Results 51 to 60 of about 3,994 (155)
ABSTRACT Waterborne diseases and antimicrobial resistance (AMR) pose mounting public health threats across sub‐Saharan Africa, particularly in rapidly urbanising regions dependent on untreated or poorly treated surface waters. This study applied shotgun metagenomic sequencing to characterise microbial communities, virulence factors and antibiotic ...
Oleg N. Reva +8 more
wiley +1 more source
Tumor Cell Migration May Be an Inherent “Foraging” Behavior
Tumor cells gradually form pseudopodia, migrate to necrotic cells, make contact with them, and absorb necrotic cell debris. During this migration, small vesicles formed by dying tumor cells also gradually migrate toward living tumor cells. Once the nutrients from the necrotic cells have been completely absorbed, the living tumor cells will leave ...
Fuqian Zhao +4 more
wiley +1 more source
Prokaryotic PfaB is a terminal acyltransferase that determines the final PUFA product
Abstract Omega‐3 polyunsaturated fatty acids (PUFAs) are essential for human health due to their numerous beneficial biological properties. These compounds are synthesized in marine bacteria and eukaryotic microalgae by PUFA megasynthases (Pfas), which are evolutionarily related to fatty acid synthases (FAS) and polyketide synthases (PKS). In FAS, PKS,
Nahuel Lofeudo +5 more
wiley +1 more source
Are Myxobacteria intelligent? [PDF]
"Intelligence" is understood in different ways. Because humans are proud of their ability to speak, intelligence often includes the ability to communicate with others, to plan for the future, and to solve frequently encountered problems. Myxobacteria are among the most socially adept and ubiquitous of bacteria that live in the soil.
openaire +3 more sources
ABSTRACT Recirculating aquaculture system (RAS) is a promising strategy for economically and environmentally sustainable fish farming. Unfortunately, microorganisms in an RAS may produce off‐flavours that accumulate in fish flesh and reduce consumer attraction for aquaculture‐produced fish. Traditionally, geosmin (GSM) and 2‐methylisoborneol (MIB), the
Petra Camilla Lindholm‐Lehto
wiley +1 more source
We demonstrate that bacterial outer membrane vesicles (OMVs) can enhance antibiotic delivery into Gram‐negative bacteria by bypassing porin‐dependent uptake. Encapsulation of imipenem in OMVs significantly increased its effectiveness against multidrug‐resistant clinical isolates, highlighting OMVs as a promising platform for overcoming permeability ...
Meishan Wu +3 more
wiley +1 more source
Homoterpene Biosynthesis in Fungi
The first homoterpene biosynthetic pathway in the fungal kingdom is reported. A methyltransferase–terpene cyclase pair produces a unique heptamethyl bicyclo[3.3.1]nonane homoterpene via presodorifen, demonstrating that homoterpene biosynthesis via the addition of a C1 unit to terpene diphosphate precursors prior to scaffold formation extends beyond the
Lin Zhou +5 more
wiley +1 more source
Abstract Geosmin (GSM) and 2‐methylisoborneol (MIB) cause objectionable off‐flavors in fish produced in recirculating aquaculture systems (RAS). Remediation solutions have not been developed; therefore, a study was conducted to determine if microbial maturity limits off‐flavor production. Triplicate RAS with newly established nitrification (“immature”)
John Davidson +6 more
wiley +1 more source
Abstract Cyclodepsipeptides (CDPs) represent a huge family of chemically and structurally diverse molecules with a wide ability for molecular interactions. CDPs are cyclic peptide‐related natural products made up of both proteinogenic and nonproteinogenic amino acids linked by amide and ester bonds.
Sophie Liuu +10 more
wiley +1 more source
Stereoselective Syntheses of Cyclic Microsclerodermin Derivatives
Six different cyclic microsclerodermin derivatives are obtained from l‐xylose and d‐arabinose via stereoselective Sakurai allylations and photochemical Arndt‐Eistert homologations. Abstract Starting from l‐xylose and d‐arabinose, six different cyclic microscleroderma derivatives were successfully obtained.
Kevin Bauer, Uli Kazmaier
wiley +1 more source

