Results 131 to 140 of about 684 (202)
Animal Models and Experimental Medicine, EarlyView.Scientific research with animals in the UK is regulated by the Animals (Scientific Procedures) Act 1986 with the National Centre for the Replacement, Refinement and Reduction of Animals in Research providing support for best practice and facilitating development of new approach methodologies.
Ewan St. John Smith +6 more
wiley +1 more source
Synergistische Entwicklungsstrategien von Inhibitoren gegen humane UDP‐Galactose‐4‐Epimerase
Angewandte Chemie, EarlyView.Die Epimerase GalE ist essenziell für die Biosynthese von krebsrelevanten O‐GalNAc Glykanen. Wir verwenden orthogonales, strukturbasiertes Screening niedermolekularer Fragmente an, um kovalente und nichtkovalente Inhibitoren gegen GalE mit nicht mehr als 22 optimierten Verbindungen zu erhalten.
William M. Browne +22 more
wiley +1 more source
Tạp chí Khoa học Đại học Cần ThơNghiên cứu này được thực hiện nhằm xác định các thông số phù hợp, cụ thể là tỷ lệ bổ sung bột nấm rơm và nấm men, trong quy trình sản xuất bánh mì sandwich nấm rơm.
Nguyễn Thị Kiều Diễm +5 more
doaj
Ribozyme für die RNA‐katalysierte Methylierung und Markierung von RNA
Angewandte Chemie, EarlyView.Ribozyme sind vielseitige Werkzeuge für die präzise Modifikation von RNA. Das Reaktionsspektrum in‐vitro‐selektierter Ribozyme reicht vom Einbau funktioneller Gruppen und Fluorophoren bis zu natürlichen RNA‐Methylierungen. Dieser Übersichtsartikel präsentiert Cofaktor‐abhängige Ribozyme für die positionsgenaue Markierung und Modifikation von RNA ...
Carolin P. M. Scheitl +1 more
wiley +1 more source
KHẢO SÁT MỘT SỐ YẾU TỐ ẢNH HƯỞNG ĐẾN QUY TRÌNH CHẾ BIẾN CHÀ BÔNG NẤM RƠM (Volvariella volvacea) [PDF]
This study aimed to determine the appropriate blanching method and drying temperature for the processing of straw mushroom floss. The study included an investigation of the effect of 3 factors: (i) blanching method (hot water, steam); (ii) blanching time
Anh, Nguyen Thi Van +3 more
core +1 more source
Animal Research and One Health, EarlyView.(1) Kbhb modification of FBP1 and PCK1 is involved in regulation of the gluconeogenesis pathway. (2) Kbhb of FBP1 and PCK1 is catalyzed by p300 and removed by HDACs. (3) BHB induced an increase in the enzymatic activity of FBP1 and PCK1 through Kbhb modification at the K43 site of FBP1 and the K191 site of PCK1.
DingPing Feng +6 more
wiley +1 more source
Minimalist Footwear Acutely Alters Running Kinematics in Runners With Medial Tibial Stress Syndrome
Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.Purpose To assess immediate biomechanical changes in runners with medial tibial stress syndrome (MTSS) when transitioning from standard to minimalist running shoes. Methods Active runners diagnosed with MTSS ran on a treadmill at 10 km/h using standard and minimalist running shoes. Hip, knee, and ankle joint kinematics were captured using a 16‐infrared‐
Quyet Thang Nguyen +6 more
wiley +1 more source
Arthritis &Rheumatology, Accepted Article.Objective To identify autoantibodies in presymptomatic individuals that associate with the onset of rheumatoid arthritis (RA), and to distinguish early RA from osteoarthritis (OA), particularly in individuals lacking classic RA serological markers. Methods We analyzed serum and plasma from three cohorts: pre‐symptomatic individuals who later developed ...
Outi Sareila +12 more
wiley +1 more source
Biotechnology and Bioengineering, EarlyView.ABSTRACT Yeast sugar transporters have highly evolved for preferential glucose transport, a significant roadblock for utilizing non‐glucose sugars in renewable feedstocks such as lignocellulosic biomass. To enable simultaneous transport of multiple sugars, native hexose transporters were replaced by SWEET7p from Arabidopsis thaliana in engineered ...
Nurzhan Kuanyshev +6 more
wiley +1 more source
Impact of Process Interruptions in the Production of Lysates for Cell‐Free Expression Systems
Biotechnology and Bioengineering, EarlyView.ABSTRACT Cell‐free gene expression systems offer cell‐like functionalities outside the confines of the cell, garnering increasing interest for applications from biomanufacturing to sensing. As applications expand, the need to implement economically scaled processes to produce cellular lysates grows.
Katherine A. Rhea +11 more
wiley +1 more source