Results 51 to 60 of about 2,226 (194)

A Case of Myxedema Coma and Adrenal Insufficiency Post Pembrolizumab. [PDF]

Case Rep Endocrinol
Background. Despite their important clinical benefits, immune checkpoint inhibitors (ICIs) are associated with a spectrum of side effects known as immune‐related adverse events (irAEs). These can be of various organ system backgrounds, including dermatologic, pulmonary, gastrointestinal, and endocrine.
El Alam A, Fleifel M, El Masri D, Nassani BM, Abou Chaaya J, Minkailou M, Barbat M, Monier A.   +7 more
europepmc   +2 more sources

An autopsy case report of a patient with myxedema coma

Egyptian Journal of Forensic Sciences
Background Myxedema coma, a life-threatening complication of severe hypothyroidism, is associated with high mortality. Detailed autopsy findings from multiple organs in myxedema coma are rarely reported.
Syuichi Tetsuka, Chisa Ashida, Shoichiro Ueno, Ryuta Nakamura, Mio Nihei, Tomoko Ogawa, Yoshimasa Nakazato   +6 more
doaj   +1 more source

Acute collapse in a dog with multiple autoimmune syndromes and polymyositis complicated by suspected organophosphate/carbamate toxicity

Veterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract A 6.5‐year‐old, spayed, female dog presented in acute respiratory distress. On admission, the dog exhibited dyspnoea, bradycardia, cyanosis and gastrointestinal signs, requiring immediate intubation and mechanical ventilation. Diagnostic evaluation revealed reduced butyrylcholinesterase activity, non‐cardiogenic pulmonary oedema, elevated ...
Sarah Hefer, Efrat Kelmer, Michal Mazaki Tovi, Dana Peery, Kobi Aharoni, Nir Edry, Sigal Klainbart   +6 more
wiley   +1 more source

Syndrome of Inappropriate Secretion of Antidiuretic Hormone in a Dog With Meningoencephalitis of Unknown Etiology

Veterinary Medicine and Science, Volume 12, Issue 1, January 2026.
This report describes a case of syndrome of inappropriate antidiuretic hormone secretion (SIADH) in a Maltese with meningoencephalitis of unknown etiology (MUE). The dog was treated with water restriction and tolvaptan, a vasopressin receptor antagonist, which resulted in an improvement in hyponatremia.
Yelim Lee, Jooyoung Park, Yeon Chae, Taesik Yun, Hakhyun Kim, Byeong‐Teck Kang   +5 more
wiley   +1 more source

Rescue Mastectomy in a Patient With Locally Advanced Triple‐Negative Breast Cancer and Severe Biochemical Hypothyroidism: A Multidisciplinary Ethical and Surgical Dilemma

Case Reports in Oncological Medicine, Volume 2026, Issue 1, 2026.
Severe hypothyroidism is traditionally considered a contraindication to elective major surgery due to the risk of perioperative metabolic decompensation and myxedema coma. However, in oncologic settings, delaying surgery may result in irreversible loss of resectability and adverse outcomes.
Nelson Buelvas, Harleen Khatra
wiley   +1 more source

Legions of Presentations of Myxedema Coma

Journal of the ASEAN Federation of Endocrine Societies, 2020
Myxedema coma is associated with decreased mental status and hyponatremia among patients with diagnosed or undiagnosed hypothyroidism. The diagnosis is challenging in the absence of universally accepted diagnostic criteria, but should be considered as a
Nirmalya Roy, Anirban Majumder, Debmalya Sanyal, Soumyabrata Roy Chaudhuri, Suman Sarkar, Ankan Pathak   +5 more
doaj   +1 more source

Determinants of Antimicrobial Resistance in Acinetobacter baumannii Isolates From Intensive Care Patients in Latvia

International Journal of Microbiology, Volume 2026, Issue 1, 2026.
Background Acinetobacter baumannii is a leading nosocomial pathogen in intensive care units (ICUs), often resistant to multiple antibiotics. Data from the Baltic region remain scarce, limiting infection control and stewardship strategies. Methods We conducted an integrated phenotypic–genotypic analysis of A.
Mihails Dolgusevs, Nityanand Jain, Oksana Savicka, Reinis Vangravs, Jevgenijs Bodrenko, Liene Ostele-Cešķe, Gustavs Rindžs, Dace Zemite, Aigars Reinis, Baiba Rozentale, Divakar Sharma   +10 more
wiley   +1 more source

Evolving Real‐World Data and Evidence Use for New Drugs and Regenerative Medical Products Approvals in Japan—An Analysis of the 6‐Year Trend

Clinical Pharmacology &Therapeutics, Volume 118, Issue 6, Page 1405-1421, December 2025.
Several regulatory initiatives have been made to clarify the acceptability and requirements of real‐world data and real‐world evidence (RWD/E) for the benefit/risk assessment of new medical products in Japan. The objectives of this review were to characterize the use of RWD/E in regulatory applications of new medical products and to describe the ...
Suguru Okami, Kako Shimotsumagari, Yasunari Sadatsuki   +2 more
wiley   +1 more source

Management of Primary Adrenal Insufficiency and Overt Hypothyroidism in an HIV‐Positive Patient in a Resource‐Limited Setting: A Case Report

Clinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT In resource‐limited settings, clinicians must maintain a high index of suspicion for primary adrenal insufficiency and hypothyroidism in HIV‐positive patients presenting with non‐specific symptoms. Relying on clinical judgment and response to treatment is crucial when confirmatory tests are unavailable.
Majani Edward, Witness John, Dominick M. Raphael   +2 more
wiley   +1 more source

Sclerosing diseases of the skin

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 23, Issue 10, Page 1282-1301, October 2025.
Summary Sclerosing skin diseases comprise a group of distinct dermatological conditions characterized by fibrotic changes that may severely impair patients’ quality of life. These conditions often present with cutaneous manifestations and, in some cases, may extend to extracutaneous tissues, potentially resulting in significant morbidity and mortality.
Yasamin Kalantari, Katharina Meier, Kamran Ghoreschi, Maria Kinberger, Farzan Solimani   +4 more
wiley   +1 more source