Results 131 to 140 of about 15,520,995 (329)

Tris(2,2′-bipyridine-κ2N,N′)cobalt(III) octacyanidotungstate(V)

open access: yesActa Crystallographica Section E, 2010
In the title compound, [Co(C10H8N2)3][W(CN)8], the Co atom (..2 site symmetry) is coordinated by six N atoms from three 2,2′-bipyridine ligands in an octahedral geometry; the Co—N bond distances range from 1.926 (2) to 1.939&
Qian Jun, Chi Zhang
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Limiting Distances for Flame Merging of Multiple n-Heptane and Di-tert-Butyl Peroxide Pool Fires

open access: yesChemical Engineering Transactions, 2013
Experiments to determine the limiting distances for flame merging of multiple pool fires are presented. As model substances n-heptane and di-tert-butyl peroxide are used.
S. Schaelike   +3 more
doaj   +1 more source

Density functional theory and DFT+U study of transition metal porphines adsorbed on Au(111) surfaces and effects of applied electric fields

open access: yes, 2006
We apply Density Functional Theory (DFT) and the DFT+U technique to study the adsorption of transition metal porphine molecules on atomistically flat Au(111) surfaces.
Batista, Victor S.   +6 more
core   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

The Modified Superomedial Pedicle Breast Reduction Technique for Cases with SN–N Distance Exceeding 33 cm

open access: yesAesthetic Plastic Surgery
Abstract Background Symptomatic breast hypertrophy affects the quality of life of a large number of women globally. Many reduction mammoplasty techniques have been described for patients with breast hypertrophy. The aim of this study was to provide our clinic’s experience in utilizing the modified superomedial pedicle
Georgina Panopoulou   +3 more
openaire   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Tris(6-tert-butyl-4-methylpyridazine-3-thiolato-κ2N,S)aluminium

open access: yesIUCrData, 2016
The title complex, [Al(C9H13N2S)3], is composed of an aluminium atom coordinated by three bidentate thiopyridazine ligands in an octahedral environment. It has approximate C3 symmetry, with Al—N distances in the range 1.9732 (17)–1.9794 (17) Å and three ...
Stefan Holler   +2 more
doaj   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

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