Results 41 to 50 of about 1,607 (109)
Allergy, Volume 80, Issue 8, Page 2097-2112, August 2025.ABSTRACT The basophil activation test (BAT) is gaining increasing relevance as an ex vivo functional assay in allergy to evaluate IgE‐mediated hypersensitivity reactions to food allergens, venoms, and drugs and to monitor tolerance induction. Establishing universal standard operating protocols has been difficult, due to several challenges including ...
Mariona Pascal +18 more
wiley +1 more source
Non-canonical Roles of tRNAs and tRNA Mimics in Bacterial Cell Biology [PDF]
, 2016 Transfer RNAs (tRNAs) are the macromolecules that transfer activated amino acids from aminoacyl‐tRNA synthetases to the ribosome, where they are used for the mRNA guided synthesis of proteins.
Elgamal, Sara +3 more
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Identifying Aberrant Metabolism And Underlying Biology In Colorectal Cancer Tumors Between Early- And Later-Onset Samples [PDF]
, 2023 Early-onset colorectal cancer (EO-CRC) occurring in individuals under age 50 is rapidly increasing globally. In comparison, later-onset colorectal cancer (LO-CRC) incidence has decreased or remained stable over recent years. Despite these increases in EO-
Janak, Allison Paige
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Advanced Healthcare Materials, Volume 14, Issue 10, April 15, 2025.The challenges of studying inflammatory bowel disease (IBD), highlighting limitations of traditional 2D cell cultures and animal models are discussed here. It introduces human intestine organ‐on‐chip (OoC) models as a promising alternative, capable of more accurately mimicking the intestinal microenvironment.
Tim Kaden +5 more
wiley +1 more source
Potential therapies for acute‐on‐chronic liver failure
Liver International, Volume 45, Issue 3, March 2025.Abstract Acute‐on‐chronic liver failure (ACLF) is a syndrome that develops in approximately 30% of patients hospitalised with cirrhosis and is characterised by an acute decompensation of liver function associated with extra‐hepatic organ failures and a high short‐term mortality.
Maura A. Morrison +4 more
wiley +1 more source
Effects of Exercise Training on Neutrophil Proliferation and Function In Cancer Patients [PDF]
, 2021 Cancer and its treatments, namely chemotherapy and radiation, lead to negative physiological consequences. Neutrophils are the most abundant leukocytes in circulation with several studies pointing to the impact of cancer and its treatments lowering the ...
Ward, Nicholas
core +4 more sources
Neutrophil-derived microvesicle induced dysfunction of brain microvascular endothelial cells in vitro [PDF]
, 2019 The blood-brain barrier (BBB), composed of brain microvascular endothelial cells (BMEC) that are tightly linked by tight junction (TJ) proteins, restricts the movement of molecules between the periphery and the central nervous system.
Anjana Ajikumar +8 more
core +1 more source
Mechanisms of immunity in acutely decompensated cirrhosis and acute‐on‐chronic liver failure
Liver International, Volume 45, Issue 3, March 2025.Abstract The identification of systemic inflammation (SI) as a central player in the orchestration of acute‐on‐chronic liver failure (ACLF) has opened new avenues for the understanding of the pathophysiological mechanisms underlying this disease condition.
Cornelius Engelmann +2 more
wiley +1 more source
Advanced Science, Volume 12, Issue 6, February 10, 2025.Utilizing TetherChip technology, the authors revealed that primary and differentiated neutrophils produce tubulin‐based microtentacles. These microtentacles facilitated homotypic clustering, reattachment, and heterotypic clustering, which are inhibited with the tubulin depolymerizer, Vinorelbine.
Julia A. Ju +10 more
wiley +1 more source
The role of tRNA in development [PDF]
, 1972 Experiments that suggest a developmental regulatory role for tRNA in translation (such cytokinins in tRNA, suppressor mutations, tRNA methyases, excessive number of isoaccepting species, and others) are briefly presented. Reports that link changes in the
Dure, Leon S. III, Merrick, William C.
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