Results 71 to 80 of about 585,553 (296)

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Nausea: a review of pathophysiology and therapeutics

Therapeutic Advances in Gastroenterology, 2016
The sensation of nausea is a common occurrence with diverse causes and a significant disease burden. Nausea is considered to function as a protective mechanism, warning the organism to avoid potential toxic ingestion. Less adaptive circumstances are also
Prashant Singh, Sonia S. Yoon, Braden Kuo   +2 more
doaj   +1 more source

Individual Factors Contributing to Nausea in First-Time Chemotherapy Patients: A Prospective Cohort Study

Frontiers in Pharmacology, 2019
ObjectiveThe expectation of developing side effects can enhance the likelihood to develop them – a phenomenon referred to as nocebo effect. Whether nocebo effects can be reduced by lowering negative expectancies, is not clear. The aim of this prospective
Karin Meissner, Karin Meissner, Nicola Talsky, Elisabeth Olliges, Elisabeth Olliges, Carmen Jacob, Carmen Jacob, Carmen Jacob, Oliver J. Stötzer, Christoph Salat, Michael Braun, Raluca Flondor   +11 more
doaj   +1 more source

DNA Nanoflower LYTACs Enable Efficient VEGF Degradation and Verteporfin Loading for Combined Therapy of Wet Age‐Related Macular Degeneration

Advanced Science, EarlyView.
An integrated approach that combines a DNA nanoflower VEGF degrader with photodynamic therapy is developed for the treatment of wet age‐related macular degeneration, which reduces the risk of VEGF reactivation‐induced CNV recurrence and minimizes the systemic side effects associated with photodynamic therapy.
Mengxuan Li, Yan Yue, Sijin Wu, Xinyu He, Jiayi Song, Shuwen Ma, Haokun Zhang, Chenyu Xu, Song Chen, Yanming Huang, Songbo Xie, Hua Yan   +11 more
wiley   +1 more source

PLANEACIÓN DIDÁCTICA GENERAL DE LA ASIGNATURA: FILOSOFÍA CONTEMPORÁNEA [PDF]

, 2018
GUÍA DIDÁCTICA / PLANEACIÓN DIDÁCTICA ...
ARRAZOLA VEGA MITZI NAZARETH, DIAZ SILVA ALBERT, REYES RODRIGUEZ MARIA DEL ROSARIO, REYES RODRIGUEZ MARIA DEL ROSARIO   +3 more
core   +1 more source

Machine Learning for Green Solvents: Assessment, Selection and Substitution

Advanced Science, EarlyView.
Environmental regulations have intensified demand for green solvents, but discovery is limited by Solvent Selection Guides (SSGs) that quantify solvent sustainability. Training a machine learning model on GlaxoSmithKline SSG, a database of sustainability metrics for 10,189 solvents, GreenSolventDB is developed. Integrated with Hansen solubility metrics,
Rohan Datta, Janhavi Nistane, Abhishek Sose, Harikrishna Sahu, Rampi Ramprasad   +4 more
wiley   +1 more source

O efeito do jazz em A Náusea de Jean-Paul Sartre

Artefilosofia, 2017
O objetivo deste estudo é analisar e discutir o papel que a música exerce no romance A náusea de Jean-Paul Sartre. Assim, em um primeiro momento se irá descrever o modo como a contingência se apresenta na obra, para em um segundo momento explicitar o ...
Artur Ricardo de Aguiar Weidmann
doaj  

Noninvasive Quantification of Nausea Severity in Pediatric Functional Nausea

Gastro Hep Advances
Background and Aims: Functional nausea is an idiopathic gastrointestinal disorder that is common in children, carries a substantial health-care cost, and lacks objective diagnostic testing, relying primarily on symptomatology with an otherwise normal ...
Nicole D. Muszynski, Suseela Somarajan, Jordan D. Busing, Alexandra C. Russell, Sari A. Acra, Leonard A. Bradshaw   +5 more
doaj   +1 more source

Influência da reposição volêmica perioperatória sobre náuseas e vômitos no pós-operatório. [PDF]

, 2008
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina.
Paganelli, Andre Luis Momm
core  

The Effect of a Standardized Ginger Extract on Chemotherapy-Induced Nausea-Related Quality of Life in Patients Undergoing Moderately or Highly Emetogenic Chemotherapy: A Double Blind, Randomized, Placebo Controlled Trial

Nutrients, 2017
Ginger supplementation could be an effective adjuvant treatment for chemotherapy-induced nausea (CIN). The aim of this clinical trial was to address significant methodological limitations in previous trials.
W. Marx, A. McCarthy, K. Ried, D. McKavanagh, L. Vitetta, A. Sali, A. Lohning, E. Isenring   +7 more
semanticscholar   +1 more source