Results 161 to 170 of about 48,719 (218)

Increased Risk for Liver Disease in Patients With Chronic Hepatitis B Virus Infection and Low‐Level Viraemia

Alimentary Pharmacology &Therapeutics, Volume 63, Issue 12, Page 1626-1634, June 2026.
We used an administrative claims dataset to evaluate the relationship between hepatitis B virus (HBV) low‐level viraemia and subsequent liver‐related outcomes in patients with chronic HBV. We found that individuals with HBV low‐level viraemia have an increased risk for liver‐related events (i.e., cirrhosis, decompensation, and hepatocellular carcinoma)
Paul Y. Kwo, Laura E. Telep, Lai San Hong, Ching Yi Chuo, Betty Chiang, Sarjita D. Naik, Catherine T. Frenette, Amanda W. Singer, Anand P. Chokkalingam, Robert J. Wong, Leland J. Yee, Camilla S. Graham   +11 more
wiley   +1 more source

Synthesis of Novel d-Glucopyranuronamide-Based Nucleos(t)ide Analogs Bearing (Triazolyl)methyl Phosph(on)ate Motifs With Anticancer and Antibacterial Potential. [PDF]

ChemMedChem
Manuel DM, Moreira T, Filipe SR, Vojáčková V, Jorda R, Xavier NM.   +5 more
europepmc   +1 more source

A 2100‐km jaguar journey redefines mobility and large‐scale conservation priorities during large carnivore dispersal

Ecology, Volume 107, Issue 6, June 2026.
Jon Morant, Esther Sebastián‐González, Leandro Reverberi Tambosi, Alan Eduardo de Barros, Renato A. Moreira, Francesca Belem Lopes Palmeira, Douglas dos Santos Silva, Tiago J. Silveira, Anah T. A. Jácomo, Leandro Silveira   +9 more
wiley   +1 more source

Phosphatase PPP1CC Regulates the First Lineage Segregation by GAS5 in Mouse Preimplantation Embryos

Cell Proliferation, Volume 59, Issue 6, June 2026.
Subcortical GAS5 directs PPP1CC phosphatase spatiotemporal positioning during mouse morula‐blastocyst transition, controlling YAP dephosphorylation to drive first embryonic lineage specification. ABSTRACT The transcriptional effector of the Hippo signalling pathway, YAP, regulates the first lineage specification in mouse preimplantation embryos ...
Jianwu Wang, Yan Zhang, Laijin Wu, Hongshuang Xie, Guang Yang, Yiwei Zhang, Cheng Huang, Shanyi Chou, Xuehan Li, Zhonghua Liu, Jiaqiang Wang   +10 more
wiley   +1 more source

Oral Microbiome Diversity Matters on Nucleos(t)ide Analogue Cessation in Chronic Hepatitis B. [PDF]

J Infect Dis
Ghorbani M, Kvedaraite A, Al-Manei K, Too CB, Cederberg S, Johannessen A, Reikvam DH, Valentini D, Maucourant C, Björkström NK, Aleman S, Sällberg Chen M.   +11 more
europepmc   +1 more source

Bicategorias Internas em Categorias Aditivas com Núcleos

Mestrado em MatemáticaO presente trabalho descreve a noção de bicategoria interna numa categoria aditiva com núcleos. Está dividido em três partes essenciais: A primeira parte estabelece o resultado já conhecido de que a categoria Cat(A) das ...
Ferreira, Nelson Martins
core  

Tacrolimus Concentration/Dose Ratio in Hematopoietic Cell Transplantation Recipients: An Exploratory Study of Metabolizer Phenotyping and Clinical Outcomes

Clinical and Translational Science, Volume 19, Issue 6, June 2026.
ABSTRACT Tacrolimus pharmacokinetics shows wide interindividual variability after allogeneic hematopoietic cell transplantation (HCT), potentially influencing both effectiveness and toxicity. The concentration‐to‐dose (C/D) ratio has been proposed as a simple surrogate marker of tacrolimus metabolism, enabling patient stratification into fast or slow ...
Luiz Carlos da Costa‐Junior, Rita de Cássia Barbosa da Silva Tavares, Marina Izu, Simone Cunha Maradei, Maria Claudia Rodrigues Moreira, Marta Colares Nogueira, Décio Lerner, Teresa de Souza Fernandez, Paulo Caleb Júnior Lima Santos   +8 more
wiley   +1 more source

No Immediate Need for Nucleos(t)ide Analogs Treatment in Untreated Patients With Low-Level Viremia: Evidence From Hepatitis B Virus RNA Levels. [PDF]

Clin Transl Gastroenterol
Zhang Y, Wu J, Gao H, Gao L, Wang L, Li T.   +5 more
europepmc   +1 more source

Plant organelle C‐to‐U RNA editing factors can operate successfully in yeast (Saccharomyces cerevisiae) as an easily amenable eukaryotic system for their functional analysis

The FEBS Journal, Volume 293, Issue 11, Page 3166-3186, June 2026.
Plant‐type pentatricopeptide repeat proteins capable of C‐to‐U RNA editing perform faithfully when expressed in a new heterologous system, the yeast Saccharomyces cerevisiae. They were tested with constitutive and inducible expression and with a set of different solubility tags. PPR56, PPR65, and PPR78 from P.
Shyam Ramanathan, Annika Hanraths, Jingchan Xie, Mareike Schallenberg‐Rüdinger, Volker Knoop   +4 more
wiley   +1 more source

Incidence and Characteristics of HBV Reactivation‐Related Events Following HBsAg Seroclearance: Long‐Term Follow‐up of a Population‐Based Cohort in Japan

Hepatology Research, Volume 56, Issue 6, Page 944-955, June 2026.
In a population‐based cohort in Japan, HBV reactivation‐related events were observed after HBsAg seroclearance, including one virologically confirmed hepatic flare occurring spontaneously without chemotherapy or immunosuppression. These findings indicate that HBsAg seroclearance does not always represent complete viral eradication, supporting the need ...
Kazumi Yamasaki, Satoshi Shirahama, Takahiro Yasaka, Shota Yamaguchi, Masashi Mizokami, Junko Tanaka, Hiroaki Okamoto, Hiroshi Yatsuhashi   +7 more
wiley   +1 more source