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Synthesis of myxobacteria metabolites
Pure and Applied Chemistry, 2012Myxobacteria are an excellent source of novel secondary metabolites with a range of biological activities. This review details the synthesis of several examples of these natural products. The total synthesis of all the members of the crocacin family is presented where the stereochemistry of the stereotetrad was set via a tin-mediated syn-aldol reaction
Stephen L. Birkett +3 more
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Control of Morphogenesis in Myxobacteria
CRC Critical Reviews in Microbiology, 1987The myxobacteria are Gram-negative soil bacteria that live in large communities known as swarms. The most remarkable characteristic of myxobacteria is their ability to form fruiting bodies that have a species-specific shape and color. Fruiting body formation requires the concerted effort of hundreds of thousands of cells.
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Biologically active secondary metabolites from myxobacteria
Biotechnology Advances, 1993New chemical structures with proven biological activity still are badly needed for a host of applications and are intensively screened for. Suitable compounds may be used as such, or in the form of their derivatives or, equally important, may serve as lead compounds for designing synthetic analogs.
H, Reichenbach, G, Höfle
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Development of the myxobacteria
1965The myxobacteria possess singular characteristics of vegetative growth, cellular morphology, and communal fructification which set them apart as a unique and distinctive order, the Myxobacteriales, within the class Schizomycetes.
Mildred S. Quinlan, Kenneth B. Raper
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CELLULOSE DECOMPOSING MYXOBACTERIA
2023200 strains belonging to the order Myxobacterales were isolated from farm yard manure, compost, liquid manure and soil. These strains were tested for their ability to utilize cellulose. Most of the strains decomposed the cellulose. Myxobacteria decomposed 9-82 per cent of cellulose. They are mesophilic aerobic microorganisms.
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Symbiosis between Myxobacteria and Nitrifying Bacteria
Nature, 1946IN studying the biology of myxobacteria I have arrived at the conclusion that this group of micro-organisms is much more widely spread in Nature than it is commonly considered. The morphology and systematics of myxobacteria are little known to the wider circle of microbiologists, and their role in the circulation of substances in Nature has not been ...
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Lingering Puzzles about Myxobacteria
Microbe Magazine, 2007The myxobacteria are social and capable of constructing intricate macroscopic structures called fruiting bodies. First recognized as bacteria in 1892 by the cryptogamic botanist Roland Thaxter, these exotic anomalies have proved challenging to microbiologists.
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Secondary Metabolism in Myxobacteria
2014In the past 30 years myxobacteria have been established as proficient producers of various secondary metabolites and are regarded today as one of the few important sources for microbial natural products besides actinomycetes and fungi. Epothilone from Sorangium cellulosum recently successfully finished phase III clinical trials as an anticancer agent ...
Helge B. Bode, Rolf Müller
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1984
Myxobacteria offer the opportunity to investigate the multicellular state. For many years myxobacteria were mistaken for fungi because their fruiting bodies have a quite complex morphology (Thaxter 1892). Like other bacteria, myxobacteria can grow and divide as independent cells; they also behave as a primitive multicellular organism in which cells ...
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Myxobacteria offer the opportunity to investigate the multicellular state. For many years myxobacteria were mistaken for fungi because their fruiting bodies have a quite complex morphology (Thaxter 1892). Like other bacteria, myxobacteria can grow and divide as independent cells; they also behave as a primitive multicellular organism in which cells ...
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Social Adaptations in Myxobacteria
1984Myxobacteria are unique amongst the procaryotes in displaying a wide range of social adaptations (Kaiser et al. 1979). They live in compact masses, grow better on polymeric substrates when in dense populations (Rosenberg et al. 1977), and collaborate in producing fruiting bodies.
Amotz Zahavi, Dina Ralt
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