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Interaction of N1-unsubstituted and N1-benzenesulfonyltryptamines at h5-HT6 receptors
Bioorganic & Medicinal Chemistry Letters, 2006Despite possessing a common tryptaminergic scaffold, examination of 28 (i.e., 14 pairs of) compounds suggests that N1-unsubstituted and N1-benzenesulfonyltryptamines likely bind at h5-HT6 receptors in a dissimilar manner (r2=0.201). Additionally, an examination of two rotationally constrained N1-benzenesulfonyltryptamine analogs indicates that a non ...
Renata, Kolanos +3 more
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Synthesis of N1,N1,N3,N3-tetrasubstituted diethylenetriamines
Russian Chemical Bulletin, 2018Preparative procedures for the synthesis of N1,N1,N3,N3-tetrasubstituted diethylenetriamines via aminoalkylation of N,N-disubstituted ethylenediamines with N,N-disubstituted 2-chloroethylamines were developed. Aminoalkylation of N,N-dimethylethylenediamine under heating gave simultaneously secondary N1,N1,N3,N3-tetrasubstituted diethylenetriamines and ...
D. Q. Hoang +4 more
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Structure of N1,N1-(3-oxapentamethylene)-N2-phenylacetamidine
Acta Crystallographica Section C Crystal Structure Communications, 1990C 12 H 16 N 2 O cristallise dans Pbca avec a=9,970, b=33,715, c=6,687 A, Z=8; affinement jusqu'a R=0,043. La molecule a une configuration trans. Le groupe amidine n'est pas plan, l'atome N 1 etant entoure d'une pyramide. Le cycle morpholine adopte une conformation chaise. Les liaisons C−N 1 et C=N 2 sont differentes (1,371 et 1,283 A respectivement),
E. Ciszak +2 more
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