Pretibial myxedema in Grave's disease: A case report and treatment review of the literature [PDF]
Clinical Case Reports (discontinued)Key Clinical Message Pretibial myxedema is a rare skin lesion in Grave's disease, which required topical glucocorticoid administration in long‐term treatment. The patient's lesion has shrunk and become flatter than before treatment. Abstract We present a
Van Bang Nguyen, Trang Vo
exaly +5 more sources
Graves' disease complicated by concurrent thyroid eye disease and pretibial myxedema successfully treated with teprotumumab [PDF]
Clinical Case Reports (discontinued), 2022 We report a 51‐year‐old woman with thyroid eye disease and biopsy‐proven pretibial myxedema that was subsequently treated with teprotumumab with improvement.
Mohamed K M Shakir +2 more
exaly +4 more sources
Successful therapeutic approach in a patient with elephantiasic pretibial myxedema [PDF]
Anais Brasileiros De Dermatologia, 2020 Localized pretibial myxedema is a dermopathy whose treatment is a challenge in dermatology, occurring in 0.5-4% of patients with Graves’ disease. This autoimmune thyroid condition stimulates the production of hyaluronic acid and glycosaminoglycans that ...
Marina Ferreira +2 more
exaly +4 more sources
Integrated multi-platform metabolomics reveals fatty acid-mediated inflammatory signatures in pretibial myxedema [PDF]
Frontiers in EndocrinologyContextPretibial myxedema (PTM) is a refractory autoimmune dermopathy associated with Graves’ disease. Although metabolic dysregulation has been recognized in thyroid-associated disorders, the metabolic profile and its functional role in PTM remain ...
Xiaoying Chen, Jiayi Cai
exaly +4 more sources
A case of pretibial myxedema treated with teprotumumab [PDF]
JAAD Case Reports, 2021 Lauren Petit, MD +3 more
exaly +4 more sources
Resolution of Thyroid Acropachy in a Patient Treated With Teprotumumab: A Case Report and Review of Mechanisms [PDF]
Case Reports in EndocrinologyGraves’ disease is an autoimmune thyroidopathy associated with hyperthyroidism and nonendocrine manifestations such as thyroid eye disease (TED), pretibial myxedema, and thyroid acropachy.
Soumya Chatterjee
doaj +3 more sources
Pretibial myxedema in a patient with HIV and hypothyroid to hyperthyroid transformation [PDF]
JAAD Case Reports, 2023 Marcia Driscoll, Shealinna Ge
exaly +4 more sources
Pretibial myxedema in a euthyroid patient: a case report [PDF]
Thyroid Research, 2021 Background Pretibial myxedema also known as localized myxedema, thyroid dermopathy, or infiltrative dermopathy and rarely as localized mucinosis is an infrequent manifestation of Graves’ disease.
Rediet Ambachew +6 more
doaj +2 more sources
Pretibial myxedema-like lesions in a 74-Year-old male with lepromatous leprosy and type 2 lepra reaction [PDF]
BMC Infectious DiseasesBackground Leprosy is a chronic infectious disease with diverse clinical manifestations. Skin lesions may present as erythema, nodules, ulcers, bullae, or verrucous hyperplasia.
Xiaorui Zhang +2 more
doaj +2 more sources
Local immune microenvironment of skin may play an important role in the development of pretibial myxedema. [PDF]
Exp Dermatol, 2021 Abstract Pretibial myxedema (PTM), characterized by the accumulation of glycosaminoglycans in dermis is an autoimmune skin disorder, which is almost always associated with Graves’ disease (GD). Although fibroblast stimulated by thyroid‐stimulating hormone receptor (TSHR) antibody, cytokines and growth factors have been postulated as target of the ...
Chen X +6 more
europepmc +2 more sources