Results 71 to 80 of about 10,856 (235)

Management of Maternal Hypothyroidism in Pregnancy: A Danish Regional Study

Clinical Endocrinology, Volume 103, Issue 2, Page 269-276, August 2025.
ABSTRACT Objective Hypothyroidism in pregnant women must be carefully managed to prevent complications. The aim of this study was to evaluate compliance with clinical recommendations for the monitoring and treatment of hypothyroidism in pregnant women and to assess the clinical action upon each biochemical monitoring at different time points in ...
Karoline Schack, Line Meyer Laustsen, Randi Ziska Sørensen, Maja Hjelm Lundgaard, Nanna Maria Uldall Torp, Jesper Karmisholt, Stine Linding Andersen   +6 more
wiley   +1 more source

Anti‐Ro52/TRIM21 autoantibodies predict Sjögren's syndrome in patients with primary biliary cholangitis

Hepatology Research, Volume 55, Issue 8, Page 1128-1138, August 2025.
Abstract Background and aims Sjögren's syndrome is a common comorbidity in patients with primary biliary cholangitis (PBC). Anti‐Ro52 autoantibodies against the protein TRIM21 are often seen in Sjögren's syndrome. TRIM21 consists of four domains (PRY/SPRY, Coiled‐Coil, B‐box, and RING domain), each with a specific function.
Marie Louise Næstholt Dahl, Trine‐Line Korsholm, Jakob Hauge Mikkelsen, Malene Hvid, Ayad Babaee, Matias Hauge Böttcher, Jesper Bach Hansen, Peter Holland‐Fischer, Christian Brix Folsted Andersen, Henning Grønbæk, Bent Deleuran   +10 more
wiley   +1 more source

Association of Long‐Term Conditions and Multimorbidity With Frailty and Sarcopenia: Evidence From the UK Biobank

JCSM Communications, Volume 8, Issue 2, July/December 2025.
ABSTRACT Background Frailty and sarcopenia are common conditions among older adults and may also be highly prevalent among adults with long‐term conditions (LTCs). This study investigates associations between individual LTCs and multimorbidity with the prevalence of frailty and sarcopenia in a large community‐based adult cohort.
Marion Guerrero‐Wyss, Carla Villagran, Sofía Gálvez‐Tejeda, Ana Hernández‐Peregrina, Stuart Johnston, Bhautesh D. Jani, Frederick K. Ho, Stuart R. Gray, Carlos A. Celis‐Morales   +8 more
wiley   +1 more source

Myxedema Coma Patient in Emergency Department: A Case Report.

Journal of Acute Medicine, 2017
Ko-Wen Han, Chih‐Chuan Lin, Chih-Yu Chen, Hsiao-Yun Chao, Cheng-Yu Chien, Hsien‐Yi Chen   +5 more
openalex   +3 more sources

Determining Treatment Dosage for Hypothyroidism Using Machine Learning

Computational Intelligence, Volume 41, Issue 3, June 2025.
ABSTRACT Hypothyroidism is a prevalent chronic condition requiring precise levothyroxine dosing to prevent complications. However, factors such as stress and weight fluctuations complicate dosage determination. This study applies machine learning to improve dosage prediction accuracy.
Christina Zammit, Edward R. Sykes
wiley   +1 more source

Myxedema coma

Medicine, 2017
Raionale: Myxedema coma (MC) is extremely rare but lethal in pediatric patients with hypothyroidism leading to altered mental status and hypothermia. But there is no clinical guideline for such cases. Patient concerns: A 6-year-old Chinese girl presented
Yueniu Zhu, W. Qiu, Mengyan Deng, Xiaodong Zhu   +3 more
semanticscholar   +1 more source

Effectiveness of Paroxetine Versus Non‐Paroxetine Selective Serotonin Reuptake Inhibitors on Mortality and Heart Failure Following Myocardial Infarction: An Active Comparator Population‐Based Cohort Study

Pharmacoepidemiology and Drug Safety, Volume 34, Issue 4, April 2025.
ABSTRACT Background Animal studies suggest that paroxetine, unlike other selective serotonin reuptake inhibitors (SSRIs), may attenuate post‐myocardial infarction (MI) heart failure. We examine the effectiveness of paroxetine versus non‐paroxetine SSRIs on the risk of post‐MI mortality and heart failure in a clinical setting.
Thomas Ravn Lassen, Péter Szentkúti, Henrik Toft Sørensen, Hans Erik Bøtker, Jens Sundbøll   +4 more
wiley   +1 more source

Supplementing risk adjustment with high‐risk pooling using historical data for identifying the high risks

Journal of Risk and Insurance, Volume 92, Issue 1, Page 166-202, March 2025.
Abstract Many regulated health insurance markets with community‐rated premiums rely on risk adjustment (RA) to mitigate insurer‐incentives to risk select. However, insurers remain typically undercompensated for chronically ill enrollees. We use historical data on health spending and risk adjuster information to identify individuals undercompensated by ...
Michel Oskam, Richard C. van Kleef, René C. J. A. van Vliet   +2 more
wiley   +1 more source

Severe myxedema coma and pericardial effusion in a child with Down syndrome: the importance of adherence to levothyroxine therapy

The Turkish Journal of Pediatrics
Background. Myxedema coma is a rare, but life-threatening endocrinological emergency. Myxedema is characterized by altered mental status, and is accompanied by hypotension, bradycardia, hypothermia, bradypnea, hyporeflexia, hyponatremia, and ...
Hatice Feray Arı, Ahmet Anık, Şule Demir, Serkan Fazlı Çelik   +3 more
doaj   +1 more source

Routine Treatment-Resistant Clostridium difficile Infection during Recovery from Myxedema

Case Reports in Gastroenterology, 2017
Development of the extreme form of hypothyroidism defined as myxedema is very rare. Acute symptoms and their management have been described in detail previously. However, not much attention has been devoted to therapeutic challenges that are faced in the
Jan K. Adamski, Björn B. Jäschke, Raija S. Uusitalo-Seppälä, Kalle V.J. Moilanen, Antti V. Pehkonen, Wojciech Weigl   +5 more
doaj   +1 more source