Characterization of Lysine Acetyltransferase Activity of Recombinant Human ARD1/NAA10
Molecules, 2020 Arrest defective 1 (ARD1), also known as N(alpha)-acetyltransferase 10 (NAA10) was originally identified as an N-terminal acetyltransferase (NAT) that catalyzes the acetylation of N-termini of newly synthesized peptides.
Tam Thuy Lu Vo +11 more
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PLoS ONE, 2011 Heparin acetyl-CoA:alpha-glucosaminide N-acetyltransferase (N-acetyltransferase, EC 2.3.1.78) is an integral lysosomal membrane protein containing 11 transmembrane domains, encoded by the HGSNAT gene.
Xiaolian Fan +4 more
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Enhanced Characterization of Drug Metabolism and the Influence of the Intestinal Microbiome: A Pharmacokinetic, Microbiome, and Untargeted Metabolomics Study. [PDF]
, 2020 Determining factors that contribute to interindividual and intra-individual variability in pharmacokinetics (PKs) and drug metabolism is essential for the optimal use of drugs in humans.
Alhaja, Maher +8 more
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A four-month gatifloxacin-containing regimen for treating tuberculosis. [PDF]
, 2014 BACKGROUND: Shortening the course of treatment for tuberculosis would be a major improvement for case management and disease control. This phase 3 trial assessed the efficacy and safety of a 4-month gatifloxacin-containing regimen for treating rifampin ...
Amukoye, Evans +19 more
core +1 more source
Crystal Structure of the Zorbamycin-Binding Protein ZbmA, the Primary Self-Resistance Element in Streptomyces flavoviridis ATCC21892 [PDF]
, 2015 The bleomycins (BLMs), tallysomycins (TLMs), phleomycin, and zorbamycin (ZBM) are members of the BLM family of glycopeptide-derived antitumor antibiotics.
Babnigg, Gyorgy +12 more
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Progress of Acetyltransferase Gene Naa10 in Cancer
Zhongliu Fangzhi Yanjiu, 2019 N-α-terminal acetyltransferase gene 10 (Naa10) is extensively expressed in eukaryotic cells, and its encoded Naa10p is the catalytic subunit of the NatA complex.
HE Zukun +3 more
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N-acetyltransferase 2 polymorphism in Parkinson's disease. The Rotterdam study [PDF]
, 1999 The N-acetyltransferase-2 gene (NAT-2) has been associated with Parkinson's disease. The genotype associated with slow acetylation has been reported to be increased in patients with Parkinson's disease.
Breteler, M.M.B. (Monique) +5 more
core +3 more sources
Biomolecules, 2021 We examined the effects of two histone acetyltransferase (HAT) inhibitors on the activity of rice serotonin N-acetyltransferases (SNAT). Two rice recombinant SNAT isoenzymes (SNAT1 and SNAT2) were incubated in the presence of either MG149 or MB3, HAT ...
Kyungjin Lee +2 more
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Transcriptomic responses of the olive fruit fly Bactrocera oleae and its symbiont Candidatus Erwinia dacicola to olive feeding [PDF]
, 2017 The olive fruit fly, Bactrocera oleae, is the most destructive pest of olive orchards worldwide. The monophagous larva has the unique capability of feeding on olive mesocarp, coping with high levels of phenolic compounds and utilizing non-hydrolyzed ...
Ben-Yosef, Michael +9 more
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Optimized bisubstrate inhibitors for the actin N-terminal acetyltransferase NAA80
Frontiers in Chemistry, 2023 Acetylation of protein N-termini is one of the most common protein modifications in the eukaryotic cell and is catalyzed by the N-terminal acetyltransferase family of enzymes.
Line M. Myklebust +8 more
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