ABSTRACT Prostate cancer (PCa) is the second most frequently diagnosed malignancy among men and the sixth leading cause of cancer‐related mortality worldwide. Radical prostatectomy remains the standard treatment for localized disease; however, approximately one‐third of patients develop biochemical recurrence within 10 years. Although prostate‐specific
Juliana Ramos Chaves +7 more
wiley +1 more source
Monocyte-derived IL-1β predicts and promotes HBsAg decline in chronic hepatitis B patients under nucleoside analogue therapy. [PDF]
Shigeno S +15 more
europepmc +1 more source
Núcleos de Aprendizaje Prioritarios
La Asamblea del CFE, 26 resuelve: Aprobar para la discusión, conforme el art. 10 de la RCFE Nº 1/07, los Núcleos de Aprendizaje Prioritarios para el segundo ciclo de la educación primaria y el séptimo año de educación primaria/primer año de educación ...
DE CARA Secretario, SILEONI Ministro
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Researcher highlight: Extending beyond the recently reported compound heterozygous case, we report the same TYMP c.131G>C variant in a homozygous configuration, delivering key genetic evidence for its standalone pathogenicity in MNGIE. ABSTRACT Background Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is an autosomal recessive disorder ...
Ling Li +6 more
wiley +1 more source
From HBV to MASLD Cirrhosis: Mechanistic Insights and Therapeutic Strategies
This review examines the epidemiological shift from hepatitis B virus (HBV) to metabolic dysfunction‐associated steatotic liver disease (MASLD) as the leading cause of cirrhosis globally. It highlights the distinct pathogenic mechanisms between HBV and MASLD cirrhosis and discusses evolving diagnostic tools and therapeutic strategies tailored to the ...
Hanqi Yu +5 more
wiley +1 more source
The Safety of Interferon‐Based Therapies in Chronic Hepatitis B Patients With Compensatory Cirrhosis
While nucleos(t)ide analog (Nuc) therapy is the standard for chronic hepatitis B, pegylated interferon‐alpha (Peg‐IFN‐α) provides unique advantages, including finite treatment duration and long‐term benefits. However, its use in patients with compensated cirrhosis remains limited due to persistent safety concerns about potential decompensation and ...
Qiran Zhang +32 more
wiley +1 more source
Development of a Coaxial Over‐the‐Scope Bimanual Robot Enabling Lesion‐Aligned Manipulation for ESD
ABSTRACT Background Endoscopic Submucosal Dissection (ESD) requires high expertise as conventional endoscopes cannot provide simultaneous traction and dissection, resulting in unstable visualisation and inconsistent cutting depth. Methods A coaxial over‐the‐scope bimanual robotic system was developed to enable lesion‐aligned traction and dissection ...
Chanwoo Kim +8 more
wiley +1 more source
Analysis of Viral Blips Through Week 192 of the DRIVE-FORWARD and DRIVE-AHEAD Phase 3 Studies of Doravirine-Based Regimens in Adults Living With Previously Untreated HIV-1. [PDF]
Molina JM +7 more
europepmc +1 more source
Ecological Niche Divergence in an Invasive Non‐Native Shrub: Implications for Risk Assessments
The worldwide spread invasive shrub Nicotiana glauca (tree tobacco) underwent divergent niche shifts across two of its invaded regions. In the mediterranean region it presents high thermal seasonality and low thermal seasonality in the Caatinga (Brazil).
Fellipe Alves Ozorio do Nascimento +4 more
wiley +1 more source
Estudios experimentales de núcleos en rotación
En esta tesis se presentan varias contribuciones al estudio de la estructura de núcleos en rotación: 1. Estudiamos dos métodos para hacer frente al problema del apilamiento.
Espino Navas, José Manuel
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