A comprehensive assessment of four whole blood stabilizers for flow-cytometric analysis of leukocyte populations [PDF]
Though cryopreservation of cell fractions is widely used in flow cytometry studies, whole blood cryopreservation is more challenging due to the presence of erythrocytes and effects of fixatives commonly used for preservation.
Cabrera, Luz E. +9 more
core +2 more sources
The effect of low doses of glyphosate on reactive oxygen species production by human granulocytes [PDF]
Glyphosate is the base of numerous herbicides used widely all over the world. Strong hepato- and nephrotoxicity of high doses of this reagent was reported in laboratory animal studies.
Jacek Sikora +2 more
doaj +2 more sources
Production of viable and functional neutrophils in granulocyte concentrates with the Reveos automated system. [PDF]
Abstract Background and Objectives Granulocyte transfusions may benefit patients with neutropaenia and life‐threatening infections unresponsive to antimicrobial therapies. Current aphaeresis‐based granulocyte concentrate (GC) production requires donor stimulation and hydroxyethyl starch (HES), which raises safety and supply concerns.
Fonseca S +4 more
europepmc +2 more sources
Determining the role of basophil activation testing in reported type 1 allergy to beta-lactam antibiotics. [PDF]
Background: Allergy to beta-lactam antibiotics (BLA), especially to penicillin, is the most commonly reported drug allergy by patients. Alternative antibiotics can yield negative consequences, such as extended hospitalization days due to less efficacy ...
Reitmajer M +7 more
europepmc +3 more sources
Anaphylaxis to a blood feeding leech. [PDF]
Pediatric Allergy and Immunology, Volume 36, Issue 3, March 2025.
Li CH +12 more
europepmc +2 more sources
Theranostic Toolbox for Neutrophil Functionalization. [PDF]
Here, neutrophil‐specific fluorine nanoparticles additionally equipped with either activating or inhibiting peptides for a background‐free 19F MRI‐based nanotheranostic approach are engineered. It is demonstrated that this approach is suitable to visualize and concomitantly direct neutrophil functionality depending on the specific requirements to ...
Bouvain P +11 more
europepmc +2 more sources
Activin A impairs ActRIIA+ neutrophil recruitment into infected skin of mice
Summary: Activin A levels are elevated during multiple severe infections and associated with an increased risk of death. However, the role of activin A in bacterial infection is still unclear. Here, we found that activin A levels were increased during S.
Yan Qi +8 more
doaj +1 more source
Background: Migration, production of reactive oxygen species (ROS), release of myeloperoxidase (MPO), and NETosis are functional immunological reactions of elementary importance for polymorphonuclear neutrophils (PMN).
Richard F. Kraus +2 more
doaj +1 more source
Neutrophils Require Activation to Express Functional Cell-Surface Complement Receptor Immunoglobulin
The phagocytosis-promoting complement receptor, Complement Receptor Immunoglobulin (CRIg), is exclusively expressed on macrophages. It has been demonstrated that expression in macrophages could be modulated by inflammatory mediators, including cytokines.
Annabelle G. Small +19 more
doaj +1 more source
Acute cigarette smoke-induced eQTL affects formyl peptide receptor expression and lung function [PDF]
Background and objective Cigarette smoking is one of the most prevalent causes of preventable deaths worldwide, leading to chronic diseases, including chronic obstructive pulmonary disease (COPD).
Berg, Marijn +7 more
core +1 more source

