Results 31 to 40 of about 116,528 (325)
The Use of Plasmapheresis in Treatment of Patients with Infertility, Peritoneal Endometriosis and Nat2 Gene Polymorphism [PDF]
, 2016 It is known that 30–40 % of patients with peritoneal endometriosis suffer from infertility. Half of the patients with endometriosis are identified point mutation in NAT2 – gene, which plays an important role in the acetylation of aromatic and ...
Dubinskaya, E. (Ekaterina) +2 more
core +2 more sources
Frontiers in Pharmacology, 2022 N-acetyltransferase 1 (NAT1) is a xenobiotic metabolizing enzyme that uses acetyl coenzyme A (AcCoA) as a cofactor for N-acetylation of many carcinogens including aromatic amines and alkylanilines. NAT1 is characterized by single nucleotide polymorphisms
Mariam R. Habil +2 more
doaj +1 more source
Mercapturate Pathway in the Tubulocentric Perspective of Diabetic Kidney Disease [PDF]
, 2019 BACKGROUND: The recent growing evidence that the proximal tubule underlies the early pathogenesis of diabetic kidney disease (DKD) is unveiling novel and promising perspectives.
Antunes, A +7 more
core +1 more source
مجله دانشگاه علوم پزشکی گرگان, 2021 Background and Objective: The emergence of drug resistance in Mycobacterium tuberculosis and especially drug resistant strains has created problems for the treatment of tuberculosis control, worldwide.
Elnaz Razzagi, Changiz Ahmadizadeh
doaj
Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene [PDF]
, 2015 Journal ArticleDecreased insulin sensitivity, also referred to as insulin resistance (IR), is a fundamental abnormality in patients with type 2 diabetes and a risk factor for cardiovascular disease. While IR predisposition is heritable, the genetic basis
Alan Sinaiko +48 more
core +1 more source
On the role of residue phosphorylation in 14-3-3 partners: AANAT as a case study [PDF]
, 2017 Twenty years ago, a novel concept in protein structural biology was discovered: the intrinsically disordered regions (IDRs). These regions remain largely unstructured under native conditions and the more are studied, more properties are attributed to ...
Bustos, Diego Martin +2 more
core +2 more sources
Melatonin synthesis in the human pineal gland [PDF]
, 2007 Poster presentation: The mammalian pineal organ is a peripheral oscillator, depending on afferent information from the so-called master clock in the suprachiasmatic nuclei of the hypothalamus.
Ackermann, Katrin +4 more
core +1 more source
Carcinogenic potential of arylamine N-acetyltransferase in Asian populations
Journal of Cancer Research and Practice, 2018 Arylamine N-acetyltransferase (NAT) is a phase II metabolizing enzyme, which belongs to the transferase family; specifically those acyltransferases which transfer various groups except aminoacyl. NATs are found in both prokaryotes and eukaryotes.
Saba Kabir, Abdul Rehman
doaj +1 more source
Role of N-acetyltransferase 2 gene polymorphism in the human pathology
Acta Biomedica Scientifica, 2021 Nowadays multiple heterogeneous chemicals affect the human body. They include drugs, household chemicals, dyes, food supplements and others. The human organism can modify, inactivate, and eliminate the chemicals by biotransformation enzymes.
N. P. Peretolchina +2 more
doaj +1 more source
Cytotoxic and N-Acetyltransferase Inhibitory Meroterpenoids from Ganoderma cochlear
Molecules, 2018 Seven compounds, including two pairs of new meroterpenoids, (+)- and (−)-gancochlearol C (1), (+)- and (−)-cochlearoid Q (3), and a new meroterpenoid gancochlearol D (2), together with four known meroterpenoids were isolated from the aqueous ...
Li-Zhi Cheng +5 more
doaj +1 more source