Results 191 to 200 of about 116,528 (325)

Integration of epigenetics into ecotoxicology: insights and fundamental research needs

open access: yesBiological Reviews, EarlyView.
ABSTRACT Epigenetics refers to heritable changes in genome function that occur without direct alterations to the DNA sequence. A multitude of environmental contaminants can influence the epigenetic marks of a genome. Changes of epigenetic marks including DNA methylation, histone modifications, and non‐coding RNAs can induce alterations at the gene ...
Albano Pinto   +3 more
wiley   +1 more source

NF‐κB Is a Potential Therapeutic Target for Histone Deacetylase Inhibitor‐Resistant Cutaneous T‐Cell Lymphoma

open access: yesCancer Science, EarlyView.
We identified a novel mechanism of resistance to histone deacetylase inhibitors (HDACi) in cutaneous T‐cell lymphoma (CTCL), mediated by NF‐κB activation. This finding highlights NF‐κB as a potential therapeutic target for overcoming HDACi resistance in CTCL.
Yuto Takahashi   +10 more
wiley   +1 more source

The N-Acetyltransferase 2 Polymorphism and Susceptibility to Inflammatory Bowel Disease: A Case-Control Study. [PDF]

open access: yesPharmacol Res Perspect
Petryszyn P   +9 more
europepmc   +1 more source

Data from GSK-3β–Regulated N-Acetyltransferase 10 Is Involved in Colorectal Cancer Invasion

open access: gold, 2023
Hong Zhang   +10 more
openalex   +1 more source

KAT2A Deficiency Suppresses Lung Cancer Progression by Downregulating MYC Through Decreasing MYC Succinylation

open access: yesCancer Science, EarlyView.
ABSTRACT Succinylation has been shown to promote lung cancer development, but its mechanism remains incompletely understood. KAT2A, a succinyltransferase, acts as an oncogene in multiple cancers, but its role in mediating lung cancer progression is unclear.
Junping Li   +7 more
wiley   +1 more source

Backbone resonance assignments of dopamine N-acetyltransferase in free and cofactor-bound states. [PDF]

open access: yesBiomol NMR Assign
Wu CY   +8 more
europepmc   +1 more source

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