation ...
Aaron J. Jaworek, Robert T. Sataloff
wiley   +1 more source

Routine Treatment-Resistant Clostridium difficile Infection during Recovery from Myxedema

Case Reports in Gastroenterology, 2017
Development of the extreme form of hypothyroidism defined as myxedema is very rare. Acute symptoms and their management have been described in detail previously. However, not much attention has been devoted to therapeutic challenges that are faced in the
Jan K. Adamski, Björn B. Jäschke, Raija S. Uusitalo-Seppälä, Kalle V.J. Moilanen, Antti V. Pehkonen, Wojciech Weigl   +5 more
doaj   +1 more source

Management of Primary Adrenal Insufficiency and Overt Hypothyroidism in an HIV‐Positive Patient in a Resource‐Limited Setting: A Case Report

Clinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT In resource‐limited settings, clinicians must maintain a high index of suspicion for primary adrenal insufficiency and hypothyroidism in HIV‐positive patients presenting with non‐specific symptoms. Relying on clinical judgment and response to treatment is crucial when confirmatory tests are unavailable.
Majani Edward, Witness John, Dominick M. Raphael   +2 more
wiley   +1 more source

From Resistance to Relief: IV Levothyroxine in Refractory Hypothyroidism Management

Clinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT This case report details the clinical scenario of a 27‐year‐old female patient diagnosed with idiopathic refractory hypothyroidism. Despite adherence to prescribed oral levothyroxine therapy, she continued to experience persistent symptoms such as fatigue and cold intolerance.
Mohammad Amro, Elias Edward Lahham, Ahmed Jalal Sawafta, Motaz Saifi, Nooreddin Saifi, Fadi Atrash, Salem Billan   +6 more
wiley   +1 more source

Isolated Unilateral Pleural Effusion Associated With Hypothyroidism: A Case Report and Review of the Literature

Respirology Case Reports, Volume 13, Issue 11, November 2025.
Hypothyroidism rarely causes isolated pleural effusion, as such effusions are typically associated with comorbidities like heart failure or malignancy. This report presents a case of borderline transudative pleural effusion attributed solely to hypothyroidism after thorough differential diagnosis. Hypothyroidism should be considered in the differential
Hesam Amini, Fereshteh Attaran, Sara Soltanmohammadi   +2 more
wiley   +1 more source