Results 61 to 70 of about 54,493 (178)

Amiodarone induced myxedema coma presenting with cardiogenic shock and junctional rhythm [PDF]

, 2023
We describe the case of an elderly female, with no prior history of thyroid dysfunction, who presented with facial swelling and worsening fatigue. She was found to have myxedema coma, with thyroid-stimulating hormone (TSH) 98.90 uIU/mL and free thyroxine
Nazanin Sheikhan, Sean Darmal, George Trad, Blerina Asllanaj   +3 more
core   +1 more source

Rescue Mastectomy in a Patient With Locally Advanced Triple‐Negative Breast Cancer and Severe Biochemical Hypothyroidism: A Multidisciplinary Ethical and Surgical Dilemma

Case Reports in Oncological Medicine, Volume 2026, Issue 1, 2026.
Severe hypothyroidism is traditionally considered a contraindication to elective major surgery due to the risk of perioperative metabolic decompensation and myxedema coma. However, in oncologic settings, delaying surgery may result in irreversible loss of resectability and adverse outcomes.
Nelson Buelvas, Harleen Khatra
wiley   +1 more source

Determinants of Antimicrobial Resistance in Acinetobacter baumannii Isolates From Intensive Care Patients in Latvia

International Journal of Microbiology, Volume 2026, Issue 1, 2026.
Background Acinetobacter baumannii is a leading nosocomial pathogen in intensive care units (ICUs), often resistant to multiple antibiotics. Data from the Baltic region remain scarce, limiting infection control and stewardship strategies. Methods We conducted an integrated phenotypic–genotypic analysis of A.
Mihails Dolgusevs, Nityanand Jain, Oksana Savicka, Reinis Vangravs, Jevgenijs Bodrenko, Liene Ostele-Cešķe, Gustavs Rindžs, Dace Zemite, Aigars Reinis, Baiba Rozentale, Divakar Sharma   +10 more
wiley   +1 more source

Severe myxedema coma and pericardial effusion in a child with Down syndrome: the importance of adherence to levothyroxine therapy

The Turkish Journal of Pediatrics
Background. Myxedema coma is a rare, but life-threatening endocrinological emergency. Myxedema is characterized by altered mental status, and is accompanied by hypotension, bradycardia, hypothermia, bradypnea, hyporeflexia, hyponatremia, and ...
Hatice Feray Arı, Ahmet Anık, Şule Demir, Serkan Fazlı Çelik   +3 more
doaj   +1 more source

Evolving Real‐World Data and Evidence Use for New Drugs and Regenerative Medical Products Approvals in Japan—An Analysis of the 6‐Year Trend

Clinical Pharmacology &Therapeutics, Volume 118, Issue 6, Page 1405-1421, December 2025.
Several regulatory initiatives have been made to clarify the acceptability and requirements of real‐world data and real‐world evidence (RWD/E) for the benefit/risk assessment of new medical products in Japan. The objectives of this review were to characterize the use of RWD/E in regulatory applications of new medical products and to describe the ...
Suguru Okami, Kako Shimotsumagari, Yasunari Sadatsuki   +2 more
wiley   +1 more source

Management of Primary Adrenal Insufficiency and Overt Hypothyroidism in an HIV‐Positive Patient in a Resource‐Limited Setting: A Case Report

Clinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT In resource‐limited settings, clinicians must maintain a high index of suspicion for primary adrenal insufficiency and hypothyroidism in HIV‐positive patients presenting with non‐specific symptoms. Relying on clinical judgment and response to treatment is crucial when confirmatory tests are unavailable.
Majani Edward, Witness John, Dominick M. Raphael   +2 more
wiley   +1 more source

Myxedema Coma: The Prognosis is Improving

, 1993
Insights into the physiology of thyroid hormone deficiency and the elucidation of thyroid hormone action at the cellular and molecular level have improved our understanding of the pathophysiology of myxedema coma.
Jordan, Richard M.
core   +1 more source

Table_1_Case Report: Myxedema Coma Caused by Immunoglobulin A Vasculitis in a Patient With Severe Hypothyroidism.pdf

, 2022
Myxedema coma is a critical disorder with high mortality rates. Disruption of the compensatory mechanism for severe and long-term hypothyroidism by various causes leads to critical conditions, including hypothermia, respiratory failure, circulatory ...
Nao Hasuzawa (6896738), Kenji Ashida (6189629), Masatoshi Nomura (29095), Sumika Hayashi (11670028), Kouichiro Mizuochi (11670025), Shimpei Iwata (3716260), Tomoki Sako (11670022), Ayako Nagayama (6896725), Tomoyuki Akashi (11670031), Masaharu Kabashima (12104861), Satoko Yoshinobu (10898937), Kenzo Fukuda (11670019), Hiroshi Ito (297745)   +12 more
core   +1 more source

Sclerosing diseases of the skin

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 23, Issue 10, Page 1282-1301, October 2025.
Summary Sclerosing skin diseases comprise a group of distinct dermatological conditions characterized by fibrotic changes that may severely impair patients’ quality of life. These conditions often present with cutaneous manifestations and, in some cases, may extend to extracutaneous tissues, potentially resulting in significant morbidity and mortality.
Yasamin Kalantari, Katharina Meier, Kamran Ghoreschi, Maria Kinberger, Farzan Solimani   +4 more
wiley   +1 more source

Breathing and balance: Clinical insights and management strategies of respiratory acid‐base disorders

Nutrition in Clinical Practice, Volume 40, Issue 4, Page 774-792, August 2025.
Abstract Respiratory acidosis and alkalosis are two of the four main acid‐base processes encountered in clinical practice. These two processes are tightly balanced by breathing. Identification and management of respiratory acid‐base disorders are important for clinicians, particularly when caring for patients with underlying pulmonary and neurological ...
Anne M. Tucker, Tami N. Johnson
wiley   +1 more source