Results 121 to 130 of about 15,520,995 (329)

Perfect match: Improved cross-modal embeddings for audio-visual synchronisation

, 2018
This paper proposes a new strategy for learning powerful cross-modal embeddings for audio-to-video synchronization. Here, we set up the problem as one of cross-modal retrieval, where the objective is to find the most relevant audio segment given a short ...
Chung, Joon Son, Chung, Soo-Whan, Kang, Hong-Goo   +2 more
core   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

A new coordination tetramer of copper(I) iodide and benzyldimethylamine: tetra-μ3-iodido-tetrakis[(benzyldimethylamine-κN)copper(I)]

Acta Crystallographica Section E, 2009
The title compound, [Cu4I4(C9H13N)4], has a distorted cubane-like [Cu4I4] core structure. Each CuI atom is tetrahedrally coordinated by three I atoms and one N atom of an benzyldimethylamine ligand. Each I atom acts as a μ3-ligand, linking three
Jianguo Pan, Yujie Cui, Yuebao Li, Shuying Yang   +3 more
doaj   +1 more source

Entry point into new trimeric and tetrameric imide-based macrocyclic esters derived from isophthaloyl dichloride and methyl 6-aminonicotinate [PDF]

, 2012
The one-step reaction of isophthaloyl dichloride with the 2-aminopyridine derivative (methyl 6-aminonicotinate) yields (i) a trimer-based macrocycle (EsIO)3 and (ii) a tetramer-based macrocycle (EsIO)4 in modest isolated synthetic yields (total of 25 ...
Gallagher, John F., Mocilac, Pavle
core   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

catena-Poly[[bis(N-ethylethylenediamine-κ2N,N′)copper(II)]-μ-cyanido-κ2N:C-[dicyanido-κ2C-palladium(II)]-μ-cyanido-κ2C:N]

Acta Crystallographica Section E, 2009
The title compound, [CuPd(CN)4(C4H12N2)2]n, consists of one-dimensional chains. The Cu and Pd atoms are both located on centers of symmetry in an alternating array of [Cu(N-Eten)2]2+ (N-Eten = N-ethylethylenediamine) and [Pd(CN)4]2− units.
Takashiro Akitsu, Yuki Endo
doaj   +1 more source

Quasi-({\lambda}; n)-distance-balanced graphs

, 2019
Comment: 15 pages, 13 figures, this paper is prepared to submit to a journal in the ...
Pourhadi, Ehsan, Faghani, Morteza
openaire   +1 more source

Deuteron Structure at Small $N - N$ Distances from Inelastic $e-D$ and $p-D$ Reactions

, 2001
The outline of the presentation is as follows: I. Nucleon Distribution in the Deuteron from $e-D$ and $p-D$ Processes. II. Quark Distribution in Deuteron from its Fragmentation to Pions and Deep Inelastic $e-D$ scattering. III.Difference of These Two Distributions and Its Possible Understanding.
Illarionov, A. Yu., Lykasov, G. I.
openaire   +2 more sources

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source