Results 61 to 70 of about 46,339 (291)

Trametinib in Adults with Neurofibromatosis Type 1‐Related Symptomatic Plexiform Neurofibromas

Annals of Neurology, EarlyView.
Objective Mitogen‐activated protein kinase kinase inhibitors have shown promising results in treatment of plexiform neurofibromas in neurofibromatosis type 1 patients, but data in adults are limited. The aim of this phase 2 study was to investigate the efficacy and safety of trametinib in adults with neurofibromatosis type 1.
D. Christine Noordhoek, David F. Hanff, Pim J. French, Sarah A. van Dijk, Erik A.C. Wiemer, Olivier C. Manintveld, Martin J. van den Bent, Walter Taal   +7 more
wiley   +1 more source

The change in NT-pro-BNP and post-PTMC echocardiography parameters in patients with mitral stenosis. A pilot study

Romanian Journal of Internal Medicine, 2017
Background. The change in the level of NT-pro-BNP (N-terminal-pro-Brain Natriuretic Peptide) is now considered as a reflection of the hemodynamic alterations and its circulatory reductions reported early after successful PTMC (percutaneous transvenous ...
Safi Morteza, Bayat Fariba, Ahmadi Zahra, Shekarchizadeh Masood, Khaheshi Isa, Naderian Mohammadreza   +5 more
doaj   +1 more source

Impact of DPP-4 inhibitors on plasma levels of BNP and NT-pro-BNP in type 2 diabetes mellitus

Diabetology & Metabolic Syndrome, 2022
Background Dipeptidyl peptidase-4 inhibitors (DPP-4i) decrease glucose levels by regulating incretin peptides in type 2 diabetes mellitus (T2DM). This study aimed to determine the modulatory effect of DPP-4i on brain natriuretic peptide (BNP) and N ...
Liying Mu, Zhuo Wang, Jinmei Ren, Xiaowei Xiong, Zening Jin, Xin Liu   +5 more
doaj   +1 more source

The interpretation of brain natriuretic peptide in critical care patients; will it ever be useful? [PDF]

, 2010
The measurement of B-type natriuretic peptide (BNP) is recommended for the diagnosis of decompensated heart failure, the prognosis of chronic heart failure is worse if BNP is increased and studies suggest that BNP is useful to guide therapy.
Dixon, J, Philips, B
core   +2 more sources

Case‐Based Immunology: B Cells and Systemic Sclerosis Interstitial Lung Disease

Arthritis &Rheumatology, EarlyView.
Interstitial lung disease (ILD) is an important complication of systemic sclerosis (SSc), with high mortality and morbidity. Recent clinical studies in SSc‐ILD have led to US Food and Drug Administration–approved therapies in SSc‐ILD. Importantly, evidence from these studies has been extrapolated to guide management of ILDs of other systemic autoimmune
Nina Goldman, Voon Ong, Christopher P. Denton   +2 more
wiley   +1 more source

Association of genetic polymorphisms of brain natriuretic peptide with cardiovascular diseases

Российский кардиологический журнал
Currently, natriuretic peptides (including brain natriuretic peptide (BNP)) are widely used in clinical practice as biomarkers for various cardiovascular diseases.
A. Ya. Panarina, G. I. Lifshits
doaj   +1 more source

Biomarkers and low risk in heart failure. Data from COACH and TRIUMPH [PDF]

, 2015
Aim Traditionally, risk stratification in heart failure (HF) emphasizes assessment of high risk. We aimed to determine if biomarkers could identify patients with HF at low risk for death or HF rehospitalization.
Anand, Behnes, Boer, Boer, Boer, Boer, Chen, Cheng, Christenson, De Boer, DeLong, Edelmann, Fonarow, Fonarow, Gheorghiade, Grafft, Jaarsma, Jaarsma, Jencks, Kimmenade, Levy, Lok, Maisel, Marti, Masson, Meijers, Meijers, Motiwala, O'Brien, O'Connor, Ouwerkerk, Peacock, Pencina, Phillips, Postmus, Rahimi, Ruifrok, Salah, Setoguchi, Sharma, Stewart, Troughton, Vazquez, Velde, Veldhuisen, Yancy, Yu   +46 more
core   +1 more source

Long‐Term Outcomes of Reduced Intensity Conditioning Hematopoietic Stem Cell Transplantation for Systemic Sclerosis Patients with Impaired Cardiac Function

Arthritis &Rheumatology, Accepted Article.
Objective High intensity conditioning autologous hematopoietic stem cell transplantation (AHSCT) is standard of care for patients with advanced SSc. The role of reduced intensity conditioning (RIC) prior to AHSCT in this population remains unclear. We conducted this study to determine the long‐term outcomes of RIC AHSCT in SSc patients with cardiac ...
Yonatan Lean, Carrie Richardson, Anthony Esposito, Katy Bedjeti, George E. Georges   +4 more
wiley   +1 more source

Clinical significance of brain natriuretic peptide and N-terminal pro-brain natriuretic peptide monitoring in type 2 diabetes mellitus

Сахарный диабет
Brain natriuretic peptide (BNP) and N-terminal pro-brain natriuretic peptide (NT-proBNP) are polypeptide hormones released by cardiomyocytes in response to cardiac volume or pressure overload.
I. A. Bondar, A. A. Demin, D. V. Grazhdankina, I. P. Krasnopevtseva   +3 more
doaj   +1 more source

NT-proBNP: A Biochemical Marker of Maternal Complications in Pre-eclampsia [PDF]

Journal of Clinical and Diagnostic Research, 2017
Introduction: Elevated serum levels of NT-proBNP (N terminal pro-Brain Natriuretic Peptide) are associated with Pre-Eclampsia (PE) and its complications.
Supriya Kumari, Mamta Gupta, Harsh Vardhan, Vandana Saini, SK Gupta   +4 more
doaj   +1 more source