Results 41 to 50 of about 417,344 (199)
Advanced Science, EarlyView.ABSTRACT While targeted therapies have improved outcomes in lung adenocarcinoma (LUAD), many patients still lack targetable mutations. Here, we identified alpha‐L‐fucosidase 2 (FUCA2) as a crucial driver of LUAD by preventing cellular senescence. Mechanistically, through the restriction of fucosyltransferase 3 (FUT3)‐mediated α‐1,3‐fucosylation of ...
Lu Chen +18 more
wiley +1 more source
Factores de riesgo de discapacidad moderada a grave por migraña.
Multimed, 2017 RESUMEN Introducción: la migraña es la séptima causa de discapacidad laboral, doméstica y social en el mundo y es la principal causa de discapacidad entre las afecciones neurológicas.
Andrés José Quesada Vázquez +2 more
doaj
Nursing diagnosis “nausea” during chemotherapy: concept analysis
Revista Eletrônica de Enfermagem, 2017 A study with the objective to analyze the concept nausea in chemotherapeutic treatment, to improve the nursing diagnosis “nausea”. We used the model proposed by Walker and Avant as a theoretical reference and, we conducted an integrative review in the ...
Aline Maria Bonini Moysés +3 more
doaj +1 more source
Advanced Science, EarlyView.A nebulized nanoassembly alleviates radiation‐induced lung injury by reprogramming macrophages through coordinated ROS scavenging, NAD+ replenishment, and PPAR‐γ activation. Redox balance, mitochondrial homeostasis, and immune regulation are restored, revealing a microenvironment‐centered strategy for localized radioprotection.
Mingquan Gao +11 more
wiley +1 more source
Nausea: a review of pathophysiology and therapeutics
Therapeutic Advances in Gastroenterology, 2016 The sensation of nausea is a common occurrence with diverse causes and a significant disease burden. Nausea is considered to function as a protective mechanism, warning the organism to avoid potential toxic ingestion. Less adaptive circumstances are also
Prashant Singh +2 more
doaj +1 more source
Frontiers in Pharmacology, 2019 ObjectiveThe expectation of developing side effects can enhance the likelihood to develop them – a phenomenon referred to as nocebo effect. Whether nocebo effects can be reduced by lowering negative expectancies, is not clear. The aim of this prospective
Karin Meissner +11 more
doaj +1 more source
Advanced Science, EarlyView.A novel exercise‐inducible myokine acidic ribosomal protein P2 (RPLP2), initially identified from human trials, is presented here, whose circulating levels negatively correlate with clinical anxiety severity. Muscle‐derived RPLP2 enhances hippocampal ribosomal assembly and adult neurogenesis to rescue stress‐induced anxiety deficits.
Peiyu Luo +18 more
wiley +1 more source
Advanced Science, EarlyView.We constructed a brain‐targeted AFn‐DPZ nanodrug delivery system and identified EphB1 as its receptor on the blood‐brain barrier (BBB). This system facilitates drug transport across the BBB and thereby ameliorates cognitive impairment in Alzheimer's disease.
Shilin Wen +5 more
wiley +1 more source
O efeito do jazz em A Náusea de Jean-Paul Sartre
Artefilosofia, 2017 O objetivo deste estudo é analisar e discutir o papel que a música exerce no romance A náusea de Jean-Paul Sartre. Assim, em um primeiro momento se irá descrever o modo como a contingência se apresenta na obra, para em um segundo momento explicitar o ...
Artur Ricardo de Aguiar Weidmann
doaj
Consumed by Abdominal Distention
Arthritis Care &Research, EarlyView.
Abimbola Fadairo‐Azinge +3 more
wiley +1 more source